Thread by @Joni_Coleman

After a brief break for questions, round 2 #wcpg2022

@immaqua describes OCD progress. GWAS ongoing (numerous hits - see symposium on Saturday) and shared with cross disorder efforts. Symptoms analyses yielding publications. Next freeze - diversity and addressing heterogeneity #WCPG2022

Tourettes syndrome WG: new GWAS freeze with GWS hits and replications. Numerous secondary analysis papers from trainees. CNV efforts as well. Oral session on Saturday. Future collaborations across imaging and functional analysis #WCPG2022

Outreach - PGC website updated pgc.unc.edu. Continuing working group takeovers of @PGCgenetics and promotion of lived experience commentary on psychiatric genetics. Expanding outreach to increase diversity and promote jobs and studies #WCPG2022 #livedexperiences

Pedigree sequencing. Deeply analysed 31 pedigrees. Want to boost diversity of disorder focussed as well as ancestries. Identified deleterious variants. Developed and published new methods. Work ongoing - need to understand more of role of noncoding variants #wcpg2022

@cnievergelt presents for PTSD - recent quantitative GWAS and CNV publications. Over 20 papers from subgroups. Expanding case control GWAS using electronic health records, including transancestry work. Contributing to cross disorder. Methods development cross ancestry #WCPG2022

@drjameswalters for SCZ: PGC3 published this year alongside SCHEMA paper, with convergent results. Early release of sumstats has led to lots of secondary analyses. Following up biological findings esp neuronal enrichment. Working to increase diversity #WCPG2022

Substance use - examining common genetic factors across substance use phenotypes. New variant discovery for individual substance use. Large GWASs in progress - reach out to collaborate! Interested in substance use in international context #wcpg2022

Suicide - fast growing new WG. Numerous GWAS of suicide attempt in EUR and across ancestries. Estimate heritability, find GWS associations. Consistent architecture across civilian and military cohorts. Not just MDD. Expanding rapidly and globally - connect to contribute #WCPG2022

Cross disorder from @jorsmo - many efforts across different methods through pooling disorders showing and dissecting overlap - see symposium on Saturday. Now 5 latent factors for psych disorders. #wcpg2022

@PGCgenetics always looking for new data and new collaborators - get in touch at pgc.unc.edu if you want to get involved! #wcpg2022