Now it only took the first slide (next tweet) to draw my full attention, and mean that I will be catching up with recordings later. This raises VERY important questions for #OBAnes in light of recent #SOAPAM2023 chats
Neuraxial anesthesia as a sedative…
Sensory deafferentation dependent sedation - an example of a full stomach being sedated that #OBAnes do routinely @VeenaGraffMD (oh wait it gets better) #RAUK23#SOAPAM2023
Patient age and sensory block level significantly affect relationship between propofol Ce and sedation (I added the graphs from Roh et al’s study). Regional techniques dynamically reduce neural traffic. #RAUK23#SOAPAM2023
Regional techniques including neuraxial reduce neural traffic such that the brain stem SLOWS DOWN, which in turn has a knock on effect on the effects of sedatives like propofol. (@Chronotrope feel free to contribute - it was 330am and 🤯 as new information to me at least) #RAUK23… twitter.com/i/web/status/1…
Decreasing neural traffic and decreasing hypnotic dose. When walking a tightrope of consciousness, sedatives can add a light wind. In the setting of regional/ neuraxial, it’s a thunder storm - more likely to fall off! @VeenaGraffMD@HofkampMichael@emilysharpe#RAUK23#SOAPAM2023
pEEG calibration is more complex than we like to think. There is NO distinct number separating conscious from unconscious. Significant overlap exists! #RAUK23
Different drugs do different things. Classic EEG changes with anesthesia and sedation. Some familiar patterns. #RAUK23
BIS number and EEG morphology disconnect. pEEG identifies anesthesia and suppression. Have you ever had a patient SO suppressed that EEG on reads ECG? (@AnaSjaus and I have seen this at TIVA GA section). pEEG can reduce unintended anesthesia.
Of note (especially with recent #OBAnes discussions @VeenaGraffMD) other agents do different things. The anesthesiologist is the integration engine. #RAUK23
Dr Brian Bateman moderates the #SOAPAM2023 Gertie Marx Research Competition. #OBAnes
Number 1. @LilianeErnstMD presents The ED90 of Hyoerbaric Bupivacaine for Cesarean Delivery in Super Obese Patients #OBAnes#SOAPAM2023
Background. Pre-pregnancy obesity increasing across racial groups. A large percentage in grade 3 obesity, racial differences. Super Obese patients more likely to have cesarean section. High block was more common in BMI > 50. #SOAPAM2023#OBAnes
The allergist team are ready and waiting for your referral, poised to leap into action with different testing modalities. When would they do a drug challenge? To test cross reactivity, exclude allergy and confirm diagnosis #RAUK23
Skin testing (a positive latex allergy) includes a negative spot (saline to rule out dermographia) & a positive histamine spot to check for antihistamines in system)
Intradermal testing uses low dilutions for specific drugs. Here a 1:10,000 dilution of sugammadex illicited a… twitter.com/i/web/status/1…