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Noha Aboelata, MD Profile picture
Mar 17 11 tweets 2 min read Read on X
The latest wave of covid propaganda is to claim that ~covid anxiety~ is the biggest pandemic problem we're facing. I have yet to see the data. I have, on the other hand, seen mountains of data indicating structural and functional changes to heart, lungs, brain, and more. 🧵
"But same with the flu!"

No. Via ACE receptors and otherwise, SARS-CoV-2 can affect every system, even damage inside blood vessels (yes the tubes that deliver blood everywhere). True, we've likely under-appreciated post-influenza sequelae. Still, it seems less and fewer organs.
Did the rapidly spreading airborne virus killing people all around us scare folks? Ummm, yes. People's experiences, reactions, and coping mechanisms are diverse. Some lost loved ones, experienced hospitalization/ICU, gained new chronic health issues. Children lost their parents.
Others lost jobs, got off-track with their education, got behind on the basics.

If you're behind on preventative health, cancer screenings, labwork, please catch up! Knowledge = power.

If you need someone to talk to, please find someone.

Also, check on your people.
As for how we're living now, there are those with zero regard for covid risk, and there are those who continue to mitigate it (to varying degrees of course). We know there are layers of protection, and the more layers, the better. Mask, vax, gather outside, test, isolate when +.
The best intervention we can do as a society is create & maintain high standards for indoor ventilation/air exchange/filtration, especially important in schools & congregate settings, with transparency like the restaurant letter grade! Create more safe outdoor gathering spaces.
Protecting yourself is a personal choice. It's a choice that can affect others mainly because C19 is airborne and highly contagious, and because asymptomatic transmission occurs. So a filtration mask is currently our best bet for individual protection when there may be exposure.
Trying to shoo away long covid by insulting those experiencing it is trash. The lack of evidence thus far is noted. Data that "will be presented" at the such-and-such conference is dead to me. Wake me up when the peer reviewed article is published and then we'll talk.
This trash take is also insulting to all the real researchers who've published actual findings. I hope your peer reviewed studies cite them well and explain how your research contributes. If you really care about covid-era behavioral health challenges, let's hear your plan.
We still have a lot to learn and a ways to go - it's still early! The more we can quantify and understand, the better we can evolve and tailor our interventions. I hope for better vaccines, better treatments, better diagnostics, and significant advancements in long & post-covid.
Until then I'm continuing to mask, strategically test, gather outdoors as much as possible, improve indoor ventilation/filtration wherever I can, and improve my own understanding through reading the literature and listening to patients and to experts in their respective fields. /

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More from @NohaAboelataMD

Mar 10
Metformin & Covid. Metformin is widely used, accessible/cheap, and has been around for decades, so we'd love if it could help in our ongoing struggles with covid. So far it looks promising to prevent long covid, and those already on it should continue it during acute c19 infxn.🧵
In the COVID-OUT trial (multicenter randomized quadruple-blind parallel-group phase 3 trial), in 30-85yo's w/"overweight or obesity," Metformin cut the risk of long Covid by ~41%. And when started within 3 days of Covid symptoms, it reduced the incidence of long COVID by ~63%!
Can this be generalized to those not 30-85 or those without "overweight or obesity?" More study is needed, but for those who do fit the criteria, it is certainly compelling.

*Metformin, Ivermectin, or fluvoxamine did not reduce severe acute C19 outcomes. thelancet.com/journals/lanin…
Outpatient treatment of COVID-19 and incidence of post-COVID-19 condition over 10 months (COVID-OUT): a multicentre, randomised, quadruple-blind, parallel-group, phase 3 trial Carolyn T Bramante, MD  Prof John B Buse, PhD David M Liebovitz, MD Jacinda M Nicklas, MD Michael A Puskarich, MD Ken Cohen, MD et al. Published:June 08, 2023 DOI:https://doi.org/10.1016/S1473-3099(23)00299-2
Read 8 tweets
Feb 4
It's sad to see so much venom towards scientists, doctors, and covid-careful individuals on this app - one of the reasons so many have left. I left FB because it became a cesspool of disinformation, and I was impressed with the quality info direct from scientists and docs here.🧵
Having a common enemy - a mutating virus infecting, sickening, and killing so many - should have brought us together. And I think it did for a brief moment. Then, it became highly politicized, and bad actors exploited folks' uncertainty, unfamiliarity, and fear.
And yes, there were many policies and interventions that were polarizing. We can Monday morning quarterback it forever, but we'll never all agree on the right balance between individual freedom and collective responsibility. Sadly, we seem further apart on this point than ever.
Read 11 tweets
Jan 28
Despite baked-in racial bias, pulse oximeters continue to be relied upon for covid, qualifying for home oxygen, and more. They're used at home, on ambulances, in clinics and hospitals. The FDA is aware but moving slowly, which is why we filed a lawsuit.🧵
nature.com/articles/d4158…
Image
This lawsuit demands pulse ox manufacturers/distributors fix the devices, label them as to their flaws, or stop selling them in California. But even if we're successful, this doesn't extend beyond CA, and the FDA can continue approving faulty devices as they've done for decades.
No doubt, this flaw has resulted in morbidity and mortality, especially at the height of the pandemic when beds and oxygen were not always available. Yet the device continues to be used and can lead to denial of home oxygen among other treatments. We should all be outraged. 3/6
Read 6 tweets
Jan 23
Thank you, @DrJudyStone and @Forbes for interviewing me for this fantastic article about California's shocking move, recklessly encouraging contagious people to go unmasked into schools and pubic places - in the middle of winter no less! 🧵1/4
forbes.com/sites/judyston…
Just 1 contagious child can infect many more in 1 day, let alone coming to school contagious many days in a row! The order admits that the contagious period begins 2 days before symptoms start through 10 days after. There's a buried *recommendation* to mask x 10d. Seriously? 2/4
More platitudes about being "in a better place" and having "the tools" mean little when we still have a mutating virus, worrisome impacts of repeat infection, undervaccination and no real treatment for kids. What's it about? Is this really about improving school attendance? 3/4
Read 4 tweets
Jan 20
Thanks, @CalMatters, for interviewing me about these wild new "guidelines" encouraging contagious people to get back to school and work, despite our ability to easily test and prevent much unnecessary spread. Promoting reckless disregard for everyone.🧵1/8
calmatters.org/health/2024/01…
“'Instead of staying home for a minimum of five days, individuals may return to work or school when they start to feel better,' state public health officials said in an unsigned statement."

I wouldn't want to sign it either. 2/
The notion that this is reasonable as long as we're careful around vulnerable people is just 🤯. How do you know who's immunocompromised? What about vulnerable household members? This policy will surely level the playing field - we'll all be made vulnerable at this rate. 3/
Read 8 tweets
Jan 19
I haven't said anything about this yet - at first, it was because I was speechless. Then I hoped no one would notice. Now that advocates, reporters, concerned parents, and outraged colleagues have reached out, I see that's not going to be the case.🧵1/7
ktla.com/news/californi…
Contagious people are being encouraged to go to work/school. This decision is not evidence-based, and it clearly does not consider the impacts of long covid, the need for people to rest and recover when sick, or the ramifications of increased transmission such as new variants. 2/
The consistent dialing back of precautions every time we think we're in "a better place" is what keeps up from actually getting to a better place. Zero mention of the burden of repeat infection or risk of long covid. I wonder if they listened to Dr. @zalaly's brilliant testimony.
Read 7 tweets

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