Some thoughts on immunity debt vs. immunity theft. 🧵
First, I don't think the newly-coined (2021) term "immunity debt" is useful or well chosen. It is being used to refer to two very different ideas and is prone to confusion or equivocation. It doesn't help that one of those ideas is trivially true and the other is nonsense.
The version that is trivially true occurs at the population level. If a lot of people avoid infection in one season, then there will be less immunity in the population and larger numbers of susceptible hosts in the following season. Obviously.
This population-level version of "immunity debt" is very unlikely to actually account for what we're seeing right now, but at least it isn't nonsensical. "Debt" would not be the right term for this in any case.
The other version of immunity debt refers to the individual level rather than the population as a whole. It assumes that the immune system is like a muscle, and not using it against pathogens weakens it, making individuals more prone to severe infections.
The immune-system-as-muscle idea is a corruption of the (still debated) "hygiene hypothesis", which does NOT say that kids need to be exposed to *pathogens*. Let your kids play in the dirt, yes. Don't let them run around in a biohazard lab.
If we are stuck with the term "immunity debt", then the alternative idea to explain what is happening is "immunity theft" (same idea as "immunity robbery" coined by @FurnessColin).
The concept of "immunity theft" is simply that COVID infection (let alone repeated infections) may rob people of a working immune system, which puts them at risk for other infections.

How can COVID damage immune function? Here is a very good explainer:

thetyee.ca/Analysis/2022/…
This is not merely an academic debate. Proponents of immunity debt tend to be the same people who advocated against efforts to mitigate COVID in schools. They are now blaming remote learning and masks for surges in other viruses like RSV and flu in kids. They still oppose masks.
On the other hand, *IF* immunity theft is the cause, then letting COVID rip in schools was a disastrous idea, and we urgently need to prevent further immune-depleting infection with COVID and with other viruses that will now be having more severe effects than they usually would.
So which is it? Immunity debt or immunity theft? We don't know, and it's not either-or (at least, it could be the population version of immunity debt and/or immunity theft).
However, it has to be noted that immunity debt, even the non-ridiculous version, is not being used in a logically consistent way.

Do masks block RSV and flu so well that they cause immunity debt? If they work, why not use them now to keep kids out of hospitals?
If recommendations to wash hands are effective at stopping RSV and flu, why doesn't this cause immunity debt?

RSV and flu immunity do not last long, so how are "lockdowns" from 2 years ago still having this effect?
Also, many of the proponents of immunity debt have a terrible record when it comes to COVID claims.

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More from @TRyanGregory

Nov 14
*IF* there aren't actually atypically high rates of RSV in kids this year but there are far more hospitalizations, it seems there would be a few different hypotheses to consider (ASAP). 🧵
First, note that I am not seriously considering the individual-level, immune system is a muscle version of "immunity debt" here. It's nonsense.

Maybe there's a way to fit the population-level version of immunity debt to higher hospitalizations without more cases, though?
I think the two most plausible explanations would be that either the virus has changed and/or its hosts have changed. Specifically, virulence has increased (but not transmissibility), and/or host immunity has decreased/vulnerability to severe infection has increased.
Read 5 tweets
Nov 14
Observation on my time in COVID Twitter. Many minimizers have huge followings, but they get very little engagement on most of their posts. Maybe I just have more active/less bottish followers but it's like an order of magnitude difference despite my comaratively small following.
I also notice that it's my own explainer threads that get *by far* the most engagement. Rare direct interaction with minimizers does nothing whatsoever in that regard. Really, it's just always an unpleasant experience and I am happily mutually blocked with them all.
It's really only screenshots that show up in my feed or that people send to me that force me to read some of their most egregious statements. Otherwise, I do not want to see their threads, let alone descend into the comment pit.
Read 6 tweets
Nov 14
Someone credential-checked me about my posts on "immunity debt". How can an evolutionary biologist challenge MDs and immunologists?!?

Well...
First, it's not just me. There are many MDs, immunologists, and epidemiologists saying the same thing about so-called inmunity debt. I also reference what I post.
I spend an inordinate amount of time thinking and writing about standards of evidence given my field (evolution, "junk DNA"). I teach graduate-level philosophy of biology. And as an evolutionary biologist, I have a finely tuned "just so story" detector.

en.wikipedia.org/wiki/Just-so_s…
Read 10 tweets
Nov 13
The population level version of "immunity debt" (a term only used since 2021) isn't nonsensical like the individual level version is, but it is pretty clearly not consistent with how immunity to RSV and flu work, nor with epidemiological data from the past several years. 🧵
First, immunity to RSV is short-lived.

nature.com/articles/pr200…
Read 12 tweets
Nov 12
Immunity debt is all the rage in the US and UK. Meanwhile in Canada, there's plenty of the same narrative, but...
🧵

Great story by @ReporterTeresa featuring @FurnessColin and @DrSamiraJeimy on the dangerously misleading term "immunity debt".

globalnews.ca/news/9272293/i…
The National Post (a very right-leaning publication) considered whether COVID infection damages immune systems.

nationalpost.com/health/is-covi…
The was a detailed article on the idea of immune damage by COVID infection by @TheTyee.

thetyee.ca/Analysis/2022/…
Read 4 tweets
Nov 11
What is going on here?

Screen captures from today (going down) versus yesterday (going up). Wasterwater signal in Ontar...Wastewater signal in Ontari...
More specifically: ImageImage
To be clear, I'm not claiming anything untoward. I am simply unclear how the previous data can retroactively decrease. If it's an algorithm thing that can change like that week on week, maybe we shouldn't read very much into sudden changes in either direction.
Read 5 tweets

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