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Clean Air Club Profile picture
@Clean_Air_Club_
Jul 30, 2023 • 9 tweets • 3 min read • Read on X
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👃🏽💦 Nasal sprays are an under-used but highly effective layer to include in your covid-safety strategy! 👃🏿 Here's a thread on 4 really effective ones: There are many nasal sprays available on the market that have been shown to reduce the transmission of covid as well as reduce the severity of covid illness if infected. Picture of 5 different nasal sprays, with blue smiley faces and the clean air club logo
No. 1: Carrageenan Nasal Spray - with an 80% relative risk reduction, this nasal spray is one of the best I've found. Carrageenan nasal spray: iota carageenan is an antiviral polysaccharide that binds to viruses and inhibits viral replication and propagation. 80% risk reduction, $20. Brands: Nasitrol, salinex, agovirax, betadine cold defense nasal spray.
No. 2: Hypromellose Spray - this one is a close second at 78% relative risk reduction. Also pretty affordable! Hypromellose nasal spray changes the ph of the nasal cavity with an acidic gel layer that is shown to reduce the risk of viral infection. 78% relative risk reduction, $20.
No. 3: Nitric Oxide Nasal Spray (NONS) - this one is widely-used with a 75% relative risk reduction. With the higher price, though, you're probably better off with Carrageenan or Hypromellose sprays! Nitric oxide nasal spray destroys viruses and impedes viral replication within the cells in the nose. It has also been shown to block the ACE-2 receptor essential for the covid virus to infect our cells. 75% risk reduction, $60. Brands include enovid, sanotize, virx.
No. 4: Xylitol - this spray is the most affordable, but it has a lower risk reduction than the others at 62%. Still *way* better than nothing though! Xylitol is a natural virucidal agent that alters the optimal acidic environment required for cell invasion, preventing viral entry into the nasal epithelium. 62% risk reduction, $12 each. Brand: Xlear.
How to use: each spray has slightly different instructions. In general, though, you spray before and after a potential covid exposure in order to reduce the chances of infection. You can also use it repeatedly throughout the day(s) after a potential exposure.
Some things to consider: take a look at the ingredients lists, studies, and safety profiles to make a decision for yourself about whether to incorporate this into a multi-layered covid strategy. These sprays are not just saline solution!
Some of these sprays are manufactured in Israel. There is conflicting information online, and apparent disagreement within the movement itself, regarding whether purchasing medical goods produced in Israel (and nowhere else) is in violation of the BDS boycott.
📖 Citations 📖

Carrageenan:

Hypromellose: https://t.co/f0G1wbNfFD

NONS: https://t.co/1OJkHABGAT

Xylitol: https://t.co/DBJV0wiX29ncbi.nlm.nih.gov/pmc/articles/P…
ncbi.nlm.nih.gov/pmc/articles/P…
respiratorytherapy.ca/pdf/RT-18-2-Sp…
ncbi.nlm.nih.gov/pmc/articles/P…

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More from @Clean_Air_Club_

Clean Air Club Profile picture
Jul 18
Nasal irrigation is one of the cheapest covid precautions you can add to your routine! 🧵 Nasal Irrigation for Covid-19: cheap, effective, and well-tolerated. An illustration of a woman doing a nasal rinse is in the center with the clean air club logo in the bottom right.
💧Nasal rinsing is the process of rinsing a saline solution through your nasal passages to clear out mucus, debris, and allergens. It also reduces the chances you'll become infected when exposed & reduces illness severity and duration if you're infected. (citations in 🧵)
There are great studies backing up nasal irrigation (rooted in the ancient practice of Jala Neti)

Here's one: ncbi.nlm.nih.gov/pmc/articles/P…
“Overall, patients with positive swab tests experienced substantial viral load reduction, became PCR-negative faster, and had milder symptoms than untreated patients. Hence, repeated application of [nasal saline irrigation] can be recommended for fastening viral clearance, symptom relief, and prophylaxis against respiratory infection, as has been increasingly proposed in (self-care) treatment or hygiene prevention guides for COVID-19.” Citation: Huijghebaert et al., “Saline nasal irrigation and gargling in COVID-19: a multidisciplinary review of effects on viral load, mucosal dynamics, and ...
Read 8 tweets
Clean Air Club Profile picture
Jun 30
🧪 Not all covid tests are made the same!!

Would you rely on a smoke detector that only beeped during 28% of fires?

If not, then don't rely on one regular rapid test that picks up on covid only 28% of the time. 🥴

Stats below!! A bar graph comparing the sensitivities of different tests. The title reads "Covid test sensitivity: If you have asymptomatic covid, these are the chances that each test will actually detect it and show a positive result." 1 rapid antigen test is at 28%; 2 rapid antigen tests 48 hours apart is 63%. Lucira covid and flu test is 89%. 3EO molecular test is 95%. Metrix is 97%. Pluslife is 98%. "Takeaway: negative results on regular rapid tests don't tell you much. Citations in caption."
Citations:

1. Zhu et al., “Trial of the Pluslife SARS-CoV-2 Nucleic Acid Rapid Test Kit: Prospective Cohort Study” JMIR Public Health Surveill. 2023; 9: e48107.

2.

3. “Aptitude Matrix COVID-19 Test: Instructions for Use For Healthcare Providers”virus.sucks/pluslife_en/
4. “3EO Health: COVID-19 Test Instructions for Use”

5. “Performance Evaluation of the Lucira COVID-19 + Flu Test” Note that PPA and NPA were used for the sensitivity and specificity stats above.
Read 6 tweets
Clean Air Club Profile picture
Jun 26
✈️ A guide to Covid-Safer Flying ✈️ a black and white vintage picture of an airplane in the sky. Text reads "Covid safer flying" and "update!" There is a clean air club logo in the bottom right.
Before the Airport: Gear

Please treat this as a recommendation of many layers to consider, and remember that any single layer is better than none. The most important layer here, masks, can be achieved for under $5!

Links to recommended gear will be at the very end of the thread Before the airport: If possible, invest in some gear that will help you navigate plane travel. We recommend N-95 masks, the Sip Valve (practice beforehand), glasses (prescription or not), a portable far-UVC lamp or portable purifier, a portable CO2 monitor, antiviral nasal spray, mouthwash with cetylpyridinium chloride (CPC), antiviral herbal tinctures, and a neti pot.
Before the Airport: Prep Try to hydrate extensively for the 48 hours before you plan to arrive at the airport. You may also consider drinking coconut water or water mixed with oral rehydration salts beforehand so that you retain water better. Test for Covid the morning of your flight, then eat a large meal. The goal is to reduce the need to take off your mask as much as possible.
Read 12 tweets
Clean Air Club Profile picture
May 30
🧪Not all covid tests are made the same!!

Some of them detect negatives *much* better than others. Check out the comparisons below, and try to use the highest accuracy testing you can afford. A chart titled “Covid test sensitivity: how confident you can be if your covid test is negative and you have no symptoms.” There are 6 bar graphs showing the performance of different covid tests. 1 Rapid antigen test: 28%. 2 rapid antigen tests 48 hours apart: 63%. Lucira covid and flu molecular test: 89%. 3EO molecular test: 95%. Metrix molecular test: 97%. Pluslife molecular test: 98%. Text below reads: “Reminder: if you get a positive result on any of these tests, it’s 99% accurate. Citations in caption.” Clean Air Club logo is in bottom right.
Citations:

1. Zhu et al., “Trial of the Pluslife SARS-CoV-2 Nucleic Acid Rapid Test Kit: Prospective Cohort Study” JMIR Public Health Surveill. 2023; 9: e48107.

2.

3. “Aptitude Matrix COVID-19 Test: Instructions for Use For Healthcare Providers”virus.sucks/pluslife_en/
4. “3EO Health: COVID-19 Test Instructions for Use”

5. “Performance Evaluation of the Lucira COVID-19 + Flu Test” . Note that PPA and NPA were used for the sensitivity and specificity stats above.web.archive.org/web/2023101721…
clinicaltrials.gov/study/NCT06141…
Read 5 tweets
Clean Air Club Profile picture
May 27
🧪Here's an updated roundup of highly reliable, easy-to-use molecular covid tests on the market today!

Accuracy stats, cost per test, and citations throughout. 🧵 At-Home Molecular Covid Testing: Regular rapid tests don’t produce reliable negative results. Luckily, there are at-home molecular tests that have an accuracy approaching what you get from PCR tests, the gold-standard in viral detection! Increase the reliability of your covid testing by using one of these fast at-home molecular tests. Pictured are four test readers, the clean air club cloud logo, and a sticker that says "update!"
🏆 Coming in at #1, we have the Pluslife Minidock!

This one has an amazing 98.3% test sensitivity -- meaning if it shows a negative result, you can rely pretty heavily on that.

Read more here:

Citation: virus.sucks/pluslife_en/
publichealth.jmir.org/2023/1/e48107
Pluslife Covid test: Reader cost: $310 (DM Clean air club for discount) Test cost: $8 Sold via Altruan.com DM Clean Air Club for discount code Test sensitivity: 98.3% (how reliable a negative result is) Test specificity: 99.3% (how reliable a positive result is) Pluslife also has tests for HPV, Strep, Mpox, Influenza A+B, RSV, and viruses that affect household pets Citation: Zhu et al., “Trial of the Pluslife SARS-CoV-2 Nucleic Acid Rapid Test Kit: Prospective Cohort Study” JMIR Public Health Surveill. 2023; 9: e48107. See also: https://virus.sucks/pluslife_en/
🥈 At a close 2nd place, the Metrix molecular test has an impressive 96.7% test sensitivity and a much cheaper startup cost (though this is negated over time by the more expensive tests). Also a really good system to get.

Citation: web.archive.org/web/2023051116…
Metrix Covid Test: Reader cost: $50 Test cost: $25 Test sensitivity: 96.7% Test specificity: 99% Cost goes down when you buy the reader and tests bundled Citation: “Aptitude Matrix COVID-19 Test: Instructions for Use For Healthcare Providers” https://web.archive.org/web/20230511163447/https://www.fda.gov/media/162403/download
Read 8 tweets
Clean Air Club Profile picture
Nov 26, 2023
Covid can damage every organ system in your body. Here is the labwork to seek out after the acute infection phase has passed. 🧵
The CDC recommends labwork organized by health concern.

1. Blood count, electrolytes, and renal function:
-CBC w/ possible iron studies
-Basic metabolic panel

2. Liver function:
-Liver function tests
-Complete metabolic panel

cdc.gov/coronavirus/20…
3. Inflammatory Markers
-C-reactive protein
-Erythrocyte sedimentation rate
-Ferritin

4. Thyroid Function
-TSH
-Free T4

5. Vitamin Deficiencies
-Vitamin D
-Vitamin B12
Read 8 tweets

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