Thread by @Sthanu5

Diagnosis?

An otherwise healthy 45-year-old man

👉 4-week history of nonpainful discoloration of the maxillary gingiva

👉 no history of pigmented skin lesions

Intraoral examination showed areas of the gingiva that were black

👉 lesion was a pigmented macule, 1.5 cm by 4 cm in greatest dimension, with asymmetric and irregular borders and colors.

Histopathological examination revealed an infiltrating lentiginous melanoma
♦️

👉Oral melanoma is a rare neoplasm

👉 exposure to the sun is clearly linked to cutaneous melanoma

👉but is not clearly associated with oral melanoma

👉 underwent partial maxillectomy with 2-cm margins

👉 declined adjuvant radiotherapy and chemotherapy

**

No pathologic lymph nodes were found.

At follow-up 6 months after surgery, there were no signs of tumor recurrence.

♦️♦️

Gingival Melanoma

nejm.org/doi/full/10.10…

Differential diagnosis of pigmented lesions in the mouth, including characteristic features that help in diagnosis

researchgate.net/figure/Differe…