Jean Fisch Profile picture
Jul 20, 2023 18 tweets 6 min read Read on X
I continue to see talks of high unexplained excess deaths in England and Wales in S1 2023

This is NOT confirmed by data by occurrence date and is an artefact resulting from
/ reporting by registration date
/ policy of only registering deaths once cause is assigned

THREAD Image
Just to make my point crystal clear

The S1 2023 deaths by registration date excl covid are POSITIVE and high which signals lots of unexplained deaths

Yet, when using deaths by occurrence date (as one should), the same total is NEGATIVE. So in fact no/few unexplained deaths

1/ Image
If you think that this effect is just the result of the fact that I used the ONS baseline which is not a proper choice

The same conclusion holds true when using the approach that CMI proposes (ie based on 2019 mortality rates and adjusted for population development)

2/ Image
Why is this so? Because of TWO main factors

Factor 1: The huge wave at the end of 2022 led to an unusually high amount of 2022 deaths being registered in 2023 (I estimate 7k more than in previous years)

So deaths by registration inflate the true death toll in 2023

3/ Image
But that's not the end of the story: There is a 2nd more pernicious factor playing here

E+W is unique in that it only registers deaths once cause of death is assigned

Other countries register unclear deaths under a temporary ICD code and correct it once the cause is clear

4/
The weakness of the E+W system is that deaths that require to go through coroners (as is often the case in younger age bands) can take a year or more before they get registered

So the death data by occurrence date takes much longer to be complete

5/
Just to illustrate the magnitude of the issue: I found some data by age and occurrence for England

It shows how, at the end of May 2023

/ the last 18 months of the 15-44 data
/ the last 6-9 months of the 45-64 data

were essentially materially incomplete

6/ Image
Here another way to show this based for the 15-44 age band

In 2022, ONS shared the same dataset by occurrence for deaths registered up to May 2022

If you compare it with the dataset with deaths registered up to May 2023, you see how the data diverges over the last 18 months

7/ Image
The registration date for many deaths in younger age bands will be MUCH later (up to 18 months) than death occurrence

This means that the data by registration date will not reflect the timely pattern of the deaths in these age bands (compare blue and black line)

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But as, I explained yesterday, this has other consequences: If, as is likely in a pandemic, there are MORE deaths going through coroners, then X months later, deaths by registration will see a (fake) increase

And this is what I suspect is currently happening in 2023 as well

9/
Unlike previous years, there were much more deaths registered in May-Jun 2023 than occurred

(the deaths occured is the result of an estimate made by ONS which corrects for lag and is quite precise at top level)

10/ Image
As I show here, this means that almost all the excess mortality seen in the data by registration date in May-Jun 2023 is the result of deaths that occurred before May

11/

It took me quite a while to understand why deaths by registration were so off vs. the actual situation

What happens is that registration-based data is quite robust if one year is like another (as it was pre-pandemic)

12/
However, if, as is the case in a pandemic, there are "one-off" and lots of unusual events, constraints on registration capacity, etc., the data by registration date starts to be driven by noise instead of underlying death occurrences

And this what we are currently seeing

13/
So deaths by registration date are currently not suited for analysing excess mortality in England+Wales as it is affected by

/ much higher than usual spillover from 2022 to 2023

/ likely catch-up of past occurrences only registered now

/ timely noise in younger age bands

END
@AdeleGroyer (by significant, I mean 1-2% which is essentially within band of uncertainty)

That's why I was getting more and more concerned about the difference of message between registration date data and occurrence one

But happy to be proven wrong, as you know! :-)
@AdeleGroyer And of course, just to be clear: no topline excess does not mean no excess: It could well be that there is negative excess in older age bands and more positive in younger ones

Here the data from the 65-84 which is pretty complete up to Mar 23 and there is no excess before covid Image
NB: I put this thread on hold until I clarify seemingly contradictory elements
/ I find the ONS modelled deaths remarkably accurate
/ However, they imply an unrealistic shortening of the death registration lag

More to follow once I understand what's happening Image

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More from @Jean__Fisch

Aug 10, 2025
A little example to show well the assumptions of the Ioannidis "Lives Saved" study fit reality
- Take its IFR estimates
- Get the US MCOD covid deaths from CDC up to 14/11/20
- Calculate infx up to 31/10/20
Result? The study estimates that the US infx rate was 62% by 31/10/20😀 Image
Now I took end October 2020 out of a reason: There are two sera studies for the US at that date
a) CDC: 8%
b) another study: 11% (side comment: actually 5% but then doubled for serareversion which is far too much)

thelancet.com/journals/lanam…

academic.oup.com/cid/article/74…
Of course, the covid rates are for the world and not the US

BUT

The main factors potentially affecting the IFRs would be:

- level of comorbodities (would push US IFR up vs world)

- Quality of healthcare access (would push US IFR down vs the world)
Read 6 tweets
Jul 28, 2025
I did the following:
- I took the sera studies considered as good by Ioannidis in his paper on IFR from 2023 for West Europe (incl DE/FR/SP/IT/PT/AT ...)
- I matched that with the info I have on covid deaths per certificate

Result? Covid IFR was >1% in Western Europe in 2020 Image
Ioannidis published a piece early 2021 in which he selects 40 sera studies which he considers as good

I just went through them and focused on those that concern western Europe

This covers DE, FR, IT, SP, PT, AT, IR and NO so quite a lot!

1/ Image
And the result is simple: All datapoints are with IFR >1%

(I am still trying to figure out a way to add more info on each data point / will be for an addendum later)

2/ Image
Read 10 tweets
Jul 26, 2025
The paper by Ioannidis & al concluding "C19 vax saved ~1-4m" got published

As I flagged at the time of release⤵️, the paper relies on assumptions which are (often massively) too pessimistic vs the few real data points

But also its conclusions are marred by an error of logic

1/
The conclusion on lives saved depends on the severity of Omicron vs. Delta and Wuhan

By chance, Omicron proved much less intrinsically severe than Delta ... but we couldn't know this in 2021

So the study's conclusions on the legitimacy of measures are based on hindsight

2/
The correct way to do this analysis would be to
- include the full range of assumptions incl. real life data, ie IFR 2-5x higher, efficacy 50%-80% higher, etc.
- make the legitimacy of actions based on the options for Omicron's potential severity AS VIEWED from mid 2021 data

3/
Read 8 tweets
Jul 25, 2025
Only the UK had a good idea of its infections and yet I am not aware of a single study using it to determine IFR of covid by age

A study was published today by Ioannidis et al on lives saved by vaccines and their IFR is massively lower than the real data based on from the UK

1/ Image
Ioannidis et al rightly split the 70+ into community and care settings

I applied both to the population of England and Wales assuming 400k care places and hence 800k people of the 70+ (average stay = 2 years) exposed to covid via care settings

2/ Image
So of course this will massively impact estimation of lives saved from vaccines (and impact multiple other analyses and post-mortems of the pandemic management)

And yet nobody really seems to care

It's really strange

END
Read 4 tweets
Apr 30, 2025
This study looks well done but I don't see how it allows for "concerns about vaccines" as conclusion line

To take an analogy, if a study found higher car mortality in men than women wearing a seat belt, you would not expect "concerns about seat belts" as conclusion line

1/
I asked the authors about it also because, actually all studies of age-adjusted mortality by vax status show a higher rate among the unvaxed

So, without further further info about unvaxed, the conclusion to date here is that Moderna reduced mortality even more than Pfizer

2/
I may be missing something here of course and I put my surprise on the conclusion line to the authors

But I like the study itself on the comparison between the two vaccines as the authors spent a lot of efforts, as it should, to avoid confounders between their two groups

END
Read 5 tweets
Apr 3, 2025
If you are in covid twitter, you will see this headline pass your tweet today

"Quasi consensus in the French Medical academy for a lab origin of covid" relayed by the normally very serious @Sciences_Avenir periodical on science

Only issue? It is not true... Image
@Sciences_Avenir What happened is that the academy
- got a presentation on a report of the covid origin, available here
- was asked to approve the conclusions of the report (see screenshot) which are on the measures to minimize lab risks NOT ON THE ORIGIN OF COVID ITSELF Image
The report goes through the usual points in favour of animal and lab origins of covid

Then, sensibly, the report concludes: "we will never know for sure for covid but we need to make sure to minimize any risk, including lab risk"

Unsurprisingly, 97% of the academy approves this
Read 5 tweets

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