Another #VaccineConversation about the COVID vaccines - what we are using here in UK and where we might go next. First mRNA vaccines- many of us have had these now and @britsocimm made this brilliant infographic of how they work
They are super easy to adapt quickly and can be made using information for more than one variant- so last autumn they used info (mRNA) from a newer COVID variant and the original ancestral strain to evoke an immune response
They are not actually a new technology and have been tested in labs for years with, at the time of COVID human trials for a variety of infections nature.com/articles/d4158…
However they have been met with some suspicion but they have been robustly tested, don;t contain harmful chemicals, cannot permanently alter your DNA. NB The risks of being infected with COVID are significantly worse than risks of vaccination independentsage.org/demystifying-a…
And there is a lot of excitement about the future potential because they can be used in lots of other diseases doi.org/10.1038/s41591…
But these vaccine types are not the only approach and there is interest in vaccines that may be more robust against covid which I wrote about here theconversation.com/covid-inhalabl…

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More from @sheencr

Mar 30
Happy #VaccineConversations day today. A short 🧵 on evolution of vaccine development.. @britsocimm
We may not always appreciate those shots in the arm we get against disease such as flu and covid but the science behind them and the story of how vaccines developed is fascinating
The developments in vaccination came in answer to a terrible often lethal disease- smallpox. This disseminated country’s population and survivors were scarred and even blinded.
Read 9 tweets
Mar 28
For those who say disinformation about covid vaccines matters less now cos many are vaccinated (and that is a whole debate in of itself) this affects all vaccine trust
Just sitting in a research talk now showing massive drop off post covid in flu vaccine uptake in poorer deprivation areas
Also been data showing lower uptake of mmr etc e.g nuffieldtrust.org.uk/resource/vacci…
Read 4 tweets
Mar 15
Today is #LongCovidAwarenessDay
LongCovid is a condition comprising often severe symptoms that can affect many different organs. It occurs following infection with SARS-CoV-2. Symptoms include cardiovascular, respiratory, neurological as summarised by @EricTopol and colleagues
Its REALLY common. Estimates vary - it occurs in at least 10% of Covid 19 infections and around 65 million individuals worldwide are estimated to have Long Covid.
It can occur irrespective of severity of the initial disease and any person of any age can be affected. The highest percentage of diagnoses are between the ages of 36 and 50 years but even children are affected. longcovidkids.org
Read 8 tweets
Mar 1
Our data using Britain Breathing citizen science app is showing that people in urban areas have worse hay fever and asthma symptoms. The work has a long journey to reach this stage 🧵
nature.com/articles/s4159…
@CarolineEJay @annannfryingpan @lankymanky @LydiaBeckerIII @UoMEngage
I was working with non native English speakers exploring research and questions around parasite infection. The groups often asked why there were so many allergies. My son too developed asthma and all this made me curious to start looking at this topic more.
Conversations with @britsocimm @RoyalSocBio opened up the possibility of taking a citzien science approach but this was new to me so I sought advice from the brilliant @erinmaochu. Inspired and emboldened by Erinma i then talked with a brilliant cross-disciplinary researchers…
Read 10 tweets
Feb 24
A certain cardiologist and fox pundit and taking nonsense about vaccines and miscarriage. This has been debunked countless times. There is no evidence of the vaccine causing miscarriage. However covid can cause serious issues for babies.
I urge you to look at the excellent resources by @VikiLovesFACS - her tweets and resources she has collated are outstanding drive.google.com/file/d/1_wHIYX…
And also the @MidwivesRCM have an excellent resource rcm.org.uk/coronavirus-hu…
Read 4 tweets
Jan 11
A brief 🧵on the term ‘immunity’ - this is perhaps misunderstood by many and exploited by others.
Immunity refers to the development of memory immune cells -T and B cells that have encountered a pathogen (virus,bacteria,funghi,parasite) and have gone through the necessary programming to be able to react to that pathogen should they meet it again
Memory cells are extremely long lived. For example survivors of the 1918 flu pandemic still had evidence of memory B cells over 80 years after they had been infected
Read 7 tweets

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