Dr. Thierry Facon making a compelling argument for autologous stem cell transplant for newly diagnosed myeloma. @Myeloma_Society #IMS2022
For high risk myeloma, its important to consider early transplant in the frontline setting.

For standard risk myeloma, we continue to prefer early transplant but in certain circumstance can delay transplant until first relapse accommodating patients’ wishes & life circumstances
For patients achieving MRD negative with induction therapy alone, early and delayed transplant gives similar outcomes. Thus an MRD directed approach to timing of transplant may the way of the future. Agree with @mvmateos #IMS2022
To emphasize for transplant eligible patients the importance of transplant in myeloma is not in question. The current debate post IFM and DETERMINATION trials is only concerning its timing. #IMS2022
The audience @Myeloma_Society when polled overwhelmingly support the role of transplant in myeloma. Like 99 to 1!
#IMS2022
The MIDAS trial in IFM (France) is randomizing MRD negative patients to transplant vs no transplant. @End_myeloma is also leading a similar trial.

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More from @VincentRK

Aug 26
This is the kind of lawsuit that makes people lose even more faith in the Pharmaceutical industry.

We have a pandemic costing millions of lives. And this is what their concern is? nbcnews.com/health/health-…
When so many including me were thanking Moderna, Pfizer, Astra Zeneca for rapidly producing vaccines, we were also defending you from those who alleged you were solely doing this for profit.

I cannot defend you any more.
I was disappointed and upset that companies were not transferring technology and resources to make vaccines available for poor countries.

I am even more upset now. It clearly looks like the profit you made in your mind was not adequate enough. Seriously?
Read 4 tweets
Aug 24
Although we have multiple options to treat myeloma, the number of highly effective drug classes are few and just not enough.

We continue to have an unmet need for relapsed myeloma. We continue to need accelerated approval by the FDA. @Rfonsi1 @NorthTxMSG #IMS2022 #IMS2022VR
1/ Image
We also need accelerated approval of multiple drugs of the same class because patients tolerate one better than the other, and sometimes one works better than the other. It is also important to have competition to foster more innovation and to have some effect on price.

2/
The fact we have made so much progress in myeloma does not mean we don’t need more drugs.

Myeloma remains a serious malignancy and we continue to have unmet needs. So I will continue to advocate for rapid approval of new drugs.
3/
Read 10 tweets
Aug 24
I will get the updated COVID vaccine boosters as soon as they are available. nbcnews.com/news/amp/rcna4…
COVID vaccines have saved countless lives. I’m glad to see vaccines modified to target new variants. ourworldindata.org/covid-deaths-b…
COVID vaccines were developed in record time against the origins wild strain 2 years ago. The virus has since mutated multiple times. We need the modified boosters to protect lives.
Read 4 tweets
Aug 23
US life expectancy fell in ALL 50 states in 2020. By almost 2 years. That’s unprecedented.

Main reason: COVID
axios.com/2022/08/23/us-…
The US already does quite poorly in life expectancy compared to other developed countries.

We need to focus on health. Public health. Access. Affordability.
Just having the fanciest hospitals and the fanciest new meds is not enough.

There is no fancy medicine that can improve disparities in health care access, affordability, education, income, socioeconomic status.
Read 5 tweets
Aug 22
Same drug, different price.

No it’s not a scam! It’s reality. Read on.
1/
Anytime you hear 98% discount, no one will blame you for thinking it’s a scam.

But this is not a scam. It’s reality. Same drug: in this example it’s one of the most important cancer drugs of all time.

$10,000 or $100. Take your pick. @GoodRx
2/
Or you can get it for $39 @costplusdrugs @mcuban @alexosh

Yes! It’s true!
3/
Read 10 tweets
Aug 19
How would you feel if you went to buy gas and it costs you $12 a gallon because you were poor?

Well. It’s happening in healthcare. Read on.
1/
2 patients walk into a US pharmacy to buy the exact same medication.

The medicine has a different price for each person!
2/
Cost of same medicine could be:

$100 for the insured split between patient and insurance company

$300 for the uninsured: out of pocket.

Poor/immigrant/visitor without insurance?
The drug cost is 3 times higher. If you are lucky.

It could be 10 times higher too!
3/
Read 9 tweets

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