You have specific muscles for each different pathogen, and each of them is a bit different in how quickly/easily it gets stronger or weaker🏋️♂️
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For some bugs, once you've fought it once, your muscles are so strong against it they may never need another work out to fend it off (e.g. measles, smallpox)
For others, they get weak quite quickly, but get stronger again each time you fight it (e.g. RSV, Covid)
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The good news is, for many bugs you don't need to fight them at all to get stronger
That's what going to the gym is for 🏋️♂️
Vaccination! 💉
Your immune system gets practice fighting the bug, but without risk of you getting injured by it
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Does this mean you should go looking for fights?
No!
But it does mean if you (or many people) haven't fought a particular bug for a long time, your immune system might not be as ready to fight it off so quickly
Best bet is to head to the gym if you can
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Usual disclaimer that all our models of immunology are huge simplifications of an extraordinarily complex system we don't fully understand and there are always caveats etc
But as a simple model, the immune system as lots of muscles is actually surprisingly good
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Most existing evidence used to suggest efficacy of masks in young children is irreparably biased by systematic differences in masked vs unmasked populations
In some studies this is actually explicit, which makes it remarkable people consider it useful evidence
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The only study which controlled for regional differences was the preschool vs primary school study from Catalonia
The only difference was age, and no significant difference was found in masked vs unmasked cohorts suggesting lack of clinically relevant efficacy
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A request that before tweeting about “immunity debt” that you spent a few minutes reading *ANYTHING* published about it (your friends tweets don’t count)
Most people arguing about it are completely wrong about the basic premise