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Radical Centrist, wrathful tantric deity 🇺🇦 Profile picture
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Oct 22 • 5 tweets • 2 min read
SARS2 hypoimmunity from ‘letting it rip’ finally going (somewhat) mainstream:

washingtonpost.com/health/2022/10…
Been saying this for some time!

mobile.twitter.com/search?q=%40ra…
🚨 As I’ve been saying for YEARS now…the best available comparison for the public to understand the long-term effects of Covid is:

HIV.
cleveland.com/news/2022/10/i…
“Why compare anything?” you may say. Simple.

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More from @RadCentrism

Radical Centrist, wrathful tantric deity 🇺🇦 Profile picture
Oct 12
“These data challenge the idea of a protective contribution of pre-existing memory CD4+ T cells to SARS-CoV-2 immunity and even suggest a potential negative impact on the immune-response quality.”

cell.com/immunity/fullt…
“High-quality immune responses were in general connected to a low contribution of pre-existing memory…In contrast, pre-existing memory T cells seem to have low proliferative potential, leading to low-quality responses if not compensated, e.g., from the naive pool”
“We…analyzed whether pre-existing memory is an independent predictor of the T cell response quality.

“the Tmem frequency showed a strong negative correlation with the fold expansion of spike-specific T cells (Figure 3A ), which was confirmed for each individual age group”
Read 6 tweets
Radical Centrist, wrathful tantric deity 🇺🇦 Profile picture
Oct 10
A 🧵 on SARS2 “brain fog” mechanisms and pathologies.

Brain fog is no doubt a multi-mechanism phenomenon, so as info emerges I’ll update 🧵 with new findings/hypotheses.

I’ll start with my own thoughts, which are about lipids called 𝐜𝐞𝐫𝐚𝐦𝐢𝐝𝐞𝐬 (sciencedirect.com/topics/neurosc…).
SARS2 virus particles (virions) bind to our cells via the now-famous ACE2 receptor.

The primary reason that SARS2 is *so bad* is that ACE2 receptors are *expressed* in nearly all our tissues.

SARS2 therefore attacks—directly and indirectly—every organ in our bodies.
An interesting mechanism in the papers below is that SARS2 activates our “acid sphingomyelinase (ASM)-ceramide system,” causing our ACE2 receptors to CLUSTER. This clustering enhances viral entry.

Sadly it’s well documented that HIGHER ceramides correlate strongly with dementia.
Read 11 tweets
Radical Centrist, wrathful tantric deity 🇺🇦 Profile picture
Oct 10
“I believe with Schopenhauer that one of the strongest motives that leads men to art and science is escape from everyday life with its painful crudity and hopeless dreariness, from the fetters of one's own ever shifting desires.”

—Albert Einstein, for Max Planck's 60th birthday
“A finely tempered nature longs to escape from personal life into the world of objective perception and thought; this desire may be compared with the townsman's irresistible longing to escape from his noisy, cramped surroundings into the silence of high mountains, where the eye…
“…ranges freely through the still, pure air and fondly traces out the restful contours apparently built for eternity.

“With this negative motive there goes a positive one. Man tries to make for himself in the fashion that suits him best a simplified and intelligible picture…
Read 5 tweets
Radical Centrist, wrathful tantric deity 🇺🇦 Profile picture
Sep 23
“The extremely fit Australian scientist, who hiked, biked and surfed…had been bolstered by four doses of vaccine. Having spent nearly four decades studying how white blood cells…protect us from infection, he felt pretty safe about removing his mask.”

thetyee.ca/Analysis/2022/…
“Maybe it would be better to catch the ’rona and get it over with, now that I’m fully vaccinated?” he remembers speculating.

“After all, isn’t it just a cold in fully immunized people? And once I’ve had it, won’t I have acquired immunity that will mean I won’t get sick...?”
"But Omicron made a mockery of these popular assumptions.

"On May 26, Goodnow came down with a scratchy throat. Twelve days later his immune system had not cleared the virus. Then he got hit by congestive heart failure. He developed a chest cough and was breathless."
Read 7 tweets
Radical Centrist, wrathful tantric deity 🇺🇦 Profile picture
Sep 23
“Who could’ve predicted?!”

bloomberg.com/news/articles/…
“Brain and nerve conditions like Alzheimer’s disease and stroke are significantly more common among Covid-19 survivors than those who’ve never had the disease, according to a study of millions of patient records that raises alarms about the pandemic’s devastating aftereffects.”
“No one told us!” 🤡
Read 5 tweets
Radical Centrist, wrathful tantric deity 🇺🇦 Profile picture
Sep 23
web.archive.org/web/2022092300…
"The United States for several months has been sending private communications to Moscow warning Russia’s leadership of the grave consequences that would follow the use of a nuclear weapon, according to U.S. officials"
"Biden administration generally has decided to keep warnings about the consequences of a nuclear strike deliberately vague, so the Kremlin worries about how Washington might respond, the officials said, speaking on the condition of anonymity to describe sensitive deliberations."
Read 5 tweets

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