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Tyler Black, MD

@tylerblack32

Aug 30

https://twitter.com/ABDanielleSmith/status/1564710112547471360

Politicians using misinformation/disinformation for political gain on full display here.

COVID was a once-in-a-century pandemic and anyone claiming that shutting schools down harmed kids' mental health is not telling the story of what the evidence actually says (and doesn't say)

https://twitter.com/ABDanielleSmith/status/1564710112547471360

1) most studies do not separate the effect of the pandemic from the effect of shut downs

2) we have quite contradictory evidence on the effect on children's mental health from the pandemic as a whole, which takes quite a long time to sort out, but there is no overwhelming signal

3) some of the best research we have (longitudinal cohort studies, which are superior to cross sectional survey) shows that generally, mental health outcome effect sizes are robust, and some surprising improvements, and some pockets of deterioration

Read 15 tweets

Tyler Black, MD

@tylerblack32

Aug 23

@JusDayDa

DATA PRESENTATION

Basic data reporting principles include a comment on variation. Thanks to @JusDayDa for sending this to me. Arizona's Child Fatality Review program has excellent numbers but I cringe at the impact this would have on policymakers without understanding the data.

Here is the fluctuation in "percent form"

Male Female Year
+03% -45% 2012
-36% +9% 2013
+74% +12% 2014
+21% +29% 2015
-26% ------ 2016
+51% -08% 2017
+35% ------ 2018
-58% +30% 2019
+60% + 21% 2020

As you can see, 2020 wasn't a strange year.

The more pressing concern, obviously, is the general trend.

for boys (r-squared = 0.22, an extra 0.4/100k/year)
for girls (r-squared = 0.35, an extra 0.2/100k/year)

Read 5 tweets

Tyler Black, MD

@tylerblack32

Aug 21

The pharmacology of the brain (psychopharmacology) is complex & a rigorous, additive science.

Cue the anti-psychiatrists: "serotonin depression model debunked, claims that meds change brain chemistry is FRAUD!"

But, think about this for a moment. It's patently absurd.

/1

First, we know that SSRIs were specifically designed to alter serotonin (5HT) reuptake. There *was* an idea of "too little serotonin" but it was one of many 5HT theories, & when the medications were developed, they *worked*.

SSRIs work, and the science is clear on this.

/2

Even though SSRIs work, the psychopharmacology of depression treatments fell far away from the "5HT deficiency hypothesis", and scientists across the globe have been investigation the mechanisms of 5HT drugs and their role in treatment of depression.

/3

Read 14 tweets

Tyler Black, MD

@tylerblack32

Aug 12

@CDC

The @CDC's new guidance is like "people are going to smoke anyway, so we don't recommend that they don't smoke."

If the politics push against evidenced public health, the public health position should push against the politics! Not "oh the politics are bad here go ahead."

This capitulation to what "the public is accepting" is a failure of the basic duties of health care practitioners: to give people the best information in decisions regarding their health.

The CDC is going against *its own evidence* in its recommendations.

CDC's evidence is clear that:
1) masks work
2) mitigations work
3) vaccination is crucial
4) ventilation matters
5) even with a history of infection, vaccination prevents worse outcomes

Read 5 tweets

Tyler Black, MD

@tylerblack32

Aug 11

#astrophotography

5,000 light years away from us, in the constellation Cygnus, exists the "Crescent Nebula" (I call it the "Brain Nebula"). There is an "shock wave" of blue moving outward and a shockwave moving inward at about 2,000 km/sec.

/1

Pulling back we can see tremendous nebulosity of the Sadr region.

The central star of the Crescent Nebula will eventually explode in a supernova explosion.

/2

Zoomed out even further (as part of my 4 panel mosaic) we can see the bright star Sadr.

/3

Read 6 tweets

Tyler Black, MD

@tylerblack32

Aug 4

@CDCgov

🚨POST-COVID & Kids🚨

New @CDCgov report showing quite clearly that children are at significantly more risk for life-threatening diagnoses after COVID infection. Very convincing evidence that prevention of COVID-19 in children is very important to reduce childhood mortality.

/1

In every age demographic, life threatening and severe disorders are more significant after COVID infection. We also see a drop in muscle/neurological/psychiatric disorders post-COVID in kids. I have some hypotheses on that.

/2

This is true of symptoms (not diagnoses) as well, though less dramatically so.

/3

Read 7 tweets

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