Alina Chan Profile picture
Jan 16 7 tweets 3 min read
New argument from natural #OriginOfCovid proponents:

The Wuhan-US scientists did not have a plan to make the pandemic virus. The experiments they proposed were clearly much more dangerous and unhinged.

Ok, suit yourselves.
The strongest hypothesis for a genetically engineered lab #OriginOfCovid is that scientists collected a new SARS-like virus that did not seem dangerous to humans and used this low-risk strain for clear gain-of-function experiments eg inserting a furin cleavage site in its spike.
This plan is literally written in the early 2018 proposal by the Wuhan and US scientists.

They would use "low risk" strains for cleavage site insertion. Nowhere in this section does it say they were going to use close relatives of known human pathogens.
documentcloud.org/documents/2106…
This makes it quite clear that the pandemic virus could have arisen from this research if the Wuhan scientists had embarked on their plan in the year and a half before the detected outbreak.
However, some natural #OriginOfCovid proponents are insisting that these scientists would not have used a low-risk virus but would have used their "poised for human emergence" close relatives to the 2003 SARS outbreak virus.
They're saying that this international team of highly expert virologists collectively agreed it was a good idea to enhance close relatives of a known human pathogen.
These natural #OriginOfCovid proponents have a much less generous opinion of these virologists than I do.

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More from @Ayjchan

Jan 14
To all the virologists and journalists asking for evidence that the pandemic virus may have been engineered in a lab, I think you missed this revelation in September 2021:
theintercept.com/2021/09/23/cor…
“Let’s look at the big picture: A novel SARS coronavirus emerges in Wuhan with a novel cleavage site in it. We now have evidence that, in early 2018, they had pitched inserting novel cleavage sites into novel SARS-related viruses in their lab.”
Put it this way, it is as if these scientists proposed to put horns on horses and 2 years later a unicorn shows up in their town. When they discover this unicorn and describe it to the public, they talk about every other feature except for the horn.
ayjchan.medium.com/the-evidence-f…
Read 5 tweets
Jan 13
This takes the 🍰
@Nature reporter asks Peter Daszak what he thinks of the cleavage site in the pandemic virus.
He says it enhances pathogenicity. Doesn't mention that he & Wuhan collaborators proposed putting these sites into SARS-like viruses in the lab.
usrtk.org/wp-content/upl…
@Nature On @TheLancet letter that condemned all conspiracy theories suggesting the virus did not have a natural origin... looks like the support from the chief editor was too strong and several of the authors did not manage to declare their COIs before the letter was published.
@Nature @TheLancet As early as May 2020 Daszak and friends had worried about being FOIA'ed and sought to evade it by using personal gmail addresses.
h/t @Rebecca21951651
Read 6 tweets
Jan 10
It's difficult to bet on whether the next pandemic will come from nature or a lab when you don't know what experiments are ongoing or will be carried out in hundreds of labs around the world.
It's difficult enough trying to find out what was happening in 1 lab in Wuhan #OriginOfCovid

Try scaling that to 100s of labs and predicting when and where lab-based outbreaks will occur.
Pathogen research today is very different than it was decades ago. Scientists are actively looking for pandemic potential pathogens and genetically modifying these live pathogens in the lab - labs often based in large metropolitan cities (and sometimes they have wet markets!).
Read 6 tweets
Dec 30, 2022
Zoonosis #OriginOfCovid proponents: "The virus was well adapted for not *just* human but tons of other animals!"

I'm not sure how this makes it any less likely that the virus came from a lab where bat viruses are pushed through primate & human cells, humanized mice & civets.
Dec 2017, virologist director of an OIE reference lab in China wanted to see scientists demonstrate in the lab that the human SARS strain can jump from bats to another animal, such as a civet. "If this could have been done, the evidence would be perfect.”
nature.com/articles/d4158…
Before the pandemic, Wuhan Institute of Virology: "We performed in vivo experiments in transgenic (human ACE2 expressing) mice and civets in 2018 and 2019 in the Institute’s biosafety laboratory. The viruses we used were bat SARSr-CoV close to SARS-CoV."
science.org/pb-assets/PDF/…
Read 7 tweets
Dec 29, 2022
“adaptation within humans was not needed for SARS-CoV-2 to spread”
- Proximal Origin & Friends, 2022, @ScienceMagazine

In other words, the pandemic virus was well adapted for humans.
@ScienceMagazine Proximal Origin & Friends also claim that the virus is well adapted for spreading in multiple species.

Yet, such a powerful virus left zero trace of its path and emerged in Wuhan out of all the hundreds of other cities in China and Southeast Asia.
@ScienceMagazine The scenario where the virus picked up its pandemic powers and immediately got on a non-stop high-speed train to Wuhan via an infected person or animal so as to leave no trace of its origin or journey is not impossible, but it makes for a very unlikely story.
Read 7 tweets
Dec 22, 2022
It would be a huge letdown if the coming US-based #OriginOfCovid investigation does not ultimately lead to more insight into how the pandemic started.

Finding the origin requires looking into places where evidence is likely to exist, not just people who pushed a nature origin.
Finding the #OriginOfCovid is challenging enough without dealing with the sideshow of some scientists who squashed public discussion of the lab leak theory. Honestly, it would only help them to paint the investigation as anti-science if they become the focus of the investigation.
An investigation should spend as much of their efforts as possible on gathering incontrovertible #OriginOfCovid evidence.

Without that, the chances of holding people accountable for trying to rule out a lab leak prematurely are low because they will keep insisting "no evidence".
Read 7 tweets

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