Sometimes, good, important studies don't receive enough attention or coverage in the media.
Often, people associate #LongCovid as a disease that is only present in previously immunocompromised or older people. This is not true.
This study did a comprehensive clinical assessment
of more than 200 patients, previously well, working-age adults in full-time employment, aged 39-47, evaluated 24 weeks after recovering from #COVID_19.
Results: 69% reported ≥3 ongoing symptoms. Shortness of breath (61%), fatigue (54%) and cognitive problems (47%) were the most frequent symptoms,
One-third of lung function tests were abnormal (reduced lung volume and transfer factor, and obstructive spirometry).
17% met criteria for anxiety and 24% depression.
67% remained below pre-COVID performance status at 24 weeks.
Conclusion: Despite low rates of residual cardiopulmonary pathology, in this cohort, with low rates of premorbid illness, there is a high burden of symptoms and failure to regain pre-COVID performance 6-months after acute illness.
Cognitive assessment identified a specific deficit of the same magnitude as intoxication at the UK drink driving limit or the deterioration expected with 10 years ageing, which appears to contribute significantly to the symptomatology of long-COVID.
Often, people associate #LongCovid as a disease that is only present in previously immunocompromised or older people. This is not true.
This study did a comprehensive clinical assessment
of more than 200 patients, previously well, working-age adults in full-time employment, aged 39-47, evaluated 24 weeks after recovering from #COVID_19.
Results: 69% reported ≥3 ongoing symptoms. Shortness of breath (61%), fatigue (54%) and cognitive problems (47%) were the most frequent symptoms,
One-third of lung function tests were abnormal (reduced lung volume and transfer factor, and obstructive spirometry).
17% met criteria for anxiety and 24% depression.
67% remained below pre-COVID performance status at 24 weeks.
Conclusion: Despite low rates of residual cardiopulmonary pathology, in this cohort, with low rates of premorbid illness, there is a high burden of symptoms and failure to regain pre-COVID performance 6-months after acute illness.
Cognitive assessment identified a specific deficit of the same magnitude as intoxication at the UK drink driving limit or the deterioration expected with 10 years ageing, which appears to contribute significantly to the symptomatology of long-COVID.
"Participants in this study had a reduction in fluid composite T-score of 4.7, p = 0.001, this is equivalent to a 7-point reduction on a standard IQ test and is of similar magnitude to the reduction seen in cognitive performance whilst intoxicated at the UK/US drink driving limit (80 mg/100 mL blood or 35 mcg/100 mL breath) or that seen with 10 years of normal ageing."
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