ACIP slides: it is a BAD decision to add this to the SCHEDULE 👇

This vaccine has (a) no convincing evidence it helps the 86% of kids who already had covid & (b) no evidence it will help kids in 2027 against whatever new strain comes

CDC data shows parents don't want it🧵
93.1% of parents don't want to vaccinate their young kids

That is for good reason; there is no RCT data this vaccine lowers severe disease in this age group, and even the observational studies I am aware of (flawed) look at 5-11

No study pertains to kids where 86% had covid
CDC slides also full of errors and bad decisions

They are stacking 2 booster doses in adolescents-- this should raise concern of unnecessary myocarditis that might be averted with omission or spacing the last dose
They assert this as fact, but surely at some point the calculus tips

a 20 year old man who got 3 doses and just had OMICRON- benefits from a bivalent booster targetting an earlier strain?

No evidence supports this, and it is nonsensical

What about dose #20?
This slide does not account for changing facts on the ground. Omicron and prior immunity have drastically changed these numbers

PS these numbers we also wrong when they first put them forth, as we explained…
Denmark is limiting vaccination to kids and young people.

US CDC has lost perspective, they are out of touch with data, the American people, and common sense

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More from @VPrasadMDMPH

Oct 21
CDC wants it both ways
Obviously, having had and recovered from covid is protective against future bad Covid. They admit that here👇

At the same time, they want to say you have to keep getting boosted even if you have JUST HAD COVID

Stupid policies
Bc of incompetence
If having had COVID and recovered lowers the risk of future severe disease

MAYBE your recs should include this.
86% have had Covid and yet for vaccination they make no accomodation for it.

For their VE stat they say it would have been better if not for natural immunity

Their brain is broken
Read 4 tweets
Oct 19
CDC does not make vaccine requirements, but they clearly play a huge role. The more they endorse covid vax the more they pave the way. I owe my unnecessary booster mandate to them

You have to be incompetent to think a kid who had covid MUST get COVID vax. Just no good data
Other countries recognize this and don't push so hard.

It's not even the CDC making these decisions. It's a handful of people who were appointed by the White House because they liked their CNN spots.

Policy is not being set by competent people
Read 4 tweets
Oct 15
Over the last 10 years, I have published 17 articles on screening (~5% of @vkprasadlab's focus)

I am going to make them all available free in a thread
If you read them all, you may think differently/ more clearly about screening

#1 Most don't change OS…
#2 Powering cancer trials for all cause mortality is feasible, practical and tractable;

We ought to do it to truly learn if off-target harms offset disease specific gains.…
#3 Blood based screening for colon cancer: A disruptive innovation or just a disruption?…
Read 23 tweets
Oct 15
Our obsession with masking, an intervention w/ terrible evidence base, is crazy

Fauci was honest the 1st time on 60 mins; Pre-pandemic data was poor; it was not recommended 4 good reason

Yet With poor evidence, many pushed for them 🧵…
That would have been ok, had they also pushed for cluster RCTs, but they did not

This is b/c they are arrogant, and don't understand the need for randomization (smoking bad eg 👇)

That was the original sin b/c without data, it would become political
The most accurate history of the mask obsession is this essay

They call it a debacle for a reason

It was an evidence based fiasco…
Read 7 tweets
Oct 14
Another win for @nytimes covid coverage.

They managed to cover the study without mentioning that a 16% response rate to a survey is so abysmal that no medical journal would publish it under normal circumstances. It would wind up in the trash.

Next they will cover Twitter polls.

Aka. The best science has to offer!
Can you cover schools again?

Too many are open and kids are fine and recovering from learning loss. Maybe you can help us there like you did before.
Read 4 tweets
Oct 13
As a Dem, I think it is way more dangerous to selectively cry misinfo for our political opponents & demand unis punish

Here is e.g. of Ashish Jha amplifying a trash analysis that serves his unproven policy goal (no RCT). Yet no editorial in Science. 1/5…
It's no secret that Republicans are an endangered species in academic medicine and public health.

I am a Bernie Sanders supporter who wrote 2 books on strengthening the regulatory state (read them) but even I can see how this will be abused to make endangered, extinct.
There is a broader debate about how many shots are necessary for a 20 year old man. That is apolitical.

Selectively crying misinfo & demanding academic freedom be paved over is the road to hell

Someday we Dems may be in minority in University. sometimes Dems get things wrong
Read 16 tweets

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