Ulrich Elling Profile picture
Mar 9 4 tweets 3 min read
🇦🇹 Representative genomic surveillance of SARS-CoV-2 in Austria week 10, 2023 across most regions. Current analysis includes samples until March 3rd allowing faithful nowcasting. A collaboration of #AGES @agesnews and @IMBA_Vienna/@oeaw.
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Based on reported case numbers at least, XBB.1.5 appears to have passed it’s peak. This trend is less obvious but also seen in wastewater, see page 10 in the link below:
corona-ampel.gv.at/sites/corona-a…
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Extrapolated absolute case numbers also illustrate the reduced growth. Truly a good sign if the trend holds! Other countries are presumably a bit behind with XBB.1.5, so important to see the trend changing. In Austria relative share of XBB.1.5 is at ~69% currently.
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The relative share of EG.1 continues to grow within the XBB lineages. And the first case of XBB.1.16, the fastest lineage by far currently, was also detected in Salzburg once.
PS: Three more weekly updates to come after this one.
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More from @EllingUlrich

Feb 24
🇦🇹 Representative genomic surveillance of SARS-CoV-2 in Austria week 8, 2023 across all regions. Current analysis includes samples until February 15th allowing faithful nowcasting. A collaboration of #AGES @agesnews and @IMBA_Vienna/@oeaw.
1/4 Image
XBB.1.5 continues to grow and makes up ~60% of cases now in nowcasting. Shown here are the relative fractions within the total reported (!) cases.
2/4 Image
In quantitative sewage monitoring the situation looks very different. The level of detected SARS-CoV-2 appears to be near the values of last year at this time. Infection risk is thus very high currently and hospitalizations are also increasing.
3/4
abwassermonitoring.at/dashboard/ Image
Read 4 tweets
Feb 17
🇦🇹 Representative genomic surveillance of SARS-CoV-2 in Austria week 7, 2023 across all regions. Current analysis includes samples until February 8th allowing faithful nowcasting, sample numbers dropping though. A collaboration of #AGES @agesnews and @IMBA_Vienna/@oeaw.
1/6
Current significant growth in incidence is almost exclusively due to XBB.1.5, that reached >50% of cases now.
2/6
Only very few other lineages continue to show growth in absolute numbers as visualized when extrapolating shares of lineages to absolute reported numbers.
3/6
Read 6 tweets
Feb 15
Eine Initiative, das gesellschaftliche Corona-Trauma aufzuarbeiten, wie Kanzler Nehammer anregt, wäre ja prinzipiell sehr begrüßenswert.
Zuerst sollten wir aber diskutieren, daß das Virus jeden einzelnen und uns gemeinsam an die Grenzen gebracht hat.
1/
derstandard.at/story/20001435…
Deshalb sollten die individuellen und gemeinsamen Be- und Überlastungen verarbeitet werden. Wer wurde wann warum über die Maßen belastet? Auch wer hat wann wo ungerecht profitiert?
2/
Aber nochmals: Die Ängste, die Belastungen, das Leid, das die Pandemie verursacht hat, ist vor allem eine Naturkatastrophe und nicht die Schuld von irgendjemand. Gegenseitige Schuldzuweisungen machen es nicht viel besser.
3/
Read 18 tweets
Jan 13
🇦🇹 Representative genomic surveillance of SARS-CoV-2 in Austria week 2, 2023 across all regions. Current analysis includes samples until January 5th allowing faithful nowcasting. A collaboration of #AGES @agesnews and @IMBA_Vienna/@oeaw.
1/5
The variant situation for Austria changed dramatically between the years. While we had a swarm of lineages growing in numbers until Christmas, it is now just one lineage showing growth: XBB.1.5.
2/5
XBB.1.5 is a descendent of the strongly immune evasive recombinant XBB that now acquired a mutation improving binding to the ACE2 receptor on human cells and thereby infectivity. It is observed across Austria now. Nowcasting predicts it to be currently at ~8%.
3/5
Read 5 tweets
Dec 16, 2022
🇦🇹 Representative genomic surveillance of SARS-CoV-2 in Austria. This is our analysis run number 100, so I would like to start by thanking the entire SARSeq team. One hundred successful analysis rounds straight is an amazing achievement, congratulations to everyone!
1/ Image
With @LCochella and @yelagandula_ram we initiated the task of nationwide surveillance of SARS-CoV-2 in an academic setting in response to the Alpha variant. A great collaboration between #AGES @agesnews, @IMPvienna and @IMBA_Vienna/@oeaw. And a big responsibility!
2/ Image
This collaboration of health authorities and academia showcases the innovative power and value of academic institutions that stepped in in response to the pandemic. Globally such solutions were rather the rule than the exception, so big shoutout to all my colleagues worldwide!
3/
Read 13 tweets
Nov 24, 2022
Important work on the wild reservoirs of SARS-CoV 1 and 2 and a new SARS-CoV-SARS-CoV-2 recombinant in a paper that just went online summarized here 🧵:
biorxiv.org/content/10.110…
1/11
Yunnan Province at the southern tip of China is a hotspot for bats and bat viruses. Closest relatives of SARS-CoV as well as SARS-CoV-2 are found here and different bat species are living in caves together.
2/11
In this important work, researchers analyzed 149 bats individually to study what virus they carry and found 41 different ones, 70 bats were positive for at least one virus (47%), amongst them 1.5 viral species were found on average per individual.
3/11
Read 11 tweets

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