"Can't Think, Can’t Remember: More Americans Say They’re in a Cognitive Fog"
"Adults in their 20s, 30s and 40s are driving the trend. Researchers point to #LongCovid as a major cause." nytimes.com/2023/11/13/ups…
“Richard Deitz, an economist at the Federal Reserve Bank of New York, analyzed the data and attributed much of the increase to #LongCovid”
“These numbers don’t do this — they don’t just start suddenly increasing sharply like this,” he said.
@LongCovidSOS @patientled @PandemicPatient @long_covid @MarkedByCovid @LongCOVIDPhysio @PeoplesCDC @LongCovidKids @C19LH_Advocacy @polybioRF “There are more Americans who say they have serious cognitive problems — with remembering, concentrating or making decisions — than at any time in the last 15 years, data from the Census Bureau shows.
“The increase started with the pandemic” #LongCovid
"The number of working-age adults reporting 'serious difficulty' — thinking has climbed by an estimated one million people... And younger adults are driving the trend." #LongCovid
"The sharp increase captures the effects of #LongCovid for a.. significant portion of younger adults, researchers say"
"The rise in cognitive issues aligns with a common symptom that plagues #LongCovid: 'brain fog'
"Emmanuel Aguirre, a 30-year-old software engineer in Bay Area, had Covid in 2020. Within a month, he said, his life was transformed"
“I felt like I was permanently hung over, drunk, high & in a brain freeze all at once.”
"He stopped dating, playing video games & reading, though he managed to keep his job, working remotely..the brain fog has lingered, disappearing at times only to steamroll him days later."
"Cognitive impairment is a 'hallmark of #LongCovid,' said @zalaly"
“It’s not just fog, it’s a brain injury, basically,” said Dr. @MVGutierrezMD. "There are neurovascular changes. There’s inflammation. There are changes on M.R.I.s.” #LongCovid
"Studies estimate some 20-30% of people who get Covid have some cognitive impairment several months later, including people with symptoms ranging from mild to debilitating. Research has also shown clear biological changes from the virus related to cognition" #LongCovid
"Heather Carr, 31, sold agricultural machine parts in Syracuse, N.Y., but two coronavirus infections left her largely bed-bound & barely able to string together a basic train of thought. She had trouble staying awake while driving, & eventually had to give up her job." #Longcovid
“I cry when I try to think, now,” she said. “My brain short-circuits.”
..the number of working-age Americans with a disability who are employed has increased by an estimated 1.5 million people, census data show." #LongCovid
“We need to take this very seriously as a society. We need to understand who these people are, how they’re being impacted and what we can do about it.” — Monika Mitra, who directs the Lurie Institute for Disability Policy at Brandeis University. #LongCovid
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“People infected multiple times with COVID-19 are more likely to develop #LongCovid, and most never fully recover from the condition. Those are two of the most striking findings of a comprehensive new 3-year research study” medscape.com/viewarticle/99…
“Most people do not really fully recover.
There are people who think, ‘This is a nothing-burger anymore,’ or ‘It's not an issue anymore.’ — #LongCovid is still happening with the current variants.”
“#LongCovid is not uncommon. We see it in the clinic in large numbers.”
“Not all long COVID is the same, and that's really what makes it complex and makes it really hard to deal with in the clinic. But that's the reality that we're all dealing with.”
"Everyone who's engaged in #LongCovid research should now be thinking about this.. pathway," — @VirusesImmunity
"I'm impressed by the study," says Dr. Monje, @Stanford. "I think they did a beautiful job showing the causality of these changes." npr.org/sections/goats…
“The study weaves together several prominent lines of evidence on the potential drivers of #LongCovid — the ongoing presence of viral material, blood clotting and chronic inflammation — and offers up possible targets for clinical trials that can test treatments in humans.”
"Basically, we can explain some of the neurocognitive manifestations of #LongCovid through this pathway that leads to serotonin reduction," says Christoph Thaiss, a senior author on the study and an assistant professor of microbiology at the @Penn
“Historically, @US_FDA has required 2 ‘adequate’ trials before it approves a drug. In Amylyx’s case, a subsequent trial was likely to take 3 more years. The A.L.S. community felt that there was no time to waste. The majority of current patients would be dead if they had to wait”
"ALS was first described a 150 years ago, but we still have a lot to learn.. @gregggonsalves father recently died after a long descent into dementia."
“We need better drugs for neurodegenerative diseases..But the way to do it is not to say, ‘Open the floodgates of the F.D.A.’ ”
“In their study researchers at @Penn suggest serotonin reduction is triggered by remnants of the virus lingering in the gut.”
“This is one of several new studies documenting distinct biological changes in the bodies of people with #LongCovid” — @nytimes nytimes.com/2023/10/16/hea…
“The authors said the biological pathway that their research outlines could unite many of the major theories of what causes #LongCovid: lingering remnants of the virus, inflammation, increased blood clotting and dysfunction of the autonomic nervous system.”
@LongCovidSOS @long_covid @MarkedByCovid @LongCovidKids @LongCOVIDPhysio @PandemicPatient @patientled @LongCovidFam @C19LH_Advocacy “This is an excellent study that identifies lower levels of circulating serotonin as a mechanism for long Covid,” said @VirusesImmunity, an immunologist at @Yale.
“Her team identified other biological changes linked to of #LongCovid”.
"Clinical observations and a large study published in March support that theory. Among the 282,000 people in the study who were eligible for Paxlovid, the drug was associated with a 26% lower risk of #LongCovid."
“Research definitely backs up that it helps prevent lingering symptoms — it helps prevent #LongCovid,” said Ashley Drapeau, director of the Long Covid Clinic at the GW Center for Integrative Medicine.
“We’re not saying that thrombotic endotheliitis is the beginning and the end, but we are saying it is a prominent and specific part of the reason why we see #LongCovid symptoms,” says @resiapretorius cen.acs.org/biological-che…
"One of the biggest misperceptions is that vaccination or prior infection protects you, or that you’ll react the same to every COVID infection." — @ahandvanish, co-founder of @patientled #LongCovid cen.acs.org/biological-che…
@ahandvanish @patientled “@resiapretorius was part of a team that inspected #microclots for their composition. Inflammation from SARS-CoV-2’s spike proteins commonly results in endothelial damage, which leads to pathologic clotting. Clotting in turn can perpetuate further inflammation & vessel damage.”