Yara Sarkis, MD Profile picture
Aug 22, 2022 6 tweets 19 min read Read on X
@MondayNightIBD 1/ Hello and Welcome to today's #MondayNightIBD #Back2Basics!

Classifications are💎in IBD‼️Why⁉️:
🔹Clear assessment of disease location/extent/behavior
🔹Objective measure of flare severity
🔹Objective measure of endoscopic activity
➡️Determine treatment and prognosis‼️ Image
@MondayNightIBD @MN_GIMD @JosephHabibi_MD @DCharabaty @RomyChamoun @AllonKahn @drsusankais 2/ Classifications in CD:
1⃣Montreal Classification🟰Clinical Classification:
🔹A=Age at dx, L=Location in GI tract, B=Behavior (cf. Slide)
⚠️Behavior pearls:
🔻B1 can progress into B2 or B3
🔻Pts can present with B2 or B3 or both
🔻Perianal disease possible with any B phenotype Image
@MondayNightIBD @MN_GIMD @JosephHabibi_MD @DCharabaty @RomyChamoun @AllonKahn @drsusankais @AdvaniRashmiMD @DVinsard @SanjeevaniTomar @BassiMehak @GroverDheera 3/ Crohn's disease activity index (CDAI) 🟰 Clinical score
🔹Assess disease activity
🔹Quantify symptoms
🔹8 variables
🔹Index score
🔻<150: Remission
🔻221-450: Mod to Severe Image
@MondayNightIBD @MN_GIMD @JosephHabibi_MD @DCharabaty @RomyChamoun @AllonKahn @drsusankais @AdvaniRashmiMD @DVinsard @SanjeevaniTomar @BassiMehak @GroverDheera @dunleavy_katie @LindaNguyenMD @LinChangMD @JPAchkarMD @SultanMahmoodMD 4/ Simplified Endoscopic Activity Score for Crohn’s Disease (SES-CD):
🔹Most commonly used endoscopic scoring system for CD
🔹Proposed in 2004
🔹Replaced CDEIS‼️
🔹Correlation with CDAI, and non-invasive markers of disease such as calprotectin➡️👁️ @ReenaKhanna159's Review Image
@MondayNightIBD @MN_GIMD @JosephHabibi_MD @DCharabaty @RomyChamoun @AllonKahn @drsusankais @AdvaniRashmiMD @DVinsard @SanjeevaniTomar @BassiMehak @GroverDheera @dunleavy_katie @LindaNguyenMD @LinChangMD @JPAchkarMD @SultanMahmoodMD @ReenaKhanna159 @rajVuppaLanchi @BilalMohammadMD 5/ SES-CD:
🔹Quantify common endoscopic findings in different parts of the bowel:
🔻Size of ulcers
🔻Extent of ulcerated surface
🔻Extent of affected surface
🔻Presence of strictures

✅Values are calculated for each segment and totaled at end. Higher score🟰worse Image
@MondayNightIBD @MN_GIMD @JosephHabibi_MD @DCharabaty @RomyChamoun @AllonKahn @drsusankais @AdvaniRashmiMD @DVinsard @SanjeevaniTomar @BassiMehak @GroverDheera @dunleavy_katie @LindaNguyenMD @LinChangMD @JPAchkarMD @SultanMahmoodMD @ReenaKhanna159 @rajVuppaLanchi @BilalMohammadMD @HaniShamseddeen @MvenuGI @gastrodocmattar 6/ Rutgeerts Score 🟰 Post-op ileal CD endoscopic score:
🔹Assess post-op recurrence in ileum
🔮Predict disease progression & need for another✂️
🔹Rutgeerts i2 or higher -> Start or modify current Rx to prevent dis. progression & need for another Surgery✂️in the future Image

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Yara Sarkis, MD

Yara Sarkis, MD Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @yaransarkis

Apr 17, 2023
@MondayNightIBD 1/Differential of Non-infectious Non -IBD colitis:
🔆 Drug-induced
🔆 Common Variable Immunodeficiency
🔆 Behcet disease
🔆 Segmental Colitis Associated w/ Diverticulosis
🔆 Ischemic Colitis
🔆 Radiation Colitis
🔆 Malignancy

🤔Can you think of other dx?
#MondayNightIBD
@MondayNightIBD 2/Immune Checkpoint Inhibitor Enterocolitis
📌ICI = monoclonal antibodies that reactivate immune response to tumor cells
📌Activation of T‐cells can cross‐react with host antigens
📌Enterocolitis ⬆️anti‐CTLA‐4 > anti‐PD‐1/PD‐L1 agents
📌Diarrhea
⬆️risk perforation if unrecognized Image
@MondayNightIBD @SanjeevaniTomar @halesj126 @JosephHabibi_MD @RomyChamoun @MarcelYibirin @ifrahfatima @GroverDheera @dunleavy_katie @drsophiadar @Spencerkelley7 3/ICI + Diarrhea:
📐R/o infection
🔦C-Scope: appearance of IBD; but mucosa can look normal -> always biopsy; consider EGD +Bx
🔬Path can have chronic IBD changes, crypt apoptosis
💊Depends on severity: budesonide -> IV steroids-> Biologic
#IBDAlgorithm👇
Image
Read 16 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us!

:(