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Dr. Lisa Iannattone Profile picture
@lisa_iannattone
Nov 17 • 9 tweets • 3 min read Twitter logo Read on Twitter
“We report a consistent increase in the risk of persistent symptoms after reinfection compared to first infection. All post-acute symptoms mentioned in the WHO clinical case definition appeared more common after reinfection than after a 1st infection”

‘RoBuSt HyBriD iMmuNiTy’ 🤪 Screenshot of the article linked in the next tweet “The burden of post-acute COVID-19 symptoms in a multinational network cohort analysis”
Yet another study showing that more infections = more morbidity. Can we like warn people maybe? Feels like something people might want to know.
nature.com/articles/s4146…
“Escalation of commitment: A human behavior pattern in which an individual or group facing increasingly negative outcomes from a decision, action, or investment nevertheless continue the behavior instead of altering course.”

¯\_(ツ)_/¯
Oops.

“Our results show that the first episode of SARS-CoV-2 infection induces a significant increase in neutralizing titers in triple vaccinated individuals and that previous SARS-CoV-2 infection compromise significantly the neutralization response induced by reinfection”
Oops again.

“We found that those who had battled the BA.1-2 variant of Omicron in early 2022 had a 30-fold higher risk of contracting the BA.5 variant later in the year. That was exactly the opposite of what we, or anyone, would have predicted.”
So much oops.

“Our findings suggest that COVID-19 contributed to the 2022 surge of RSV cases in young children through the large buildup of COVID-19-infected children and the potential long-term adverse effects of COVID-19 on the immune and respiratory systems.”
Throwback oops.

“The evidence shows that reinfection further increases risks of death, hosp and sequelae in multiple organ systems in the acute and postacute phase. Reducing overall burden of death and disease due to SARS2 will require strategies for reinfection prevention.”
“[Scientific] uncertainty is manufactured to create the latitude for implementing disease control policies that run counter to broad societal values.”
Bonus oops.

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More from @lisa_iannattone

Dr. Lisa Iannattone Profile picture
Nov 14
I’m very optimistic that vaccine/treatment breakthroughs + better air hygiene standards will change the game at some point. But I’d also like to point out that preserving one’s short and long term health is an endgame in and of itself. It’s the endgame for so many things we do…
The endgame of exercise? Health.
The endgame of limiting alcohol? Health.
The endgame of treated tap water? Health.
The endgame of tossing spoiled food? Health.
The endgame of cooking meat to temp? Health.
The endgame of washing your hands? Health.
The endgame of screening and checkups? Health.
The endgame of carseats and seatbelts? Health.
The endgame of helmets? Health.
The endgame of brushing your teeth? Health.
The endgame of condoms? Health.
The endgame of indoor smoking bans? Health.
Read 7 tweets
Dr. Lisa Iannattone Profile picture
Nov 4
If I said you had a 1 in 10 chance of winning the lottery each time you play, do you like those odds? How many times would you play?

If I said you have a 10% chance of winning chronic health issues each time you catch covid, do you like those odds? How many times would you play?
Covid isn’t a one a done disease. Every time you catch the virus, you’re risking your health again. The spectrum of post acute sequelae is wide and includes heart problems, strokes, autoimmune diseases, immune system dysfunction, viral brain injury, POTS… the list is long.
Disability rates haven’t stabilized since the great mass infection event of early 2022. They’re still rising. These are the rates for the US and the UK.

How many times do PH leaders plan to have everyone mindlessly play the chronic disease/ disability lottery? What’s the plan?
US bureau of labor statistics graph of civilian labor force 16+ with disability showing a continuous rise since 2020 that hasn’t leveled off.
UK ONS labour market survey graph of number out of the workforce due to long term sickness showing a continuous rise since 2020 that hasn’t leveled off.
Read 10 tweets
Dr. Lisa Iannattone Profile picture
Jul 23
Covid infections can cause strokes, heart attacks and pulmonary embolisms in the post-acute phase. Even if the acute infection is mild. Even if you’re vaccinated/boosted. Even if you’re healthy. Even if you’re young. Even if you already caught it before and have “hybrid immunity”
“Prior to the COVID-19 pandemic, heart attacks were the leading cause of death worldwide but were steadily on the decline. However, the new study shows that heart attack death rates took a sharp turn and increased for all age groups during the pandemic.”

cedars-sinai.org/newsroom/covid…
Even if you’re young…

“Furthermore, the data showed the increase was most significant among individuals ages 25-44, who are not usually considered at high risk for heart attack.”
Read 7 tweets
Dr. Lisa Iannattone Profile picture
Jul 21
So how does this whole “you only need to wear a mask with immunocompromised patients” guideline work in practice? You walk into the room masked and after taking the patient’s medical history if they aren’t IC, you take it off? The absurdity somehow continues to reach new heights.
Or is it the even more absurd inverse scenario where you walk in unmasked and if after taking the patient’s medical history, they turn out to be immunocompromised, you put your mask on? It would be too little too late at that point. You’ve already exposed them to your aerosols.
Unmasking in healthcare is 100% about the “comfort” of healthcare workers and 0% about the safety of patients and I’m not here for it. We should strive to adhere to a much higher ethical standard than this in healthcare.
Read 7 tweets
Dr. Lisa Iannattone Profile picture
Jul 20
If your institution is hosting an event on equity, diversity and inclusion without having given a single thought to covid safety, effectively rendering your EDI event inaccessible to the disabled and medically vulnerable, I have some bad news for you…
How the absurdity of this scenario doesn’t seem to dawn on people spontaneously is astounding. Truly.
Someone suggested that I need to spell this one out clearly so here I go:

‘Equity, diversity, and inclusion’ initiatives are meant to make the institution more accessible to protected and underrepresented classes of people, to make the institution more equitable and diverse.
Read 11 tweets
Dr. Lisa Iannattone Profile picture
Jul 1
Yes the smoke smells like plastic. And the reason is horrifying:

“The VOC’s from the wildfire smoke interact with UV radiation to create benzene and formaldehyde compounds in the atmosphere. These are toxic air pollutants – and they happen to smell like burning plastic.”
But don’t worry, the deciders decided that the general public doesn’t need to wear N95s to protect us from the cancer air on particularly bad cancer-air days. Phewwww. I feel so much safer now, don’t you? /s
Wow. Someone pointed out that these are gases/vapours. N95s help with smoke but not VOCs. You need an even higher grade respirator to protect you from these compounds. Half-mask or full-face respirators with organic vapor cartridges.

I hate this timeline.
Read 7 tweets

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