拍帮主 (PBZ) Profile picture
Jan 21, 2024 7 tweets 3 min read Read on X
Looks like folks here are not familiar with it?

Let me try to explain in layman language then.

The cloth is called "free-fit lip" by Koken, or "face seal" by other manufacturers, but they are basically the same.

They are air-proof. 1/n
The first benefit.

Let's say you are wearing a 3M aura. It fits quite well. Everything is good.

But you might notice it's a bit less breathable than its test result indicates. Why?

You can paint your face in red color and don your aura. It'll look like this. 2/n
Image
Image
You'll need the part in red to fit, therefore you could no longer use them to filter.

The total area of filtration material is reduced when you put on your aura.

And Aura is even not the worst case. Look at this! 3/n Image
With face seals you'll barely lose any filtration area because your face just don't touch the filter. It'll thus significantly improve breathability.

Even better, now you also have more area to fit your face, which improves fit factor as well. 4/n Image
As you may notice, most face seals come together with plastic frames.

Those frames are pre-shaped. They'll help make sure the face seals are pressed onto your face with as little leak as possible.

They also stretch the filtration material so as to maximize breathability. 5/n Image
I guess it's Shigematsu that first invented the face seal + frame combination. It has become quite popular in East Asia now.

With a proper frame and face seal, you can achieve 200+ fit factor even in ear loops. Image
And the best part is breathability.

It could be as low as 40PA (well this one is still in development). Image

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More from @paibangzhu

Apr 23, 2024
A new study from China led by Dr. Cao Bin et al confirms what Dr. Peluso et al found earlier, as well as what the NIH director mentioned during her interview, about viral persistence.

doi.org/10.1016/S1473-…
Dr. Faust interviewing the NIH director:
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Apr 7, 2024
Very interesting data from Denmark:

Their recent whooping cough outbreak was not caused by declined vaccination. 1/6 Image
It's also unlikely to be an artefact of increased testing. 2/6 Image
It's not caused by incidence of the most vulnerable age group: the newborns.

The <1 age group actually has both lower incidence and lower hospitalization risk than in the previous 2 outbreaks in 2016 and 2019! 3/6 Image
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Jan 28, 2024
Was on a business trip, brought with me (as usual) a hand luggage full of gadgets.

Guess what's in this white canvas bag?

1/n Image
A CR box🥳 2/n Image
Fairly easy to set up 3/n
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Read 7 tweets
Jan 7, 2024
Here's a recent video from Dr. Yunlong Cao.


TLDR:
- SA55 (nasal spray version) has ~80% effectiveness against symptomatic Omicron infection, with a price tag of ~$7 a week.
- Good safety profile as shown by 200K users.
- Now in phase-3 trial.
1/n bilibili.com/video/BV1294y1…
Image
- SA55 (injectable mAB version) provides long protection (~180 days) for those immunocompromised unvaccinated participants.
- Already used as treatment for ~2000 immunocompromised elderly in December 2022 in Beijing against BF.7.14, and was very effective.
- Also in phase-3.
2/n Image
- They're also collaborating with Moderna and other vax companies to develop new vaccines based on DMS predictions.
- In a retrospective analysis they're able to make WT vaccine by Apr 2020, or BA.5 vaccine by Sept 2022, using the DMS prediction approach.
3/n Image
Read 7 tweets

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