There is finally an update on the #Marburg situation in Equatorial Guinea:
Total now stands at 9 confirmed and 20 probable cases. A month ago there was only one confirmed case.
27 of these cases have died (including all probable and 7 out of 9 lab confirmed cases)
13 March: two positive tests from Kié-Ntem province
15 March: a case from Litoral province tests positive
„The two provinces (Kié-Ntem and Litoral) are located in different parts of the country, about 150 kilometers apart“
18 and 20 March: 3 more cases confirmed from Litoral province.
20 March: 2 more laboratory confirmed cases reported from Centre Sur province.
The situation looks very much not under control, I‘m sorry to say:
„The wide geographic distribution of cases and uncertain epidemiological links in Centre Sur province suggests the potential for undetected community spread of the virus.“
„All three affected provinces have international borders with Cameroon and Gabon. Cross-border population movements are frequent, and the borders are very porous.“
Clearly a risk of spread to other countries though no cases have been reported outside Equatorial Guinea so far.
As someone who mostly covers #globalhealth, I find it remarkable that the closing statement of #HGESummit specifically addresses "Equitable access for somatic human genome editing".
So let me quote that part here in full:
"As interventions based on somatic genome editing become more widespread, a commitment to equitable, financially sustainable, and accessible treatments becomes more urgent."
"In many cases, costs and infrastructure needs of current gene therapy treatments are not manageable for either patients or healthcare systems."
After three days of talks at the #HGESummit, Robin Lovell-Badge now reading closing statement:
"Remarkable progress has been made in somatic human genome editing, demonstrating it can cure once incurable diseases. To realise its full therapeutic potential, research is needed to expand the range of diseases it can treat, and to better understand risks and unintended effects
"The extremely high costs of current somatic gene therapies are unsustainable. A global commitment to affordable, equitable access to these treatments is urgently needed."
Session now on "Are there compelling reasons for heritable human genome editing?" at #HGESummit. Ephrat Levy-Lahad giving an overview of global regulation first:
„There's not a single country where heritable genome editing is currently permitted.“
This probably does not reflect universal opposition to the technology, but rather current limitations, she says, „in particular, the realisation that there is still a major issue of safety and clinical application would not take place until these issues are resolved“
But that means we have an opportunity now to discuss what happens if safety were achieved, she says. „I realise this is a big if, but we need to start thinking about it.“ #HGESummit
@TheCrick Patient groups were much more active around gene editing five, six years ago, says @MBoudes. Says he does not know why. "I hope to find the answer from the discussion with my fellow speakers and also from the audience." #HGESummit
@TheCrick@MBoudes "The reason I ended up in patient advocacy and sitting here is unfortunately a very personal one", says @BettinaRyll. She was working as a scientist when her husband was diagnosed with melanoma. "we were told ... I'm sorry, it is cancer. And there is nothing we can do for you."
In London at @TheCrick to attend the Third International Summit on Human Genome Editing. Should be an interesting three days. #HGESummit
@TheCrick "China has considerably improved its legislation and regulations regarding life sciences, including human genome editing, over the last several years", says Yaojin Peng at #HGESummit.
@TheCrick China is increasingly approaching governance of biotechnology research from a precautionary perspective, he argues.
And: "China's legislation regarding human genome editing is basically in line with internationals standards." #HGESummit
Vor zwei Wochen habe ich mich in Berlin mit @jeremyfarrar getroffen. Er war auf dem Weg zur @MunSecConf und wir haben über Covid und H5N1 gesprochen und darüber, was Terroranschläge und Pandemien verbindet…
Zu Covid:
Farrar sagt, er trage in öffentlichen Verkehrsmitteln noch immer Maske. „Aber es stört mich nicht, dass die meisten anderen Menschen das nicht tun.” Im Großteil der Welt sieht er keine Notwendigkeit mehr für Einschränkungen.
Die Welt darf aber nicht vergessen, dass das Virus auch noch einmal eine böse Überraschung bereit halten könnte, sagt Farrar. Das Virus müsse darum weiter überwacht werden. „Leider haben viele Länder die Überwachung eingestellt und ich denke, das ist ein Fehler.“