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Noha Aboelata, MD Profile picture
@NohaAboelataMD
Mar 28 • 4 tweets • 2 min read • Read on X
Post-covid vs post-flu: retrospective study based on a global research network investigates post-infection conditions, long-term risk of ED visits, hospitalization & death. Looked at 6614 patients in each group hospitalized 1/22-1/23 w/90-180d followup. 🧵
doi.org/10.1186/s12916…
Comparison of post-acute sequelae following hospitalization for COVID-19 and influenza
The Covid group had a higher incidence of overall post-infection conditions compared to the influenza group, including a difference in what each group was experiencing. The Covid group had more abnormal breathing, more abdominal issues, more fatigue, and more cognitive issues. Comparison of post-acute sequelae following hospitalization for covid-19 and influenza
The COVID group also had a significantly higher risk of the composite outcomes during all-cause ED visits, hospitalizations & deaths compared with the flu group.

--> Hospitalized COVID patients are at higher risk of long-term complications when compared with influenza survivors.
A couple of caveats/notes:
- This is about hospitalized people and may not generalize to mild-mod infections.
- We've been dealing with SARS-CoV-2 for much less time. Hopefully we'll gain a better grasp and succeed in reducing post-covid sequelae.
- we still have lots to learn!

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More from @NohaAboelataMD

Noha Aboelata, MD Profile picture
Mar 22
Prop. 1 will help the state fully implement:
- a new court system for those with mental illness, even if no crime has been committed
- the recent CA law making it easier to force some with serious mental illnesses into involuntary treatment. 🧵
calmatters.org/health/mental-…
With Prop. 1 passage, Gavin Newsom again changes how Californians with mental illness get help
The plan seems to be to force *more* people into a system that's already overstretched. To layer in the court system, which is already biased. To empower lay people to compel the court to force individuals into treatment for mental illness, substance use, even chronic alcoholism.
Criminalization of mental illness can now be fully mainstreamed. This "pre-crime" paradigm represents an erosion of civil rights, and we're sure to see the same dramatic overrepresentation of especially African American men seen in all parts of the criminal legal system.
Read 6 tweets
Noha Aboelata, MD Profile picture
Mar 17
The latest wave of covid propaganda is to claim that ~covid anxiety~ is the biggest pandemic problem we're facing. I have yet to see the data. I have, on the other hand, seen mountains of data indicating structural and functional changes to heart, lungs, brain, and more. 🧵
"But same with the flu!"

No. Via ACE receptors and otherwise, SARS-CoV-2 can affect every system, even damage inside blood vessels (yes the tubes that deliver blood everywhere). True, we've likely under-appreciated post-influenza sequelae. Still, it seems less and fewer organs.
Did the rapidly spreading airborne virus killing people all around us scare folks? Ummm, yes. People's experiences, reactions, and coping mechanisms are diverse. Some lost loved ones, experienced hospitalization/ICU, gained new chronic health issues. Children lost their parents.
Read 11 tweets
Noha Aboelata, MD Profile picture
Mar 10
Metformin & Covid. Metformin is widely used, accessible/cheap, and has been around for decades, so we'd love if it could help in our ongoing struggles with covid. So far it looks promising to prevent long covid, and those already on it should continue it during acute c19 infxn.🧵
In the COVID-OUT trial (multicenter randomized quadruple-blind parallel-group phase 3 trial), in 30-85yo's w/"overweight or obesity," Metformin cut the risk of long Covid by ~41%. And when started within 3 days of Covid symptoms, it reduced the incidence of long COVID by ~63%!
Can this be generalized to those not 30-85 or those without "overweight or obesity?" More study is needed, but for those who do fit the criteria, it is certainly compelling.

*Metformin, Ivermectin, or fluvoxamine did not reduce severe acute C19 outcomes. thelancet.com/journals/lanin…
Outpatient treatment of COVID-19 and incidence of post-COVID-19 condition over 10 months (COVID-OUT): a multicentre, randomised, quadruple-blind, parallel-group, phase 3 trial Carolyn T Bramante, MD Prof John B Buse, PhD David M Liebovitz, MD Jacinda M Nicklas, MD Michael A Puskarich, MD Ken Cohen, MD et al. Published:June 08, 2023 DOI:https://doi.org/10.1016/S1473-3099(23)00299-2
Read 8 tweets
Noha Aboelata, MD Profile picture
Feb 4
It's sad to see so much venom towards scientists, doctors, and covid-careful individuals on this app - one of the reasons so many have left. I left FB because it became a cesspool of disinformation, and I was impressed with the quality info direct from scientists and docs here.🧵
Having a common enemy - a mutating virus infecting, sickening, and killing so many - should have brought us together. And I think it did for a brief moment. Then, it became highly politicized, and bad actors exploited folks' uncertainty, unfamiliarity, and fear.
And yes, there were many policies and interventions that were polarizing. We can Monday morning quarterback it forever, but we'll never all agree on the right balance between individual freedom and collective responsibility. Sadly, we seem further apart on this point than ever.
Read 11 tweets
Noha Aboelata, MD Profile picture
Jan 28
Despite baked-in racial bias, pulse oximeters continue to be relied upon for covid, qualifying for home oxygen, and more. They're used at home, on ambulances, in clinics and hospitals. The FDA is aware but moving slowly, which is why we filed a lawsuit.🧵
nature.com/articles/d4158…
Image
This lawsuit demands pulse ox manufacturers/distributors fix the devices, label them as to their flaws, or stop selling them in California. But even if we're successful, this doesn't extend beyond CA, and the FDA can continue approving faulty devices as they've done for decades.
No doubt, this flaw has resulted in morbidity and mortality, especially at the height of the pandemic when beds and oxygen were not always available. Yet the device continues to be used and can lead to denial of home oxygen among other treatments. We should all be outraged. 3/6
Read 6 tweets
Noha Aboelata, MD Profile picture
Jan 23
Thank you, @DrJudyStone and @Forbes for interviewing me for this fantastic article about California's shocking move, recklessly encouraging contagious people to go unmasked into schools and pubic places - in the middle of winter no less! 🧵1/4
forbes.com/sites/judyston…
Just 1 contagious child can infect many more in 1 day, let alone coming to school contagious many days in a row! The order admits that the contagious period begins 2 days before symptoms start through 10 days after. There's a buried *recommendation* to mask x 10d. Seriously? 2/4
More platitudes about being "in a better place" and having "the tools" mean little when we still have a mutating virus, worrisome impacts of repeat infection, undervaccination and no real treatment for kids. What's it about? Is this really about improving school attendance? 3/4
Read 4 tweets

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