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T. Ryan Gregory Profile picture
@TRyanGregory
Apr 6 • 2 tweets • 1 min read • Read on X
I suppose it's time to start "fearmongering" about avian flu. So, here goes. 🧵

* Stop minimizing infectious diseases.

* Stop pathologizing people's legitimate concerns about avoiding infection.

* Normalize taking reasonable precautions.

* Clean the air indoors, FFS.

1/
* Stop platforming people who are have been wrong repeatedly and merely deal hopium.

* Global vaccine equity. No more rich countries hoarding and wasting vaccines.

* Be proactive, not constantly reactive.

* Give accurate information about mode of transmission from the start.

• • •

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More from @TRyanGregory

T. Ryan Gregory Profile picture
Apr 4
The best we get now is *relative* lows. Here are numbers of hospital patients with COVID in Canada. It's as low as it has been since the first Omicron wave (early 2022), on par with the relative lull of mid-summer 2023. But still much higher than summer 2020 and summer 2021. Hospitalizations in Canada
*Maybe* it will continue to drop as thr weather warms and if there are no new major variants that displace JN.1* in the meantime (fingers crossed, and wastewater signal is low), but the reality is that the baseline has never come back down in Canada post-Omicron.
Relative lows do not mean no risk, they mean less risk. If you've been putting off doing things while cases were higher, a relative low is a better (but again, not risk-free) time to do them than during a relative high, obviously.

Read 4 tweets
T. Ryan Gregory Profile picture
Mar 4
Let's be clear about what happened here. 🧵

1. Israeli real estate companies held Jews-only events to sell land in Israel and contested (Jerusalem) or occupied (West Bank) territories in Palestine.

1/
Note that some of the events are taking place in synagogues and some include properties that are within the illegally occupied West Bank. Other events have been held at public venues.

2/
2. Politicians preemptively labelled planned protests of events being held at synagogues as antisemitic.



3/
Read 14 tweets
T. Ryan Gregory Profile picture
Feb 7
Measles touted as an example of the effectiveness of working out one's immune system muscle.

A few reminders about measles...

🧵 "For some bugs, once you've fought it once, your muscles are so strong against it they may never need another work out to fend it off (e.g. measles, smallpox"
Measles has been known for 1,000 years and it still hasn't evolved to be benign.

pubmed.ncbi.nlm.nih.gov/36414136/
Measles can cause "immune amnesia", wiping out immunity to other pathogens.

(This was discovered only a few years ago. The measles virus was identified in 1954 and the disease has been described since the 9th century.)

bbc.com/future/article…
Read 7 tweets
T. Ryan Gregory Profile picture
Feb 4
Now that Pirola clan (BA.2.86 and descendants, most notably JN.1*) is the dominant variant lineage globally, the question arises as to whether it might undergo recombination with earlier XBB lineages.

Yep. Already has.

🧵
So far...

Pirola x Arcturus:
XDK = JN.1.1.1 x XBB.1.16.11

Pirola x Eris:
XDD = JN.1 x EG.5.1.1
XDS = JN.3.2.1 x EG.5.1.3

Pirola x Kraken:
XDN = JN.1. x JD.1*
XDR = JN.1.1 x JD.1.1.1

Pirola x Hyperion:
XDP = JN.1.4 x FL.15
Reminder of how recombination occurs.

Read 8 tweets
T. Ryan Gregory Profile picture
Feb 1
Here are some excellent threads about more highly divergent BA.2 lineage variants showing up after having evolved within a single host with a chronic infection. Within-host evolution is going to be an increasingly important issue.

🧵
Read 6 tweets
T. Ryan Gregory Profile picture
Jan 28
Whoa. Japan. Small samples, but obviously do not want an HK.3 wave on top of JN.1 or even just a sustained high baseline.

Reminder:

JN.1 (Pirola clan) = BA.2.86.1.1

HK.3 (Eris + FLip) = EG.5.1.1.3
asahi.com/ajw/articles/1…
From August:

Read 5 tweets

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