When someone asks me what I do, and I reply with something like ‘I’m an evidence synthesis researcher,’ they are usually having a hard time understanding that. It need not be this way. In fact, knowledge synthesis is something everybody does every day of their lives. [Thread] 👇
When we’re asking Google to list restaurants in the area, this is knowledge synthesis. And when we’re scrolling today’s news, this is knowledge synthesis too. The platforms do it in our stead. But when a physician is looking up options for treating a difficult patient? 2/8
Or when a financial analyst is gathering clues to making their investment decision? Or when an OSINT journalist is collecting evidence of a war crime? These would be knowledge synthesis too. However, the greater the negative impact of an adverse decision, the bigger the call. 3/8
The science of evidence synthesis has shown that methods matter. Aka metaepidemiology, it is surprising how poorly it has spread beyond health sciences. By studying and comparing different ways of retrieving and combining evidence, this science has learned how to do it best. 4/8
E.g., we now know the price of discarding potential sources of evidence. We have appreciated the importance of publishing a search and synthesis plan beforehand. Our language, though, as researchers, is oftentimes purely academic and prevents us from effectively reaching out. 5/8
Another problem that haunts us in evidence synthesis is our tools. A great many things in evidence synthesis are still done by hand, like screening papers and extracting data from them. Gosh, we have ChatGPT these days. 6/8
Finally, internal communication is also broken. Research waste, as they call it, is when different teams of scientists conduct largely overlapping studies either due to unfamiliarity with each other’s work or unwillingness to collaborate. Eventually, *lots* of effort is lost. 7/8
How can we put things together? How can we bring people together? All with an ultimate goal: Give the best possible answers to your search queries. Whoever you are, whatever you search for. As robust as COVID-NMA, as relevant as Google, as smart as ChatGPT. I’m working on it. 8/8

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More from @drzhelnov

Nov 12, 2022
It’s been two years since I started working on my Reproducible Systematic Subset query for #PubMed to power my knowledge synthesis appraisals at zheln.com, and look what I have found so far ⬇ 1/8
First and foremost, your regular PubMed searches you see when reading through evidence syntheses are fundamentally irreproducible ­– in part, at best. This is because they usually do not account for indexing dates – the issue I fixed in the RSSB 2/8
RSSB, being short for Reproducible Systematic Subset, is the same as PubMed’s regular Syst Rev filter (with both the older and newer versions combined) but tweaked for reproducibility: osf.io/z3ju7/ I.e., it gives you the same record set whenever you rerun the query 3/8
Read 8 tweets
Jul 12, 2021
1/ Both the Coldblooded and the City military practiced their initiation rituals. Among the former, an incision would be made in six strokes on the new adept’s left forearm by the most skillful local swordsman.
2/ The incision would heal leaving a lifelong scar that resembled a mirrored uppercase letter sigma half-doubled along the long axis.
3/ It was said that, should a Coldblooded betray their kind, the scar would open, and the traiter would die of unstoppable bleeding that could not be fixed even with surgery.
Read 6 tweets
Jul 12, 2021
1/ As the story tells, there were sometime the people called #Equiz. They lived in the country and did not know any technology. When firearms came to be, it somehow turned that many Equiz did not accept them.
2/ These have preserved the white arms as their weapon of choice and resisted technology ever since. Slaughter between the two factions has endured for many years, although the exact cause of it has now fallen into oblivion.
3/ With firearms came construction science, and its supporters founded the City, that has grown enormously with time. Surrounded with a titanic wall, the City is where maybe a half of all Equiz dwell.
Read 16 tweets

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