Our latest STH article "Post COVID-19 Large Vessel Vasculopathy in a Previously Healthy Young Male"
🔬🧑🔬We discovered significant damage and scarring of arterial walls - less than 2 years after COVID-19 infection in a healthy, 35 year old male #LongCovid thieme-connect.com/products/ejour…
👉Our patient had post acute sequelae of COVID-19, suffering from recurrent thrombosis/acute ischaemic limb
👉Extensive fibrosis, accumulation of fibromyxoid material was found within the walls of a femoral arterial biopsy
👉This is likely from persistent endothelial dysfunction
👨🏻⚕️Evidence for this persistent endothelial dysfunction, inflammation, and hypercoagulability can be found in some Covid-19 survivors, as shown by our study in Singapore 🇸🇬 onlinelibrary.wiley.com/doi/10.1002/aj…
Work by our COVID-19 Clotting and Bleeding Investigators team found that platelet hyperactivation was seen in a group of our Covid-19 survivors who experienced a spectrum of illness, from asymptomatic Covid to the critically ill requiring ICU care thieme-connect.com/products/ejour…
Early in the pandemic (2020), we managed young patients who presented with delayed, catastrophic stroke and heart attacks - these patients had thrombotic events weeks to months after their initial COVID-19 infection 🏥 link.springer.com/article/10.100…
🚨Endothelial dysfunction remains the cornerstone in post-COVID-19-associated thrombosis, where chronic dysregulation of the endothelium can foster large vessel vasculopathy, even in previously healthy patients. thieme-connect.com/products/ejour…
• • •
Missing some Tweet in this thread? You can try to
force a refresh