One of the skeletal abnormalities of AHO—“knuckle, knuckle, dimple, dimple” appearance of the hand resulting from premature closure of the epiphyses—is known as knuckle-dimple sign or Archibald’s sign
It is a feature of Albright's Hereditary Osteodystrophy (AHO) phenotype known to be associated with both pseudohypoparathyroidism (PHP) as well as pseudopseudohypoparathyroidism (PPHP).
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👉 refers to sparing of the mid scapular region in patients having prurigo nodularis with neurodermatitis as they are unable to reach the region for scratching.
Prurigo nodularis
👉 ch disorder of the skin that is classically seen as multiple, firm, flesh to pink colored papules, plaques and nodules
👉commonly located on the extensor surfaces of the extremities.
The lesions are very pruritic and can occur in any age group