A woman in her 30s with no past medical history presents with acute dyspnea, fever and a non-productive cough.
She has no sick contacts or recent travel. She is not on home medications and smokes cigarettes and occasionally vapes.
What is the predominant imaging abnormality?
She is found to have diffuse bilateral patchy ground-glass opacities with some interlobular septal thickening.
She has escalating oxygen requirements and was initially started on broad-spectrum empiric antimicrobial therapies
Her initial serum infectious work-up and RVP are negative. She denies any new occupational or home exposures. She does not appear to respond to antibiotics after 72 hours.
What is your leading differential at this time?
You proceed with a bronchoscopy with BAL to obtain a cell count and diff and culture data.
Which cell type would confirm your leading diagnosis?
You start empiric steroids (prednisone 60 mg daily) given concern for acute eosinophilic pneumonia. Within 48 hours she is weaned off HFNC and was discharged home on D7 on room air with close pulmonary follow-up.
She was amenable to tobacco cessation therapies and was followed closely outpatient with tapering of her steroids over 4 weeks.
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For "#RadiologyRounds" today, we won't be looking at any imaging, but we'll be looking at some vent wave forms and examining dysynchrony! This is a re-booted @david_furfaro Tweetorial.
I hope you enjoy and this is an open invitation for all dysynchrony waveforms!🫁🚨
A 40s M is intubated for ARDS. In order to maintain lung protective ventilation, he was on high does of propofol, fentanyl and midazolam. His sedation is being weaned slightly now, and the RN calls for vent dysynchrony. His ventilator looks like this
Before delving into the type of dysynynchrony and management, based on these waveforms what is actually happening? Note: when we say “exhales” or “inhales” I am referring to the mechanical, vent-driven breaths
Wow great thoughts by everyone on this case! For a reminder, a man in his 40s has progressive dyspnea and fatigue after a mild COVID infection and this CT scan:
Many of you rightly pointed out
🔹Septal thickening
🔹Reticular infiltrates
🔹Pleural involvement and effusions
🔹GGOs
All of these features are present. What is strikingly prominent is the reticulation and septal thickening. With this we always want to think about the lung lobule and its features:
Prominent reticulation can be septal thickening from fibrotic processes causing honeycombing (UIP pattern as in IPF) or with fibrotic NSIP / OP .
This can also be due to diseases that impact the lymphatic system. These generally cause less distortion of the lobule structures
A patient with pneumonia and ischemic cardiomyopathy was intubated for hypoxemic respiratory failure. They’ve improved and been on minimal vent settings, but repeated SBT failures
What breathing pattern is happening with the patient on pressure support 5/5?
We are excited to bring you another #RadiologyRounds which applies some of the knowledge from our most recent episode.
A patient in her 20s presents with shortness of breath at rest, left sided pleuritic chest pain and increase in cough and sputum production.
In addition to underlying parenchymal disease, what other abnormality do you see?
She is presenting with a 1.5 cm left pneumothorax. You can see lucency representing air in the pleural space. There are a lack of blood vessels or lung markings extending to the periphery and you can see the visceral pleura.
Our last few #PulmPEEPs radiology rounds have been CT-centric, so today we’re going back to some useful CXR signs!
Our patient is admitted to the ICU for hypoxemia and has poor compliance and low P:F ratio after intubation
2/ On reviewing the CXR there is concern for lobar collapse in the ________ lobe
The patient has RUL collapse and a Reverse S Sign or Golden S Sign raising concern for a mass or space occupying lesion obstructing the right upper lobe bronchus
Welcome to the first #PulmPEEPs radiology rounds of 2022!
You are concerned for diffuse alveolar infiltrates on chest x-ray and you obtain a CT chest for better parenchymal visualization. How would you best describe the imaging findings on CT chest?
The CT chest shows bilateral areas of ground-glass opacities with both intralobular and interlobular septal thickening.