Watching a certain #ANDREWTATE on @patrickbetdavid's podcast. (Holy shitballs, 4 hours and 52 minutes.) This guy is really quite something
@patrickbetdavid Now that's a line. “The morgue, and the prison: both of them are full of egos.” (#AndrewTate, 3:00:27, @patrickbetdavid)
@patrickbetdavid Now he (#AndrewTate) is quoting his father's old tweets. (@tateterrific, dormant for years; father passed in 2015 is I think what I heard him say earlier)
@patrickbetdavid @tateterrific No idea if PBD would confirm or deny, but after Tate's riff on fathers, legacies, keeping his father alive etc, that PBD's eyes are wetter than usual. No visible tears, but I'm convinced he got that "swelling" feeling, ie the euphoria of seeing/hearing something that hits just so
~Three second cut, 3:23:26 - :29. Tell me that isn't @patrickbetdavid doing that thing where you catch your own breath during an inhale

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More from @CTZN5

Apr 7, 2020
ZINC

THE CONFOUNDING VARIABLE IS ZINC

GOD FUCKING DAMMIT HOW IS THIS NOT PROMULGATED YET
here's the fucking deal

to replicate a study where HCQ showed high promise, make sure pts/subjects consume a diet high in zinc, or, like, supplement

to replicate a study where HCQ was nearly ineffective, make sure to do the opposite
layman tldr

—Zn cockblocks *COV2's replication game in the cytosol
—normally v little Zn there; most extracellular
—HCQ: "zinc ionophore" (pulls Zn into cell)

but:
Read 7 tweets
Dec 1, 2019
@johanatan Currently just balance that’s off, and saccade speed is slowed
Update: Only minor effects as noted. Considering upping by a third 10 mg y/n
(Note I would simply augment with alcohol like any plausibly sane attempted psychonaut but the beer was smuggled by my father to The Compound and there appears to be no other potable EtOH in the house)
Read 16 tweets
Apr 11, 2019
inb4 why is this even remotely on my radar lol. basic answer is HyunA is p much the only kpop'er i like. but that's not why this is interesting
so, PSY is of course irreverent as hell and got megahuge and so decided after like a decade to just become his own label

meanwhile unless you're as big as PSY labels in korea are craaazy oppressive

one example is all the idol groups are contractually obligated to "stay single"
Read 10 tweets
Jan 19, 2019
@AlexSchleber (The thing that is learned, is the helplessness. So, here's what's happening. Think evolutionary biology for a sec. I'm a mammalian brain:

"In attempt to favorably influence [xyz aspects of my environment], I have explored [N] permutations on [q,r,s,etc] behavioral patterns. ...
@AlexSchleber ... None of them worked, and I have been unable to observe a pattern to any of my permutation-explorations that appears to affect these aspects. Therefore, based on the sum output state of calculation [F], energy is better off lowered for conservation, or else directed elsewhere"
Read 17 tweets
Jan 19, 2019
idk if it's unpopular or just depression is poorly described?

There are, broadly, two major etiologies of depression. But however you end up at that neurochemical place, "learned helplessness" and the neuro ways that occurs are behind it either way
Like literally it's the same thing. Depression is just what we call Learned Helplessness at a level clinically diagnosable as either

- inappropriate for the circumstances, &/or
- (strictly) neurophysically appropriate, but deleterious to patient's ability to exit circumstances
I realize this is not widely understood, as modern medicine is a very mixed bag and psych in particular is pretty much a total shitshow (eg still in leeches for bloodletting territory)

but it would be nice if people and psychiatry could start to catch on to this simple framework
Read 11 tweets
Jan 6, 2019
any of you who've had me tell you "commercial melatonin supps are way overdosed", here's another reminder

you want like 0.5mg melatonin at most, 0.3 ideally; more will work no better but will desensitise your MT receptors
*also* holy retweets, don't panic. As far as receptors to throw out of cal, MTNR1x are def among the least troublesome and simplest to fix

i can name this tune in ... three more tweets
Receptor circuits are always in self-cal. Cal "cycle" periodicity can be as short as minutes on some to weeks on others. Some are little more than a single autoreceptor. Others? The size, extent, and sophistication of the feedback/control circuits are like nothing yet terrestrial
Read 9 tweets

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