Zach Elliott Profile picture
Nov 1 13 tweets 3 min read
Imagine you are a male: you have a body plan organized around small gametes. You've always known you're male.

One day, you discover you have a hernia in your abdomen. You get it checked out by the doctor and they decide to do surgery. What they find shocks you and the doctors...
In your abdomen, they find ovarian tissue on your left side, and a partial Mullerian duct. They remove perform genetic analysis, finding you have a mixed karyotype: some of your cells are XX, but the majority are XY.
Scenario A: The doctors sit you down and tell you that you're not male or female. You're a hermaphrodite, a third sex.

You're naturally meant to be this way, and you do not need any medical intervention.
Scenario B: The doctors reaffirm to you that you're still male, and that this genetic disorder does not make you less of a male.

They explain to you how they need to remove the ovarian tissue and Mullerian ducts or they will likely cause health problems like infertility.
If you were in this person's shoes, which scenario is more reasonable to you?

Which scenario is more humane, compassionate, medically appropriate, and accepting of you as a person and of your future physical and mental health?
The truth is there are no human hermaphrodites. To tell people with developmental disorders, with atypical bodies, that they are not male or female is to strip them of their humanity and reinforce regressive stereotypes about what male and female bodies should look like.
[1] Rosenfield, K. (2018). Hermaphrodite. Encyclopedia of Animal Cognition and Behavior.
A hermaphrodite is an example of how the two sexes can be composed in one individual organism. Hermaphrodites are both sexes. They are third body type, but not a third sex.

Examples of this are common in plants, where a single plant might have both male and female flowers.
In humans, however, this term is clinically problematic and scientifically incorrect, as it does not accurately describe the person's body, sex, or condition while othering them as neither male nor female.
In reality, humans are either male or female. There are only two sexed pathways of development, and these pathways are mutually antagonistic: as the fetus develops down one path, the other path is inhibited.
In evolutionary biology, the term for this kind of system is gonochorism.
If you want to learn about what the two sexes are and their evolutionary origins, I recommend this piece.

Peer-reviewed literature throughout.
theparadoxinstitute.com/read/origins-o…
If you think the hypothetical case I described above is not realistic, check out this case study from the journal of Urology.

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More from @zaelefty

Nov 1
I was provided with a real case study in the journal of Urology that follows this hypothetical scenario almost exactly.

After a bike injury, a 15 year old male was found to have something astonishing in his abdomen…
A 15 year old male went to the doctor because of a bike injury that caused a ruptured testicle. They found ovarian tissue in his abdomen.
ncbi.nlm.nih.gov/pmc/articles/P…
They performed a karyotype and genetic analysis, and found that his karyotype is 46:XX, incredibly rare for a male, and that he is missing the SRY gene, essential for male sex differentiation, even MORE rare!
Read 10 tweets
Nov 1
Chromosomes are not sexes.

People with atypical chromosomal combinations are all male or female.

This is because the genes within the chromosomes still result in a body plan that produces small gametes (male) or a body plan that produces large gametes (female).
People with XY, XXY, XYY, XXYY, XXXY, and so on develop as males (barring genetic mutations).

People with XX, X, XXX, XXXX, XXXXX, and so on develop as females (barring genetic mutations).
theparadoxinstitute.com/watch/chromoso…
Males can even have XX (rarely) when the SRY gene translocates to an X chromosome in the father's sperm cells, and the fetus receives two X chromosomes, one with the SRY gene.
Read 4 tweets
Nov 1
First, "sexes" are phenotypes (body plans) that produce either small gametes or large gametes. There is no third role here, just two.

There are many ways the two sexes can be composed in organisms (gonochorism = one organism is one sex; hermaphroditism = one organism is both).
Second, "hermaphrodite" is a specific term in biology, now fallen out of favor in application to humans with developmental disorders because it is scientifically specious and clinically problematic.

Rosenfield, K. (2018). Hermaphrodite. Encyc of Animal Cognition and Behavior.
Third, a hermaphrodite is an example of how the two sexes can be composed in one individual organism. Hermaphrodites are both sexes. They are third body type, but not a third sex.

Examples of this are common in plants, where a single plant might have both male and female flowers
Read 4 tweets
Oct 27
On the difference between how sex is *defined* and how sex is *determined*.

It is important we separate these concepts to understand what male and female are and how they develop in the womb.

🧵
Sex is defined with respect to gamete type [1]. The male sex is the body plan that produces the smaller gametes and the female sex is the body plan that produces the larger gametes (ova) [2].
We know whether an individual is male or female by looking at the structures that produce (gonads) and release (genitalia) either gamete type. We look at whether the individual develops a body plan organized around small or large gametes [3].
Read 43 tweets
Oct 27
When you claim that people with disorders are not male or female, you strip them of their humanity.

Each disorder of sex development results in a male or female. You need to expand your boxes, not create new ones.
A woman with Congenital Adrenal Hyperplasia is considered not female by @interACT_adv. Why?

She has a full female reproductive system of ovaries, oviducts, uterus, cervix, vagina, and vulva. She experiences slightly masculinized genitalia due to overexposure to androgens. Image
A man with a full male reproductive system who happens to have XX, and not the typical XY, is considered not male by interACT.

Why? Image
Read 8 tweets
Oct 22
At the Nashville rally against child mutilation, the contrast between the trans activists and the other side was stark.

Trans activists filled with hatred, constantly cursing and yelling, while most people on our side were relaxed, wanted to have conversations, and smiling.
While @ChoooCole was speaking about her detransition story, the trans activists at the front were trying to drown her out with their sirens and megaphones while they called her names and yelled at her.
Meanwhile, she spoke calmly and clearly, and wasn’t at all phased by the loud activists, speaking the truth with compassion and grace.
Read 5 tweets

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