Dr. Thierry Facon making a compelling argument for autologous stem cell transplant for newly diagnosed myeloma. @Myeloma_Society#IMS2022
For high risk myeloma, its important to consider early transplant in the frontline setting.
For standard risk myeloma, we continue to prefer early transplant but in certain circumstance can delay transplant until first relapse accommodating patients’ wishes & life circumstances
For patients achieving MRD negative with induction therapy alone, early and delayed transplant gives similar outcomes. Thus an MRD directed approach to timing of transplant may the way of the future. Agree with @mvmateos#IMS2022
To emphasize for transplant eligible patients the importance of transplant in myeloma is not in question. The current debate post IFM and DETERMINATION trials is only concerning its timing. #IMS2022
The audience @Myeloma_Society when polled overwhelmingly support the role of transplant in myeloma. Like 99 to 1! #IMS2022
The MIDAS trial in IFM (France) is randomizing MRD negative patients to transplant vs no transplant. @End_myeloma is also leading a similar trial.
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This is the kind of lawsuit that makes people lose even more faith in the Pharmaceutical industry.
We have a pandemic costing millions of lives. And this is what their concern is? nbcnews.com/health/health-…
When so many including me were thanking Moderna, Pfizer, Astra Zeneca for rapidly producing vaccines, we were also defending you from those who alleged you were solely doing this for profit.
I cannot defend you any more.
I was disappointed and upset that companies were not transferring technology and resources to make vaccines available for poor countries.
I am even more upset now. It clearly looks like the profit you made in your mind was not adequate enough. Seriously?
Although we have multiple options to treat myeloma, the number of highly effective drug classes are few and just not enough.
We continue to have an unmet need for relapsed myeloma. We continue to need accelerated approval by the FDA. @Rfonsi1@NorthTxMSG#IMS2022#IMS2022VR 1/
We also need accelerated approval of multiple drugs of the same class because patients tolerate one better than the other, and sometimes one works better than the other. It is also important to have competition to foster more innovation and to have some effect on price.
2/
The fact we have made so much progress in myeloma does not mean we don’t need more drugs.
Myeloma remains a serious malignancy and we continue to have unmet needs. So I will continue to advocate for rapid approval of new drugs.
3/
COVID vaccines were developed in record time against the origins wild strain 2 years ago. The virus has since mutated multiple times. We need the modified boosters to protect lives.