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Dr Satoshi Akima FRACP 『秋間聰』 Profile picture
@ToshiAkima
Aug 31, 2022 • 3 tweets • 2 min read • Read on X
1. There is only one reason to reduce the isolation period to 5 days. And that is because you want to kill more people, while accelerating spread in the workplace, thus exacerbating worker absenteeism to undermine the economy
2. This self-destructive economic plan based on culling social ballast to set free the economy is #NegativePopulationEconomics unleashed by the architects of annihilation and represents Social Darwinism at its worst
3. Those who have rekindled a neoclassical variant of #NegativePopulationEconomics may not recognise themselves characterised as such, but that is what their macroeconomic principles are tantamount to.

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More from @ToshiAkima

Dr Satoshi Akima FRACP 『秋間聰』 Profile picture
Oct 19
I was always suspicious of the thousands of freshly minted clichéd Canadian trucker convoy and MAGA accounts pushing anti-vaxx propaganda. You'd block a thousand only to have a thousand more appear. They'd all repeat the same set of messages over and over.
We clinicians are naive. All we could do in reply to the misinformation campaign was quote some RCT as though it were a scientific debate, when really it was an act of war. Yes, a proxy war waged by atypical means, but a war nonetheless.
As they got the UK to shoot itself in the foot with Brexit, the troll farms politicised the bipartisan issue of vaccination. The result was a civil war waged with biological agents, causing an enormous mortality disparity between left and right.
Read 6 tweets
Dr Satoshi Akima FRACP 『秋間聰』 Profile picture
Aug 29
The paper is now out in @Nature after I tweeted on this oral presentation @ISTH 2023 by @AkassoglouLab. Fibrin/fibrinogen may be a therapeutic target in СОVΙD neuropathology. Link in next tweet.
“...results reveal a role for fibrinogen as a SARS-CoV-2 spike-binding protein accelerating the formation of abnormal clots with increased inflammatory activity”…“fibrin-targeting immunotherapy suppresses SARS-CoV-2 pathogenesis”.

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From an #immunothrombosis perspective, this paper now shows fibrinogen to be a far more critical player in this field than previously thought. We used to focus more on contact, TF, and thrombin but now must look further downstream in the fibrinogenesis/fibrinolysis pathways too.
Read 7 tweets
Dr Satoshi Akima FRACP 『秋間聰』 Profile picture
Aug 8
It's not so bad a comparison if you accept that to get a similar “depletion of the susceptibles” by a Darwinian evolutionary mechanism, you'd have to deplete 2-400M vulnerable pheno-/genotypes from the pool.
It's always assumed that “evolve to become milder” means that the virus evolves, when it is just as likely that humans are “evolving” via a survival mechanism involving “depletion of the susceptibles”, leaving only those less prone to a lethal outcome. This, too, is evolution.
GBD types would likely argue that intervention to halt the depletion of the susceptibles is a perversion of the natural selection process and a crime. By opposing it, we are simply prolonging the pandemic.
Read 11 tweets
Dr Satoshi Akima FRACP 『秋間聰』 Profile picture
Aug 5
And this week's Grand Rounds “just a cold” is another young patient with enterovirus-induced fulminant myocarditis needing intubation, ECMO, and an Impella LVAD. I've never seen so many severe post-infectious complications presented in my life.
Last week's Grand Round? Another “just a cold” with Mycoplasma in a paediatric patient who developed encephalopathy, needing IV pulse methylprednisolone and IVIg. It's like every week we see a new case of previously rare infectious complications in young patients.
Another Grand Rounds case. A pregnant woman with severe cardiomyopathy caused by a combined adenovirus and enterovirus infections. Required ECMO.
Read 4 tweets
Dr Satoshi Akima FRACP 『秋間聰』 Profile picture
Aug 3
Subjecting trial subjects to wearing surgical mаsks against an airborne virus is like running a bike helmet RCT with subjects in Tupperware helmets that weren't designed for that purpose. “But we don't know it doesn't work until we run an RCT” isn't good enough.
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“But there was a 30% reduction in head injuries in the Tupperware group vs. placebo.” Not good enough! In a high-risk scenario for major head injury, a Tupperware helmet won't do. The magnitude of risk test subjects were exposed to needs investigation and quantification. Image
Non-pharmaceutical physical protective devices are subject to engineering standards of proof of efficacy. In the case of helmets, that means crash testing in a lab to see how they fare in high-risk situations that live subjects can't be exposed to. helmet.beam.vt.edu/lab.html
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Read 7 tweets
Dr Satoshi Akima FRACP 『秋間聰』 Profile picture
Jul 31
A reminder that there was once a titanic struggle between contagionists vs miasmatists over the mechanism of transmission of cholera before the need to cleanse the water of waterborne pathogens was accepted. We are going through a similar struggle today, fighting for clean air. abc.net.au/news/2024-07-3…
If you want to read about how divisive the debates between the contagionists and miasmatists was, you should read “Death in Hamburg” by @RichardEvans36. They didn't need Twitter back then to be almost reduced to pistols at dawn.
Quoted in the article by @Hayley_Gleeson is our latter-day Professor Pettenkofer from Down Under: “I want to believe…”
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Read 4 tweets

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