Layne Norton, PhD Profile picture
Feb 29 10 tweets 3 min read Read on X
How to prevent & recover from injuries/pain?

Yesterday I posted a video of my deadlifting 645 x 3 with relative ease, pain free at 42 years old

This is after I have endured 2 herniated lumbar discs, 2 bulged lumbar discs, 2 herniated cervical discs, torn muscles in both hips, a partially torn pec, & a partially torn adductor over the last 9 years

So how did I do it? Surgery? Special stretches/mobility work? Cold plunges? Stem cells? Peptides?
I did none of those things. I used evidence based pain management & recovery methods

But first off, let's get one thing straight, there is NO SUCH THING as 'injury prevention.'

Even people who are completely sedentary deal with pain & can incur injuries. There are things you can do that can reduce risk of injury but no 'prevention.'

And for athletes who push hard for a long time, injuries & pain are not a matter of 'if' but 'when'
First thing is first. What actually helps reduce risk of injuries? Probably not the things you think

Stretching & increased flexibility has NOT been shown to reduce injury risk (PMIDs: 26642915 & 15782063)

Additionally, 'good form' has little evidence to support injury risk reduction for ex round back lifting did not increase injury risk (PMID: 31775556 & 35098885)

Unfortunately, these have become dogma in the fitness community with virtually no evidence
So what actually does reduce injury risk?

1) Sleep reduces injury risk by up to over 200% when getting 4 h vs. 8 h (PMIDs: 25028798 & 32061551)

2) Psychological stress reduction has been shown to reduce injury risk (PMIDs: 34803856 & 34525450)

3) Repeatable warm up that increases heart rate & body temperature (PMID: 35627873)

4) Belief that you are NOT fragile (PMID: 37240482)
5) Appropriate load/volume management. Training that exceeds recovery increase risk (PMID: 29943231)

Hopefully you have noticed 2 themes: 1) Maximizing recovery and 2) your mental state MATTERS

We used to view the mind & body as separate & if you had pain you must have tissue damage & vice versa

That is a very outdated view of pain. You can have tissue damage & no pain while having pain with no tissue damage (PMIDs: 35669019 & 22341140)
This is known as the Biopsychosocial model of pain & I don't have the space to cover it all but @hubermanlab did a GREAT podcast on it with @DrSeanMackey that I HIGHLY recommend listening to

A classic example is this study in young adults with no back pain: over 50% had disc herniations, annular fissures or nuclear degeneration (PMID: 35669019)!

That's right. They had 'degenerative discs' but absolutely no pain. Pain is more like an emotion that you can sensitize or desensitize yourself to
I'm NOT saying if you break your leg it might not hurt. Pain is a warning system but it can be dysregulated

This is why people can have chronic pain well after any tissue damage should have healed

In fact high levels of stress, inactivity, & poor sleep are strong predictors of chronic pain (PMID: 35061825)

Additionally, expectation of pain, fear, & belief the body is fragile can increase pain sensitivity (PMIDs: 30243037, 23850095, & 27548244)
So how did I heal my injuries? The short answer is I didn't worry about 'healing' them. I managed the pain

I reminded myself continuously that my body is strong & resilient. Just because I have pain does not mean it will last forever. It will not unless I don't manage it

I focused on reducing psychological stress & getting good sleep

I did NOT avoid activity. Avoiding activity increases pain (are you reading orthopedic docs?)
Now, in the short term I did avoid activities & positions that triggered my pain at more than a 4/10 but at minimum I walked or rode the bike & lifted light

But the real game changer for me was exposure therapy. Exposure therapy is where you expose yourself a something causing a SMALL amount of pain & over time you increase the stimulus

Example, I had such terrible hip pain for YEARS that squatting below parallel with almost any weight was unbearable
I started with a high (probably 6" above parallel) squat to pins at a slow tempo with a pause at about 80% of the load I could probably do if I went all out. It triggered a small amount of pain. Each week I added weight or lowered the pains as the pain allowed

After 16 weeks I was back to doing full heavy squats to depth with almost NO PAIN. Recovery was NOT linear & there were weeks I had to back off but I simply told myself I was resilient & did not catastrophize setbacks

That's why at age 42, I am mostly pain free & strong AF

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More from @BioLayne

Feb 15
I recently got in trouble for saying that hormones & menopause don't really change what works for fat loss

This led to a brigade of people & a popular influencer doc (who sells 'special' programs to menopausal women) to attack me

I've been called insensitive, a misogynist, & told I can't speak on women's research since I'm a man

I'm not a woman, but I can read research. So let's look at the data
To be clear, I never said fat loss was not more difficult post-menopausal, I just said the rules didn't change

Lifestyle choices will still override menopausal induced changes, but they can be more difficult to implement

So let's look at the literature. First, we do see that menopause induces changes in body composition

We DO see decreases in lean mass & increases in fat mass during menopause (PMID: 34898344)
However, these changes appear similar with age regardless of menopausal status (PMID: 37265230)

That is, body composition changed similarly across the years of menopause as it did during aging in adult women for the non-menopause years

We do know that lean mass (LM) declines with aging & this appears to explain the differences in basal metabolic rate (BMR)

Does menopause uniquely reduce BMR though?
Read 11 tweets
Feb 8
I talk a lot about losing weight, but what about those who are skinny & want to gain weight & muscle?

The vast majority of people focus on fat loss, but for people who grew up skinny like me, gaining felt hard

Do you want to gain weight?

Mostly muscle?

Here are my top tips
Obviously, the most important thing for gaining muscle is appropriate resistance training

I could do an entire swipe series on that but in short

You need to train with enough intensity (close to failure), high or low reps seem to be equally effective

You need to do enough hard sets (volume)

You have to do it consistently over time
The focus of this post is nutrition, so what is most important?

Like in weight loss, calorie balance is most important for gaining weight

You have to be in a calorie surplus to add weight but you don't have to be in a surplus to gain muscle

But, it is likely easier to gain muscle in a surplus vs a deficit/maintenance (PMID: 31915482 & 34623696)
Read 10 tweets
Jan 11
Are vegan meals really equivalent to omnivore meals for anabolism?

A new study compared muscle protein synthesis (MPS) for vegan vs omnivore meals in elderly (PMID: 37972895)

This study was unique in that it almost perfectly matched macros & protein

The results were striking
They found that the omnivore group had ~47% greater MPS area under the curve (AUC)

Plasma leucine response AUC was 139% greater in omnivore

Total EAA AUC was also about 2x more for omnivore

This seems contrary to other research showing no difference

Why such a difference?
Probably the biggest distinction is this study was in elderly

Elderly require a greater amount of leucine/EAA to stimulate MPS (PMID: 15596483)

Further, this study used whole food sources whereas others used isolated proteins

Whole food plant proteins are less bioavailable
Read 7 tweets
Dec 21, 2023
EAT POOP TO LOSE FAT!

Do I have your attention?

In this post I'm going to explain why people get sucked into believing BS from influencers who claim to be 'science based'

These are the most insidious of scammers because they wear the veil of 'science' while being full of it
These are people pick a certain compound found in foods or elsewhere are either 'toxic' or miracle cures

Looking at you "vegetables are toxic" crowd

Can you find chemical compounds present in vegetables that if you fed high amounts would be toxic?

Sure, but that means f*** all
I can find compounds in ANY food that can make an argument for consuming or avoiding said food

In fact, I've said I bet I could make a compelling argument for eating sh*t & support it with citations

So that is what I'm going to do

Pay attention because this is their template
Read 10 tweets
Dec 15, 2023
42 years old today & probably about halfway done with this ride (hopefully a bit less than half 😬)

Overall I’ve really enjoyed it

I’ve had hard times like anyone but overall I’m very grateful

Here are a few things I’ve learned
that I wish I knew when I was younger
1) SLOW DOWN

Man, over 50% of my problems would never have occurred if I just slowed down

So many people try to rush the process not realizing that good things take TIME

I created so much more stress but not dotting my i’s & crossing my t’s

Slow is smooth, smooth is FAST
2) Everyone should NOT like you

If everyone likes you, it means you are an amoeba & have no backbone

Being horribly bullied growing up I had such bad fear of no one liking me, so I tried to get everyone to like me

The amount of pain & mistakes this led me to are incalculable
Read 10 tweets
May 25, 2023
Building muscle is not complicated but it does take hard work & patience

Here are the biggest things you NEED to know

In order to increase muscle mass you need to progressively overload your muscles

This sounds simple but executing that can be more difficult
Progressive overload can take several forms:

1) Adding more weight to an exercise. As you get stronger you add more weight & more mechanical tension to muscles

2) Increase reps on the sets for an exercise. More reps = more mechanical tension

3) Increasing number of hard sets
Increasing weight & reps are intuitive, but what does increasing 'number of hard sets' mean?

Firstly, we believe the main driver of hypertrophy is mechanical tension (MT)

Increasing weight lifted or number of reps increases MT

MT is also cumulative over multiple sets
Read 9 tweets

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