Benjamin Ryan Profile picture
Sep 25, 2023 10 tweets 4 min read Read on X
In a bold new paper, three academics criticize how #longCovid has been studied. They say the term itself is so ill defined it should be discarded and that the studies have often been riddled with bias.
By: @VPrasadMDMPH @TracyBethHoeg @ShamezLadhani
🧵⬇️
ebm.bmj.com/lookup/doi/10.…
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#LongCovid prevalence, @VPrasadMDMPH @TracyBethHoeg @ShamezLadhani argue in @BMJ_EBM, has been over-estimated due to "overly broad definitions, lack of control groups, inappropriate control groups and other methodological flaws." This has caused "undue concern and anxiety." 2/ Image
The paper's authors define #longCovid as a syndrome or individual symptoms that are a direct effect of Covid lasting at least 12 weeks. But they advise others in their field to discard the term "and instead more narrowly define certain post-Covid syndromes or symptoms." 3/ Image
@VPrasadMDMPH, @TracyBethHoeg and @ShamezLadhani criticize four international health organizations, including the @CDCgov, @WHO and others, for not requiring a causal link between coronavirus infection and long Covid (aka post-acute sequelae of Covid-19, or PASC). 4/ Image
A review paper found that, of studies that looked at long Covid interventions, only 54% required that the members of the study have lab-confirmed Covid. One study found that self reporting LC was more strongly tied to a belief of having had Covid than a Covid diagnosis. 5/
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Long Covid, @VPrasadMDMPH, @TracyBethHoeg and @ShamezLadhani write, also suggests a permanent condition. However, there is good evidence that the associated symptoms do indeed improve over time. 6/ Image
@VPrasadMDMPH, @TracyBethHoeg and @ShamezLadhani criticize the lack of control groups in many #longCovid studies. 7/ Image
@VPrasadMDMPH, @TracyBethHoeg and @ShamezLadhani criticize many #longCovid studies for having what they characterize as inappropriately matched control groups. 8/ Image
@VPrasadMDMPH @TracyBethHoeg @ShamezLadhani suggest improvements to long Covid research:
Avoid: misclassification bias, selection bias, detection bias, confounding by underlying health, information bias, sampling bias and mischaracterization; and reduce diagnostic ambiguity. 10/ Image
This is one of the most stunning examples, if not the most egregious example, of someone with a doctorate exaggerating the threat of #longCovid and sowing fear and panic.

Ladies and gentlemen, I give you @fitterhappierAJ: Image

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More from @benryanwriter

May 10
One of the authors of a just published critique of Britain’s Cass Review on pediatric gender medicine and the systematic reviews on which it was partially based suggests that the authors were “bribed.”

It’s unclear what McLamore means by the comparison of how long peer review took for them, since the Cass Review took four years and was not peer reviewed. But the SRs on which it was based were peer reviewed and published in a journal.

Quinnehtukqut McLamore (they/them) is an assistant professor of social psychology in the Department of Psychological Sciences at the University of Missouri at Columbia.Image
“The Cass report’s recommendations, given its methodological flaws and misrepresentation of evidence, warrant critical scrutiny to ensure ethical and effective support for gender-diverse youth.”

bmcmedresmethodol.biomedcentral.com/articles/10.11…
The lead author says: Image
Read 4 tweets
May 9
Today, I was on a Zoom call by an HIV advocacy group about their efforts to combat the Trump admin's cancellation of HIV research grants. One of the activists presenters said he refused to present if I was on the call, clearly due to my reporting on pediatric gender medicine.

The organizer said he couldn't eject anyone from the call; there were about 80 participants. (This despite the fact that that organizer, a longtime activist, had already ejected me from his HIV-advocacy listserv.) So the activist refused to present and had his colleague present in his place. She made a big point about how he had made an "ethical" stand not to present.

I told everyone via the chat on the Zoom that I stood by my reporting on pediatric gender medicine. Which I do.

The irony is that I am among only a small handful of reporters who maintains a specialty in HIV coverage—I have been writing about HIV for 25 years and started doing work in the field in 1995—and who writes for mainstream outlets. And I just published a major article in NBC News about the cancelation of LGBTQ-related research grants, the very subject of the Zoom call, that was totally sympathetic to the activists' cause.

I see a lot of this in my work, in which HIV activists seek to punish me for my reporting by seeking to stonewall and blacklist me. They go to great lengths. It winds up just being inconvenient for me; I still get my work done. What it does accomplish is it ensures that these activists' voices are not heard in my reporting. And it does not stop me from writing about gender medicine. It boils down to ideological purity on their part. They need to take that stand.
If these activists had their way, I would not publish articles like this that are very critical of the Trump administration and bring attention to the activists’ cause. Some of them tried to get my sources for this piece to join the blacklist against me. nbcnews.com/nbc-out/out-ne…
One of the sources for the piece above is a major academic advocate in the transgender space. I’ve interviewed him many times over the years. To his credit, he dismissed the demands from activists to blacklist me and said he’d just ask me himself what the story was with my gender medicine reporting. Imagine that!
Read 9 tweets
May 1
This is an apparent contradiction that adults such as myself have trouble reconciling with: that there is an apparent element of adolescent culture today that, at least in certain communities, values and valorizes trans over gay identities.

Erin Reed is thus incredulous at the suggestion in the new HHS report on pediatric gender-transition treatment:Image
Fact check: There are, in fact, two studies that have found that suicide deaths in gender distressed youths are rare:

link.springer.com/article/10.100…

mentalhealth.bmj.com/content/27/1/e… Image
The purpose of controlling for specialist psych visits was to determine if having gone to a gender clinic was *independently* associated with suicide death. It was not. Image
Read 5 tweets
May 1
NEWS: HHS has published a 409-page document, per Trump's request

Treatment for Pediatric Gender Dysphoria

Review of Evidence and Best PracticesImage
I haven't read this massive tome. But there is a reference to me in it. The footnote in this bit refers in part to a piece Jesse Singal wrote about the time Alejandra Caraballo and Steven Thrasher really came for me. Image
Read 5 tweets
Mar 24
100s of NIH research grants have been summarily canceled over the past couple of weeks, on the grounds that they support DEI, trans issues, or are at Columbia. Now Trump is targeting mRNA studies, which scientists tell me could jeopardize research into new cancer treatments, for one, as well as the quest for and HIV vaccine. Many of these grants have nothing to do with DEI per se or are particularly focused on transgender people in particular. They seem to have been flagged simply because they have key words that have drawn the attention, and ire, of DOGE. I only have second-hand reports of what DOGE has been doing inside of the NIH and the NIAID.
Today, a titan of biomedical research called me and was reduced to pleading over and over, “Why are they doing this?” as he watched in fear that his life’s work would be destroyed by the Trump administration.
I spoke with one prominent epidemiologist who said that their skills would not be of use outside of academia and that they’d discussed having to move to some cheap place in the country to be able to survive financially.
Read 5 tweets
Mar 12
LEAKED: Trans-Care Training Videos By Beleaguered Top Gender-Clinic Doctor, Part 1

I have obtained 12 hours of videos of top pediatric-gender-clinic physician Dr. Johanna Olson-Kennedy and her colleagues, including her husband, providing training to mental-health providers on how to treat minors who have gender dysphoria or otherwise identify as transgender or nonbinary.

This is the first of 12 installments I will post during the coming weeks of these videos. Subscribe to my newsletter (link in bio) to receive all of them as I publish them.

A 19-year veteran of the pediatric gender medicine field and one of its leading physician-researchers and advocates, Dr. Olson-Kennedy is the medical director of the gender clinic at Children’s Hospital Los Angeles. According to figures she provided during this particular video, annual referrals to her clinic surged from just 25 in 2010 to 436 in 2022—following a similar pattern seen in clinics throughout the Western world.

The past six months have been challenging for Dr. Olson-Kennedy, to say the least.

Dr. Olson-Kennedy is the principal investigator on a National Institutes of Health grant for a long-running research project concerning pediatric gender-transition treatment, one that has received over $10 million to date. In October, The New York Times reported that she has withheld null findings from a study of puberty blockers funded by this grant, doing so for political reasons. The grant is now the subject of a probe by congressional Republicans. In November, however, she asserted in a sworn deposition in a civil case that the Times had mischaracterized her words.

In December, Dr. Olson-Kennedy was sued by a former patient, Clementine Breen, who reported that the gender doctor prescribed her puberty blockers at age 12—on her first appointment, without a psychological assessment—and testosterone at age 13, and then referred her to receive a double mastectomy at age 14. Ms. Breen, now 20, has since detransitioned, reverting to presenting and identifying as a woman.

The Trump administration has unleashed an onslaught against the field of pediatric gender medicine, seeking to wipe it off the map. In recent weeks, the NIH has been canceling research grants related to transgender people, including those conducted with animal models. There is currently a preliminary injunction in place to block the president’s executive order that would freeze federal funds to hospitals that provide gender-transition interventions to those under age 19. Prior to the injunction, Dr. Olson-Kennedy’s clinic had “paused” new cross-sex hormone treatments for youth, only to lift the pause a couple of weeks later.

It remains unclear whether the grant for which Dr. Olson-Kennedy is the top investigator has been canceled. But it is no longer listed on the NIH site where active grants are described.

I reached out to Dr. Olson-Kennedy and her co-principal investigators on the grant to ask about its status. I did not hear back.

Prior to the October Times article, Dr. Olson-Kennedy was perhaps best known by the general public for a previous leaked video in which she was giving a training in 2018 to mental health care providers on how to write referral letters for minors seeking gender-transition surgeries. In the video, she expresses exasperation with what she sees as hand wringing over whether natal girls will later regret having their breast removed during adolescence. (At least 1,000 such surgeries have been conducted annually in recent years.)

She says: “What we do know is that adolescents actually have the capacity to make a reasonable, logical decision. And here’s the other thing about chest surgery. If you want breasts at a later point in your life, you can go and get them!”

Ms. Breen recently reported that she was undergoing reconstructive surgery to provide herself with new breasts. However, it is very unlikely she will ever be able to breastfeed should she have children.

Dr. Olson-Kennedy is also newly the president of USPATH, the U.S. branch of the medical-activist group the World Professional Association for Transgender Health. WPATH, which despite is name is largely a U.S.-based organization, has been besieged by damaging publicity over the past year, in particular after internal documents subpoenaed by Alabama’s attorney general revealed that its leadership was aware that the evidence behind pediatric gender medicine was weak and sought to paper over this fact.

12 hours of leaked Olson-Kennedy training videos

The 12-hour training in what is known as the gender-affirming care method for minors who identify as trans or nonbinary took place in late April 2024—a few weeks after Britain published the Cass Review, which found that this medical field is based on “remarkably weak evidence.” The training was led by Dr. Olson-Kennedy; her husband, Aydin Olson-Kennedy, who has a doctorate in social work and is a transgender man; and licensed clinical social worker Darlene Tando.

I obtained the videos a few months ago.

The training videos are a window into not just the methods of these individuals, but their overall attitudes about gender dysphoria and transgender and nonbinary identification in children. A prevailing attitude they share is one of indignation and irritation with a medical system that demands that children betray a substantial level of distress before they are granted gender-transition medications. Overall, these three favor less gatekeeping and less pathologizing of the mental states and internal lives of the children in their care. If a gender-incongruent child arrives in their care absent any particular distress about their identification as the opposite sex, they believe that that child should be granted the opportunity to medically transition by taking puberty blockers and cross-sex hormones if the family wishes.

I have edited the videos to snip or crop out images that would identify the participants in the training, whether because of Zoom-chat questions that pop up in the right-hand corner of the screen, or moments when a matrix of the participants is visible. You can watch the video at the beginning of this Substack. Otherwise, I wrote a summary below:
LINK:
LEAKED: Trans-Care Training Videos By Beleaguered Top Gender-Clinic Doctor, Part 1
benryan.substack.com/p/leaked-trans…
I am publishing 12 hours of videos of Dr. Johanna Olson-Kennedy and colleagues in which they train mental-health providers on treating children who have gender dysphoria or otherwise identify as trans.

Subscribe to my newsletter to receive all the videos as I publish them.Image
Video number 1: Johanna Olson-Kennedy on the gender basics
benryan.substack.com/p/leaked-trans…
Dr. Olson-Kennedy opens the video by charting the recent shift in transgender visibility in popular media, which she says has improved dramatically in recent years. Previously, transgender people were frequently presented as sex workers, according to at GLAAD analysis. But these days, TV has benefited from the likes of Jazz Jennings and shows like Transparent and Pose that center on the transgender experience, Dr. Olson-Kennedy says. Having stories about youth in the media in particular, she says, has influenced the seeking of gender-transition treatment by young people.

She expresses concern that the trans kids whose stories have been told in the media are generally white. This is reflective, she says, of the disproportionately white patient population at gender clinics in the U.S. and Europe. “It is important for all of us to think about what those barriers to care are for other communities and work really hard to dismantle those barriers.”

This remark speaks to a common dichotomy among advocates in this medical field: They will at once characterize the number of children receiving these treatments as low (as Dr. Olson-Kennedy does a bit later in the video), emphasizing that the political firestorm over this population is disproportionate to its size, while also decrying how few kids are receiving the treatment.

Since 2021, Dr. Olson-Kennedy says, we’ve seen a “problematic” visibility of trans youth as states have moved to ban these treatments. She shows a Google search she conducted of “transgender youth care” the night before. “All of these six headlines, and there’s many more,” she says, “are negative, and they speak to moves being made to ban access to care.”Image
Read 20 tweets

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