Sthanu Profile picture
Feb 7 9 tweets 3 min read
A 63-year-old man

👉developed purplish discoloration of his face after he underwent stenting and balloon dilation of the left CCA

What is the name of this finding?

Cutis marmorata

Harlequin syndrome

Livedo racemosa

Livedo reticularis

Telangiectasia
Shivering, sweating, and confusion developed immediately after artery dilation,

👉along with a left gaze preference, dysarthria, and hemiparesis on the right side of his body
*
Over the next 20 minutes, livedo reticularis developed on the left side of his face
An embolic protection device had been used during the procedure
*
Digital subtraction angiography

👉 patent left internal carotid artery

👉 an occluded distal left facial artery
*
No intracranial hemorrhage was seen on CT of the head
👉 transferred to the (ICU),

👉 MRI and angiography of the brain revealed

👉 infarctions in the territory of the lt middle cerebral artery with patent vasculature
*
An acute embolic stroke and cholesterol embolization syndrome of the face were diagnosed
An embolic protection device had been used during the procedure
*
Digital subtraction angiography

👉 patent left internal carotid artery

👉 an occluded distal left facial artery
*
No intracranial hemorrhage was seen on CT of the head
👉cholesterol embolization syndrome, atherosclerotic plaque contents from large-caliber arteries embolize to smaller arteries

👉 lead to vascular occlusion, inflammation, and end-organ damage
Livedo reticularis is one of the most common skin manifestations of the syndrome
♦️
👉 received supportive care in the IC

👉 livedo reticularis resolved 1 week after the event

👉 neurologic deficits persisted at the time of his discharge from the hospital 2 months later.
Livedo reticularis
Cholesterol Embolization Syndrome after Carotid-Artery Stenting
nejm.org/doi/full/10.10…

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More from @Sthanu5

Feb 8
A 72-year-old man

👉presented to the emergency department with an 11-hour history of periumbilical abdominal pain and inability to pass flatus

What is the finding?

What is the most common underlying cause? Image
Answer:

Portal Venous Gas

Bowel ischemia
Portal venous gas is most commonly associated with bowel ischemia

👉 poor prognostic sign in patients with that condition
Read 6 tweets
Feb 8
A 55-year-old, nonsmoking woman

👉without underlying disease

👉productive cough, dyspnea, night sweats and 4 kg weight loss

Diagnosis? Image
Chest radiography and computed tomography showed a miliary pattern of many small nodules throughout all lung fields Image
differential diagnoses included

tuberculosis

fungal infection

malignant disease
Read 6 tweets
Feb 8
Which of the following commonly prescribed drugs has the narrowest margin of safety?

A.
Alprazolam

B.
Lithium

C.
Simvastatin

D.
Sildenafil Image
Answer:

B, Lithium Image
Drugs with a narrow margin of safety must be carefully titrated to find the effective but nontoxic dose.

Even when used alone, these drugs may have serious adverse effects. Image
Read 7 tweets
Feb 8
What is the diagnosis?

Deep venous thrombosis

Necrotizing fasciitis

Chemical burn

Scleroderma

Digital ischemia Image
A 56-year-old woman

👉 diabetes mellitus complicated by retinopathy and mild nephropathy and managed with glyburide (glibenclamide) and metformin

👉reported having abdominal pain and fever for the past 48 hours
On admission she was short of breath, hypotensive, and in shock.
*
WBC 25,900

👉 disseminated intravascular coagulation
Read 9 tweets
Feb 7
What is the sign here? Image
Shmoo Sign:

Appearance of a prominent, rounded left ventricle and dilated aorta on a plain AP chest radiograph giving the appearance of Shmoo.Indicative of left ventricular enlargement.

References: radiopedia.com Image
Appearance of a prominent, rounded left ventricle and dilated aorta on a plain AP chest radiograph giving the appearance of Shmoo, a fictional cartoon character in the comic strip Li'l Abner in the 1940s.

This sign is indicative of left ventricular enlargement. Image
Read 4 tweets
Feb 7
How would a nurse evaluate the effectiveness of a patient being treated with filgrastim (Neupogen)?

Monitor the hemoglobin

Monitor the WCB count

Monitor potasium levels

Monitor blood glucose Image
Answer

Monitor the WCB count Image
Neupogen® (filgrastim)

👉 used successfully for cancer patients to stimulate the growth of the white blood cells, making patients less vulnerable to infections

👉 it is expected to help patients who have bone marrow damage from very high doses of radiation in much the same way
Read 7 tweets

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