1/
Let’s learn some things today that the healthcare system doesn’t tell you and doesn’t want you to know: (thread)
Cholesterol→ produced in the liver from “acetyl CoA”, a derivative and intermediary from fat and carbohydrate metabolism, and is the precursor of many other steroid hormones, such as:
1. estrogen
2. testosterone
3. pregnenolone
4. DHEA
5. progesterone
6. vitamin D
7. cortisol.
It is plays a vital role in the structure and function of the cellular membrane (protection), and is also an antioxidant, particularly to lipid-soluble free radicals, toxins, and other oxidative compounds.
Let’s learn some things today that the healthcare system doesn’t tell you and doesn’t want you to know: (thread)
Cholesterol→ produced in the liver from “acetyl CoA”, a derivative and intermediary from fat and carbohydrate metabolism, and is the precursor of many other steroid hormones, such as:
1. estrogen
2. testosterone
3. pregnenolone
4. DHEA
5. progesterone
6. vitamin D
7. cortisol.
It is plays a vital role in the structure and function of the cellular membrane (protection), and is also an antioxidant, particularly to lipid-soluble free radicals, toxins, and other oxidative compounds.
2/
Made from cholesterol:
▪Aldosterone is made from cholesterol, acts on the kidneys to help balance electrolytes and water to regulate blood volume and blood pressure.
Made from cholesterol:
▪Aldosterone is made from cholesterol, acts on the kidneys to help balance electrolytes and water to regulate blood volume and blood pressure.
3/ ◦Glucocorticoids→made from cholesterol, it’s produced in the adrenal glands and helps turn off inflammation, turn on anti-inflammation, development and homeostasis of T cells (immune cells), transport proteins not in the liver, stimulates fat metabolism, and preserves glucose uptake (fasting/high cortisol).
4/
Sex Hormones:
▪Progestogens→made from cholesterol, they help create:
▪Pregnenolone →made from cholesterol, it:
1. enhances nerve myelination (growth and healing) and serves as a neuroprotectant
2. it controls formation and stabilization of the structure of nerves
3. affects neural development during prenatal development, as well as
4. affects neural growth and reorganization during aging.
Sex Hormones:
▪Progestogens→made from cholesterol, they help create:
▪Pregnenolone →made from cholesterol, it:
1. enhances nerve myelination (growth and healing) and serves as a neuroprotectant
2. it controls formation and stabilization of the structure of nerves
3. affects neural development during prenatal development, as well as
4. affects neural growth and reorganization during aging.
5/
▪Progesterone →made from cholesterol, it contributes:
1. embryo development
2. pregnancy
3. the menstrual cycle
4. breast development
5. increasing the collagen content of connective tissue.
6. has a role in skin elasticity and bone strength, reduces spasm and relaxes smooth muscle.
7. Expands the airways and acts as an anti-inflammatory agent
8. regulates the immune response
9. improves glucose homeostasis and increases beta-cell proliferation (insulin secreting cells of the pancreas).
It’s also a neurosteroid, and can be metabolized within all parts of the central nervous system:
1. enhances the function of serotonin
2. has a protective effect on damaged brain tissue
3. contributes to nerve tissue healing and myelination
▪Progesterone →made from cholesterol, it contributes:
1. embryo development
2. pregnancy
3. the menstrual cycle
4. breast development
5. increasing the collagen content of connective tissue.
6. has a role in skin elasticity and bone strength, reduces spasm and relaxes smooth muscle.
7. Expands the airways and acts as an anti-inflammatory agent
8. regulates the immune response
9. improves glucose homeostasis and increases beta-cell proliferation (insulin secreting cells of the pancreas).
It’s also a neurosteroid, and can be metabolized within all parts of the central nervous system:
1. enhances the function of serotonin
2. has a protective effect on damaged brain tissue
3. contributes to nerve tissue healing and myelination
6/
▪Allopregnanolone→made from cholesterol, it has strong anti-depressant, anti-anxiety, stress-reducing, rewarding, pro-social, anti-aggressive, increased libido, sedative, pro-sleep, cognitive, anti-pain, anti-convulsant, neuro-protective, and potent neuro-regenerative effects.
▪Allopregnanolone→made from cholesterol, it has strong anti-depressant, anti-anxiety, stress-reducing, rewarding, pro-social, anti-aggressive, increased libido, sedative, pro-sleep, cognitive, anti-pain, anti-convulsant, neuro-protective, and potent neuro-regenerative effects.
7/
▪Androgens→made from cholesterol in the gonads (testes and ovaries) and also in the adrenal glands. The testes produce a significantly higher quantity than the ovaries. They help:
1. create testosterone
2. build skeletal muscle
3. drive libido
4. mediate sperm production
5. promote the development of masculine secondary sexual characteristics.
▪Androgens→made from cholesterol in the gonads (testes and ovaries) and also in the adrenal glands. The testes produce a significantly higher quantity than the ovaries. They help:
1. create testosterone
2. build skeletal muscle
3. drive libido
4. mediate sperm production
5. promote the development of masculine secondary sexual characteristics.
8/
▪Dehydroepiandrosterone (DHEA)→made from cholesterol, it is a superhormone with:
1. potent anti-aging effects,
2. it improves physical and psychological well-being
3. Increases muscle strength and bone density
4. increases sexual satisfaction
5. increases insulin sensitivity
6. reduces body fat and age-related skin atrophy stimulating procollagen/sebum production.
7. primary precursor of both the androgen and estrogen sex hormones.
8. exerts an immune regulating action, increasing the number of monocytes, “T cells” and “natural killer” cells to fight infection, cancer, and kill dysfunctional and altered cells. 👀
▪Dehydroepiandrosterone (DHEA)→made from cholesterol, it is a superhormone with:
1. potent anti-aging effects,
2. it improves physical and psychological well-being
3. Increases muscle strength and bone density
4. increases sexual satisfaction
5. increases insulin sensitivity
6. reduces body fat and age-related skin atrophy stimulating procollagen/sebum production.
7. primary precursor of both the androgen and estrogen sex hormones.
8. exerts an immune regulating action, increasing the number of monocytes, “T cells” and “natural killer” cells to fight infection, cancer, and kill dysfunctional and altered cells. 👀
9/
▪ Testosterone→made from cholesterol, it is the main sex hormone in males. It plays a key role in:
1. the development and function of the male reproductive tissues,
2 increased skeletal muscle and bone mass
3. decrease body fat mass
4. lowering of the voice
5. development of the Adam’s apple
6. the growth of body hair.
7 increases in libido.
8. in both males and females it is involved in health and well-being, including moods, behavior, and, alongside parathyroid hormone, aids in increasing bone density.
▪ Testosterone→made from cholesterol, it is the main sex hormone in males. It plays a key role in:
1. the development and function of the male reproductive tissues,
2 increased skeletal muscle and bone mass
3. decrease body fat mass
4. lowering of the voice
5. development of the Adam’s apple
6. the growth of body hair.
7 increases in libido.
8. in both males and females it is involved in health and well-being, including moods, behavior, and, alongside parathyroid hormone, aids in increasing bone density.
10/
▪Estrogens→made from cholesterol, it is responsible for:
1. the development and function associated with the female reproductive organs
2. developing female sexual attributes—breast development, body fat increases.
3. reproduction
4. function in the neuroendocrine, vascular, skeletal, and immune systems.
▪Estrogens→made from cholesterol, it is responsible for:
1. the development and function associated with the female reproductive organs
2. developing female sexual attributes—breast development, body fat increases.
3. reproduction
4. function in the neuroendocrine, vascular, skeletal, and immune systems.
11/
◦Neurosteroids→made from cholesterol, include modulation of neural growth and reorganization, learning and memory processes, behavior, as well as responses to stress, anxiety, and depression.
Neurosteroids regulate both regeneration and repair systems in the nervous system, and “allopregnanolone” has been identified as the most significant for its role to promote regeneration in both the central and peripheral nervous systems.
Neurosteroids also play an important role in various gender-specific behaviors and emotional responses.
◦Neurosteroids→made from cholesterol, include modulation of neural growth and reorganization, learning and memory processes, behavior, as well as responses to stress, anxiety, and depression.
Neurosteroids regulate both regeneration and repair systems in the nervous system, and “allopregnanolone” has been identified as the most significant for its role to promote regeneration in both the central and peripheral nervous systems.
Neurosteroids also play an important role in various gender-specific behaviors and emotional responses.
12/
Since your blood is water soluble then in order to transport triglycerides, lipids, and cholesterols in the blood they must be attached to a water soluble component—oils and water DO NOT MIX. These transporting molecules are called lipoproteins.
You have been told they ARE cholesterol but they are NOT. They simply carry cholesterol.
I’m sure you have heard of some do them before
Since your blood is water soluble then in order to transport triglycerides, lipids, and cholesterols in the blood they must be attached to a water soluble component—oils and water DO NOT MIX. These transporting molecules are called lipoproteins.
You have been told they ARE cholesterol but they are NOT. They simply carry cholesterol.
I’m sure you have heard of some do them before
13/
Lipoproteins:
•VLDL: Very Low Density Lipoproteins transport triglycerides (energy) and are made in the liver. VLDL is a large, triglyceride-rich lipoprotein secreted by the liver that transports triglyceride to adipose tissue (fat) and muscle. The triglycerides in VLDL are removed in capillaries (super small blood vessels) by the enzyme “lipoprotein lipase”, and the VLDL returns to the circulation as a smaller particle with a new name, “intermediate-density lipoprotein” (IDL).
Lipoproteins:
•VLDL: Very Low Density Lipoproteins transport triglycerides (energy) and are made in the liver. VLDL is a large, triglyceride-rich lipoprotein secreted by the liver that transports triglyceride to adipose tissue (fat) and muscle. The triglycerides in VLDL are removed in capillaries (super small blood vessels) by the enzyme “lipoprotein lipase”, and the VLDL returns to the circulation as a smaller particle with a new name, “intermediate-density lipoprotein” (IDL).
14/
Lipoproteins:
•IDL particles have lost most of their triglyceride, but they retain cholesteryl esters (necessary chemical shape and function). Some of the IDL particles are rapidly taken back up by the liver; others remain in circulation, where they undergo further triglyceride hydrolysis by hepatic lipase and are converted to LDL.
Lipoproteins:
•IDL particles have lost most of their triglyceride, but they retain cholesteryl esters (necessary chemical shape and function). Some of the IDL particles are rapidly taken back up by the liver; others remain in circulation, where they undergo further triglyceride hydrolysis by hepatic lipase and are converted to LDL.
15/
Lipoproteins:
•LDL: Low Density Lipoproteins can transport anything—cholesterols, triglycerides, and lipids both to the liver from the tissues, and from the liver to the tissues. Notably, LDL particles are thought to act as a major transporter of cholesterol; at least 2/3 of the circulating cholesterol resides in LDL to the peripheral tissues. Conversely, HDL molecules are thought to do the opposite. They take excess cholesterol and return it to the liver for excretion.
Lipoproteins:
•LDL: Low Density Lipoproteins can transport anything—cholesterols, triglycerides, and lipids both to the liver from the tissues, and from the liver to the tissues. Notably, LDL particles are thought to act as a major transporter of cholesterol; at least 2/3 of the circulating cholesterol resides in LDL to the peripheral tissues. Conversely, HDL molecules are thought to do the opposite. They take excess cholesterol and return it to the liver for excretion.
16/
•HDL: High Density Lipoproteins, made in the liver, bring cholesterol from the cell (bound to free radicals, toxins, and waste) back to the liver for processing, as well as cholesterol (precursor building block) from the liver to the adrenals, ovaries, and testes. It also provides anti-oxidative support to LDL and to the cells.
•HDL: High Density Lipoproteins, made in the liver, bring cholesterol from the cell (bound to free radicals, toxins, and waste) back to the liver for processing, as well as cholesterol (precursor building block) from the liver to the adrenals, ovaries, and testes. It also provides anti-oxidative support to LDL and to the cells.
17/
Read this carefully:
Current emphasis on cholesterol as agency, if not cause, of human atherosclerosis and subsequent cardiovascular disease ignores the essentiality of cholesterol in life processes. Additionally ignored is the ubiquitous presence of low levels of oxidized cholesterol derivatives (oxysterols) in human blood and select tissues, oxysterols also implicated in atherosclerosis. Whereas such oxysterols may be regarded putatively as agents injurious to the aorta, an alternative view of some of them is here proposed: that B-ring oxidized oxysterols of human blood represent past interception of blood and tissue oxidants in vivo by cholesterol as an ordinary aspect of oxygen metabolism. Such interception and subsequent efficient hepatic metabolism of oxysterols so formed, with biliary secretion and fecal excretion, constitute as in vivo antioxidant systempubmed.ncbi.nlm.nih.gov/1937129/
Read this carefully:
Current emphasis on cholesterol as agency, if not cause, of human atherosclerosis and subsequent cardiovascular disease ignores the essentiality of cholesterol in life processes. Additionally ignored is the ubiquitous presence of low levels of oxidized cholesterol derivatives (oxysterols) in human blood and select tissues, oxysterols also implicated in atherosclerosis. Whereas such oxysterols may be regarded putatively as agents injurious to the aorta, an alternative view of some of them is here proposed: that B-ring oxidized oxysterols of human blood represent past interception of blood and tissue oxidants in vivo by cholesterol as an ordinary aspect of oxygen metabolism. Such interception and subsequent efficient hepatic metabolism of oxysterols so formed, with biliary secretion and fecal excretion, constitute as in vivo antioxidant systempubmed.ncbi.nlm.nih.gov/1937129/
18/
Lay translation of above:
cholesterol also serves in an antioxidant capacity with its ability to protect tissues and remove lipid soluble toxins, free radicals, and other oxidative molecules away from the cells to be discarded through bile and then your stool—your body helps clean itself out using cholesterol. Having higher amounts of cholesterol is a sign that your body is doing its job when there is oxidative damage, disease, or in need of more hormone production.
Lay translation of above:
cholesterol also serves in an antioxidant capacity with its ability to protect tissues and remove lipid soluble toxins, free radicals, and other oxidative molecules away from the cells to be discarded through bile and then your stool—your body helps clean itself out using cholesterol. Having higher amounts of cholesterol is a sign that your body is doing its job when there is oxidative damage, disease, or in need of more hormone production.
19/
So is cholesterol a good thing, or a bad thing?
»GOOD THING. Having a disease or high oxidative damage indicates you will have higher blood cholesterol levels as your body is trying to REPAIR YOU.
You may have heard of LDL being “bad, and HDL being “good”.
First, LDL is not itself cholesterol, it carries cholesterol, and it certainly is NOT “bad” like you have been told. LDL and HDL, along with VLDL and IDL, are lipoproteins. They function solely to transport triglycerides (energy) and cholesterol (essential building blocks) to and from all parts of the body.
LDL is necessary for your cells to make steroidal hormones from cholesterol. It is also a major contributor to the healing pathways where it not only protects your cells from harmful molecules, but also contributes to the rebuilding, structure, and functioning of your cellular membranes.
Your body is incapable of functioning without LDL. Your body is also incapable of functioning without HDL, VLDL, and IDL.
Since cholesterol is a primary building block, antioxidant, and free radical scavenger, LDL levels will increase in response to toxins, free radical activity, and cellular damage being present and elevated in your tissues—NOT the cause of. This is part of the innate healing, regenerative, and protective processes.
So is cholesterol a good thing, or a bad thing?
»GOOD THING. Having a disease or high oxidative damage indicates you will have higher blood cholesterol levels as your body is trying to REPAIR YOU.
You may have heard of LDL being “bad, and HDL being “good”.
First, LDL is not itself cholesterol, it carries cholesterol, and it certainly is NOT “bad” like you have been told. LDL and HDL, along with VLDL and IDL, are lipoproteins. They function solely to transport triglycerides (energy) and cholesterol (essential building blocks) to and from all parts of the body.
LDL is necessary for your cells to make steroidal hormones from cholesterol. It is also a major contributor to the healing pathways where it not only protects your cells from harmful molecules, but also contributes to the rebuilding, structure, and functioning of your cellular membranes.
Your body is incapable of functioning without LDL. Your body is also incapable of functioning without HDL, VLDL, and IDL.
Since cholesterol is a primary building block, antioxidant, and free radical scavenger, LDL levels will increase in response to toxins, free radical activity, and cellular damage being present and elevated in your tissues—NOT the cause of. This is part of the innate healing, regenerative, and protective processes.
20/
Now that we know and understand all of what cholesterol and the lipoproteins do, ask yourself why do doctors want us to decrease cholesterol through statin medication again?
What would the intake of statins (that reduce cholesterol synthesis in the liver) result in as it pertains to healing, health, hormone levels, immune function, CNS/PNS regeneration/protection, and system wide homeostasis?
Taking a statin to reduce your cholesterol levels means you will significantly decrease your body’s:
1energy production
2mental and physical ability and drive
3sex hormone production
4immune function
5ability to heal and return to homeostasis.
Each of those will have its own progressive and compounding physiological consequences resulting in furthering your dis-ease process.
Now that we know and understand all of what cholesterol and the lipoproteins do, ask yourself why do doctors want us to decrease cholesterol through statin medication again?
What would the intake of statins (that reduce cholesterol synthesis in the liver) result in as it pertains to healing, health, hormone levels, immune function, CNS/PNS regeneration/protection, and system wide homeostasis?
Taking a statin to reduce your cholesterol levels means you will significantly decrease your body’s:
1energy production
2mental and physical ability and drive
3sex hormone production
4immune function
5ability to heal and return to homeostasis.
Each of those will have its own progressive and compounding physiological consequences resulting in furthering your dis-ease process.
• • •
Missing some Tweet in this thread? You can try to
force a refresh
