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Conor Browne Profile picture
@brownecfm
Nov 7 • 3 tweets • 1 min read Twitter logo Read on Twitter
1. There are several studies that show the potential for SARS-CoV-2 infection to activate latent TB. At the very least, this should be taken into consideration when attempting to determine why TB rates have risen to record levels.
2. This is the earliest study I could find:

sciencedirect.com/science/articl…
3. The hypothesised mechanism of latent TB reactivation in the above study is CD4+ T-cell depletion caused by Covid-19 disease.

@fitterhappierAJ

/end

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More from @brownecfm

Conor Browne Profile picture
Nov 9
1. I had a large electrical appliance delivered and installed at my home today. When the delivery van pulled up, I was waiting at my front door, wearing a respirator, as always. One of the two guys shouted over to me, 'you don't have Covid, do you'?
2. He was serious. This wasn't any kind of mask-shaming. I shouted across to him, 'no, I'm making sure I don't get it'. I stepped into my garage - door open - to let the two guys in to install the item.
3. The concerned guy said, passing me, 'I had it two years ago, I don't want it again, it was rough'. I replied, 'you should wear one of these', pointing at my Aura. A kind of muttered negative response in return.
Read 4 tweets
Conor Browne Profile picture
Nov 2
1. This is the paper that's making the headlines today. I've read it in full, and its findings are, in my opinion, robust, and, frankly, align with common sense. The problem is not the paper, but its misinterpretation by the media.

thelancet.com/journals/lanhl…
2. This problem is compounded by individuals commenting on the press release, rather than the paper itself, a common problem on this platform.

To be clear: this paper is emphatically not discounting the deleterious effects on cognition that often occur as a result of Covid.
3. As an example, a direct quote from the paper:

"The worsening of cognition in people with a history of COVID-19 aligns with literature reports of the cognitive effects of the disease, in which up to 78% of people report cognitive impairment".
Read 9 tweets
Conor Browne Profile picture
Oct 31
1. This is an excellent article. Trust is key to pandemic response. Trust between countries, trust in government, trust in public health, and trust between individuals. In an interview I gave in 2020, I made the point that the pandemic could not have arrived at a worse time.
2. With many countries - including, but not limited to - the US and the UK, already in the grips of significant political polarisation, it was obvious to me that pandemic response would become very politicised, very quickly. And, of course, it did.
3. And this intense politicisation - primed by a complete (and often justified) mistrust of the government before the pandemic began - set the scene for individuals (again, justifiably) not trusting the government's pandemic response.
Read 9 tweets
Conor Browne Profile picture
Oct 31
1. A fantastic Halloween article from @BulletinAtomic , well worth a read. One line stands out:
2. 'In his novel, World War Z: An Oral History of the Zombie War, Max Brooks says “Most people don’t believe something can happen until it already has. That’s not stupidity or weakness, that’s human nature" '.
3. I would only add that, in the case of the Covid-19 pandemic, this effect is even worse, because most people now believe it's over, rather than understanding that it's still happening. To continue the analogy in the article:
Read 4 tweets
Conor Browne Profile picture
Oct 26
1. This is a very important point in a superb thread from Dr. Duncan. In my own experience, most members of the general public have an understanding of Covid-19 as follows: 'if I get Covid, I'll be sick for a few days. I might get Long Covid, but that's very rare'.
2. What I always explain is that this popular conception of Covid-19 is flawed in two crucial ways. First, that Long Covid is nowhere near as rare as most people think.
3. Second, that even if someone recovers fully from acute Covid-19 illness, as most people do, their risk of developing other health issues - cardiovascular, autoimmune etc - is significantly elevated by SARS-CoV-2 infection.
Read 4 tweets
Conor Browne Profile picture
Oct 23
1. Remember: when Covid community transmission is high, hospitals will always have an increase in patients admitted with Covid. This then leads to increased levels of nosocomial infections, which leads to increased morbidity and mortality for patients not admitted for Covid.
2. In short, hospitals are placed under intense, and cascading strain - the latter because healthcare settings are *always* hotbeds of infections during disease outbreaks, which means not only do patients enter the hospital with Covid, but visitors may well leave with it.
3. These infected visitors (and staff) then seed further clusters of infection in the community, and the cycle continues. Since no non-pharmaceutical interventions are in place in the community, and since this will keep happening until we have better vaccines, the solution is:
Read 4 tweets

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