Q: Calcium infusion is contraindicated in digoxin-induced cardiotoxicity?
A) True
B) False
Answer: B
Despite the caveat that hypercalcemia may potentiate the cardiotoxicity of digitalis, calcium infusion is recommended to stabilize the cardiac membrane
In such a situation, calcium should be given slowly.
Calcium gluconate is preferred over calcium chloride, as chloride formulation contains three times higher elemental calcium than gluconate version.
Enchondromatosis, also known as Ollier disease, is a non-hereditary, sporadic, skeletal disorder characterized by multiple enchondromas principally located in the metaphyseal regions.
Ollier disease
non-hereditary, sporadic, skeletal disorder characterized by multiple enchondromas principally located in the metaphyseal regions.
Q: Continuous infusion and bolus intravenous loop diuretic overall carries same efficacy in heart failure (CHF) patients.
Beside, less chances of ototoxicity, what other advantage continuous infusion of loop diuretic may have over IV bolus in CHF patients?
Answer: It helps in maintaining sodium level
Continuous intravenous infusion maintains an effective rate of drug excretion, and inhibits sodium chloride reabsorption in the loop of Henle
IV bolus doses of loop diuretics, as expected are associated with higher and then lower rate of drug excretion, causing unreliable maintenance of sodium chloride hemostasis.