Sabina Vohra-Miller Profile picture
Nov 4 8 tweets 4 min read
The amazing @DrSamiraJeimy and I collaborated on a post because we are both tired of seeing the term ‘immunity debt’ being thrown around.

We also get into why we are seeing a record number of pediatric hospitalizations, so stick with us.
🧵(1/8) Immunity debt is not a thin!
So what is this ‘immunity debt’ concept?

Claims that lack of exposure to infections weakened children's immune systems, causing them to have severe infections.

There is no evidence that this is real.
(2/8) So what is this ‘immunity debt’ concept?  Immunity debt
In the absence of infections, the immune system does not lie dormant & weaken. We are constantly exposed to & co-exist with, trillions of viruses, bacteria & fungi.

Lack of infections does not weaken the immune system. But some infections, like measles and COVID-19, can. (3/8) So what is this ‘immunity debt’ concept?  Immunity debt
Pediatric hospitals are filled with sick children. What is going on?

While numbers of RSV & influenza are not higher than last yr at this time, MORE children are hospitalized than last yr. So higher proportion of children are coming to hospital with severe illness. (4/8) Pediatric hospitals are filled with sick children. What is g
Why is this occurring?

With removal of public health measures such as masking, many viruses are spreading widely. Given we have had a break from these, most of the population is susceptible & exposed again at the same time. But doesn’t explain the higher % of sick kids. (5/8) So, why is this occurring?  With the removal of public healt
One hypothesis: We know many viral infections, such as Covid and measles, can impact immunity downstream, even after mild infections.
Omicron spread widely among kids, & they may not have immune reserves to fend off subsequent viruses & infections as efficiently as before. (6/8) So, why is this occurring?  With the removal of public healt
To add, there is a massive healthcare staffing crisis. Healthcare workers are sick themselves, leaving healthcare due to being burnt out & underpaid. Without staff, hospital beds are in short supply.

Also, there is an ongoing shortage of fever reducing meds for children. (7/8) Why is this occurring?  Unfortunately, there is a massive he
Many are using this crisis to claim that public health measures have somehow impacted our immunity - THIS IS NOT A THING.

The public health measures we took in the last few years only helped reduce the burden of illness and did not in fact cause this crisis. (8/8) Why is this occurring?  Unfortunately, there is a massive he

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Sabina Vohra-Miller

Sabina Vohra-Miller Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @SabiVM

Oct 7
Bivalent Booster Dose:
Confused about what you should do?
Let's work through this together (1/7) Booster Dose  Confused abou...
Health Canada 🇨🇦 has now approved two bivalent boosters:

Moderna BA. 1 for 18+

Pfizer BA. 4/5 for 12+
(2/7) Health Canada has now appro...
Adults: Age >60, Immunocompromised or risk factors for severe illness

3+ months out of either an infection or last booster: get a bivalent booster now.
You can get either the Moderna BA. 1 OR Pfizer BA. 4/5 booster. The type of bivalent is less important (see last slide). (3/7) Adults: Age >60, Immunocomp...
Read 7 tweets
Aug 3
Lots of questions on infection control and disinfection. Here is a thread with some information.

First, general infection control of confirmed or suspected monkeypox. Isolate at home until rash ...
General cleaning and disinfection: Once recovered from monkeyp...
General cleaning and disinfection, continued: Order of cleaning:  Collect...
Read 6 tweets
Jun 22
New data: Reinfection was found to substantially increase the risk of death, hospitalization, and adverse health outcomes, making strategies preventing reinfection critical.
Summary 🧵 1/9 A key missing information h...
A recent study using the national health care databases of the US Department of Veterans Affairs compared people with first infection, reinfection or no infection.
Estimate risks and 6-month burdens of all-cause mortality, hospitalization and other adverse health outcomes. 2/9 A recent study using the na...
1- Reinfection resulted in additional risks of death, hospitalization and adverse health outcomes, including:
pulmonary, cardiovascular, coagulation and hematologic, diabetes, fatigue, gastrointestinal, kidney, mental health, musculoskeletal, and neurologic disorders. 3/9 1- Reinfection resulted in ...
Read 10 tweets
May 29
Lots of new data on Long Covid especially on vaccines and Omicron, so @LizMarnik and I once again teamed up to update our previous thread with recent studies.

Data current as of May 28th 🧵 1/9 Image
First up, Omicron specific data from UK ONS.

Double-vaccinated have ~50% lower risk after BA.1 vs Delta. But, even in triple-vaccinated, long Covid more common after Omicron BA.2 infections (9.3%) versus Omicron BA.1 infections (7.8%). 2/9

ons.gov.uk/peoplepopulati… The UK ONS released data on...
Next up: Lancet systematic review and meta-analysis.
Incidence of any long Covid symptoms was 56.9%, with most common symptoms being:
fatigue, muscle and joint pain, neurological, respiratory, mobility impairment and cardiac issues. 3/9

papers.ssrn.com/sol3/papers.cf… A Lancet systematic review ...
Read 9 tweets
Mar 13
We (@LizMarnik and I) have been asked many times to share Long Covid data, especially as it pertains to mild infections and neurological, cardiac effects. So we rounded up some recent data. 🧵 1/9 Image
Recent study assessed data from the US Department of Veterans Affairs.
Risk and 1-year burden of cardiovascular disease in survivors of acute Covid-19 are substantial. 2/9
nature.com/articles/s4159… A recent study assessed dat...Image
A recent study looked at the neurological impacts of Covid-19 infection in those aged 51-81. They found reduction in grey matter thickness, smell-related markers of tissue damage, reduced brain size & cognitive decline even in non-hospitalized. 3/9
nature.com/articles/s4158… A recent study published in...
Read 10 tweets
Feb 18
Deep dive on Novavax, which was just approved in Canada as another potential Covid-19 vaccination (1/7) Novavax is a subunit protei...
How it’s made (2/7) The genes that code for the...
Efficacy against variants, transmission (3/7) The clinical trials for Nov...
Read 8 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us on Twitter!

:(