Bactrim is fine for most beta-hemolytic strep, folks.

Many of us were taught this one incorrectly because thymidine content in agar unregulated until 2006 so looked resistant in old studies.

Appreciate @SDoernberg clearing this one up in 2nd myth busters talk.

#IDWeek2022 ImageImageImageImage
Nice aside - dosing matters.

Most people I'm consulted on who fail oral treatment for true cellulitis are underdosed.

#IDWeek2022 Image
Clinical data on PCN vs TMP/SMX and Clinda vs TMP/SMX.

#IDWeek2022 ImageImageImageImage
Considerations for making choice.

I'll typically choose beta lactam for nonpurulent cellulitis, but I'm perfectly fine using Bactrim monotherapy if I think might be mixed/MRSA concern or a reason not to use a beta lactam.

Don't use clinda.
Doxy not good 4 strep.

#IDWeek2022 Image

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More from @NateShivelyMD

Oct 22
What drives physicians refusing ASP recommendations?

We looked into it.

Just got done presenting our #IDWeek2022 oral abstract.
#IDTwitter

🧵

1/ Image
First, there are a bunch of ways to do TeleASP, but especially the more "intense" models have shown success and can be as good as on-site programs.

Our prior work: academic.oup.com/cid/article/71…

SCORE trial from @E_Stenehjem et al.: academic.oup.com/cid/article/67…

#IDWeek2022

2/ Image
What do we know already about what influences rec acceptance?

Summary of prior work, including great work from @BRxAD - surgeons tend to be less accepting, and recs that reduce antibiotic exposure refused more.

3/ Image
Read 16 tweets
Oct 22
Oral Therapy for Bacteremia and Endocarditis

@IDwithNWD giving talk for @BradSpellberg

"No, you're not in the wrong room, and @BradSpellberg did not get younger and more handsome."

#IDWeek2022
#IDTwitter Image
Historical lesson first.

Where did the myth that we need IV for IE come from?

Have to go back a ways.

#IDWeek2022 ImageImageImageImage
The dooming quote.

#IDWeek2022 Image
Read 12 tweets
Oct 21
What's better for reducing unnecessary treatment of asymptomatic bacteriuria? Diagnostic stewardship or antibiotic stewardship?

@ValerieVaughnMD presenting the @SHEA_Epi featured oral abstract.

#IDWeek2022 ImageImage
Pathway to overuse and opportunities to intervene.

#IDWeek2022 Image
Diagnostic stewardship metric was ASB (treated or not) / +UCx

#IDWeek2022 ImageImage
Read 8 tweets
Oct 21
Nice follow up talk from @ValerieVaughnMD - always great stuff from her.

#IDWeek2022 Image
Anyone ever seen a patient like this?

(For hospitalists like @ValerieVaughnMD and those of us that review patients with ASP, every day, multiple times per day)

#IDWeek2022 ImageImageImageImage
A note that what we call overdiagnosis for infections, others may call inappropriate diagnosis.

#IDWeek2022 Image
Read 8 tweets
Oct 21
I don't know anyone that is more excited about urine than @Sonali_Advani.

Some highlights from her great talk this morning ⬇️

#IDWeek2022
Lots of factors go into inappropriate culturing.

Physicians more driven by labs, nurses by appearance/smell.

Education can help.

#IDWeek2022
Tough group is the 3rd box.

Yep.

#IDWeek2022
Read 9 tweets

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