Thread by @FavaleAbs

If "the science is settled"...🧵

https://twitter.com/glaad/status/1625854419102478338

2/ Why did Sweden conclude, after a systematic review of evidence, that the risks of gender-affirming treatment for youth outweigh the possible benefits?
socialstyrelsen.se/globalassets/s…

3/ Why did Finland issue new guidelines prioritizing psychotherapy after a systematic review found that the evidence for pediatric transition is “inconclusive”?
palveluvalikoima.fi/documents/1237…

4/ Why did this 2019 Finnish study conclude that “medical gender reassignment is not enough to improve functioning and relieve psychiatric comorbidities among adolescents with gender dysphoria?” tandfonline.com/doi/full/10.10…

5/ Why does France urge “great medical caution” given the “undesirable effects” and “serious complications” gender-affirming care can cause?
academie-medecine.fr/la-medecine-fa…

6/ Why did the UK’s Cass review conclude that “evidence on the appropriate management of children and young people with gender incongruence and dysphoria is inconclusive both nationally and internationally,” noting in particular lack of long-term data? cass.independent-review.uk/publications/i…

7/Why did the Obama admin conclude in 2016, after an evidence review, that the “clinical evidence for gender reassignment surgery was inconclusive?” What ground-breaking studies have been issued since that time that show conclusive positive results? cms.gov/medicare-cover…

8/ If the science is settled, why does every single systematic review of the existing evidence base conclude that the science is *not* settled?

9/ Why did Tordoff et al 2022 fail to show any meaningful improvement in mental health outcomes among the PB/GAH treatment cohort—while reporting the opposite?

10/ Why did Chen et al 2023's study protocol state eight key measures to track--only to have gender dysphoria, trauma symptoms, self-injury, suicidality, body esteem, and quality of life disappear from the published study? Why hide those results?pubmed.ncbi.nlm.nih.gov/31290407/

11/ And why, if treatment is supposed to reduce suicidality, did the Chen et al treated cohort have an alarmingly high suicide rate *after commencing treatment* and despite the fact that severe psychiatric problems were an exclusion criteria? drive.google.com/file/d/1e-0vOr…

12/ Why did a correction to Bränström & Pachankis 2019 find “the results demonstrated no advantage of surgery in relation to subsequent mood or anxiety disorder-related health care visits or prescriptions or hospitalizations following suicide attempts?"
ajp.psychiatryonline.org/doi/10.1176/ap…

13/ If the science is settled that these treatments prevent suicide, why are there multiple, long-term studies that consistently show increased suicidality after transition? 2011 Dhejne et al, 2016 Virupaksha et al, 2021 de Blok et al...

14/ Why did the findings of the original Danish study fail to replicate in the UK? And why were the negative results hidden from the public for six years?
ncbi.nlm.nih.gov/pmc/articles/P…
tandfonline.com/doi/full/10.10…

14/ Why is there *not a single study* that can provide high-quality evidence of a causal relationship between pediatric transition and clinically significant, long-term improvements in mental health?

15/ And how can *increasing social acceptance* be the sole explanation for the surge in pediatric transition, while *lack of social acceptance* is the sole explanation for elevated suicide risk? Could it be that there are, in fact, other explanations at play?

16/ If the science is settled, why are you so afraid of these questions?