The American Academy of Pediatrics and the Endocrine Society, the two most influential US medical societies in pediatric gender medicine, have issued their first known statements on England's Cass Review on the subject, to @WBUR's @OnPointRadio:
STATEMENT FROM AMERICAN ACADEMY OF PEDIATRICS: Statement from American Academy of Pediatrics President, Dr. Ben Hoffman:
“The AAP’s gender -affirming care policy, like all our standing guidance, is grounded in evidence and science. Pediatricians understand the complexities of gender-affirming care and they know how to counsel families. The goal is not a certain treatment or timeline, but instead to listen to the patient and create a safe environment to address their needs. “What we’re seeing more and more is that the politically infused public discourse is getting this wrong — and it’s impacting the way that doctors care for their patients.
Physicians must be able to practice medicine that is informed by their medical education, training, experience, and the available evidence, freely and without the threat of punishment. Instead, state legislatures have passed bills to ban and restrict gender-affirming care, which means that right now, for far too many families, their zip code determines their ability to seek the health care they need. Politicians have inserted themselves into the exam room, and this is dangerous for both physicians and for families.”
Here is the Endocrine Society's statement on the Cass Review, given to @WBUR's @OnPointRadio. In short, "Medical evidence, not politics, should inform treatment decisions."
STATEMENT FROM ENDOCRINE SOCIETY: We stand firm in our support of gender-affirming care. Transgender and gender-diverse people deserve access to needed and often life-saving medical care.
NHS England’s recent report, the Cass Review, does not contain any new research that would contradict the recommendations made in our Clinical Practice Guideline on gender-affirming care.
The guideline, which cites more than 260 research studies, recommends a very conservative approach to care, with no medical intervention prior to puberty. Estimates indicate only a fraction of transgender and gender-diverse adolescents opt to take puberty-delaying medications, which have been used to treat early puberty in youth for four decades.
• The guideline recommends beginning treatment with puberty-delaying medications that are generally reversible.
• As adolescents grow older and can provide informed consent, then hormone therapy can be considered.
• Our guideline suggests waiting until an individual has turned 18 or reached the age of majority in their country to undergo gender-affirming genital surgery.
Medical evidence, not politics, should inform treatment decisions.
Our Clinical Practice Guidelines are developed using a robust and rigorous process that adheres to the highest standards of trustworthiness and transparency as defined by the Institute of Medicine (now the National Academy of Medicine).
Our guideline development panels spend years developing each guideline based on a thorough review of medical evidence, author expertise, rigorous scientific review, and a transparent process.
More than 18,000 Endocrine Society members worldwide have an opportunity to comment on guideline drafts prior to publication.
The Society is in the process of updating the 2017 Clinical Practice Guideline. It was one of six selected for a routine update.
The process will incorporate the latest research and conduct systematic reviews to provide guidance on the safe and effective treatment of gender incongruence and dysphoria from an endocrine perspective.
We agree that increased funding for youth and adult transgender health research programs is needed to close the gaps in knowledge regarding transgender medical care and should be made a priority.
Although the scientific landscape has not changed significantly, misinformation about gender-affirming care is being politicized.
In the United States, 24 states have enacted laws or policies barring adolescents’ access to gender-affirming care, according to the Kaiser Family Foundation. In seven states, the policies also include provisions that would prevent at least some adults over age 18 from accessing gender-affirming care.
Cisgender teenagers, together with their parents or guardians, are deemed competent to give consent to various medical treatments.
Teenagers who have gender incongruence and their parents and guardians should not be discriminated against.
Transgender and gender-diverse teenagers, their parents, and physicians should be able to determine the appropriate course of treatment.
Banning evidence-based medical care based on misinformation takes away the ability of parents and patients to make informed decisions.
Medical evidence, not politics, should inform treatment decisions.
The @AmerAcadPeds never responded to @JamesCantorPhD's scathing fact check of its 2018 policy statement on the affirmative care model for gender distressed children. Instead, it reaffirmed the policy statement in Aug 2023 with no changes. ohchr.org/sites/default/…
The AAP is subject to a lawsuit from a detransitioner, as I wrote for the @NewYorkSun: nysun.com/article/lawsui…
The AAP has become increasingly secretive about its work on the subject of gender distressed children. nysun.com/article/sued-o…
In its statement to @WBUR, the Endocrine Society says that "only a fraction" of gender distressed children receive medical transition. This after @WPATH said in a statement responding to the Cass Review that the majority of such children would do better to medically transition.
@chadfelixg Harvard Law School clinical instructor and trans activist Alejandra Caraballo is unhappy about @BenAppel’s article in @TheAtlantic, calling it the “‘they're transing the gays’ conspiracy theory.”
"The science doesn’t seem so settled after all, and it’s important to understand what happened here. The approach of left-of-center Americans and our institutions — to assume that when a scientific organization releases a 'policy statement' on a hot-button issue, that the policy statement must be accurate — is a deeply naïve understanding of science, human nature and politics, and how they intersect," writes @JesseSingal for @NYTOpinion.
The A.P.A. presents a particularly striking case of why transparency is important. In 2024, it published what it touted as a “groundbreaking policy supporting transgender, gender diverse, nonbinary individuals” that was specifically geared at fighting “misinformation” on that subject. But when I reached out to the group this month, it pointed me to a different document, a letterwritten by the group’s chief advocacy officer, Katherine McGuire, in September in response to a Federal Trade Commission request for comment on youth gender medicine.
The documents, separated by about a year and a half (and, perhaps as significantly, one presidential election), straightforwardly contradict each other. The A.P.A. in 2024 argued that there is a “comprehensive body of psychological and medical research supporting the positive impact of gender-affirming treatments” for individuals “across the life span.” But in 2025, the group argued that “psychologists do not make broad claims about treatment effectiveness.”
In 2024, the A.P.A. criticized those “mischaracterizing gender dysphoria as a manifestation of traumatic stress or neurodivergence.” In 2025, it cautioned that gender dysphoria diagnoses could be the result of “trauma-related presentations” rather than a trans identity, and noted that “co-occurring mental health or neurodevelopmental conditions (e.g., depression, anxiety, autism spectrum disorder) … may complicate or be mistaken for gender dysphoria.” It seems undeniable that the 2025 A.P.A. published what the 2024 A.P. A considered to be “misinformation.” (“The 2024 policy statement and the 2025 F.T.C. letter are consistent,” said Ms. McGuire in an email, and “both documents reflect A.P.A.’s consistent commitment to evidence-based psychological care.”)
@nytopinion @jessesingal Jesse Singal on youth gender medicine in @NYTOpinion: “I’ve been covering this controversy for about a decade from a left-of-center perspective, and I’ve found that anyone who questions these treatments, even mildly, is invariably accused of bigotry.”
NEWS: Mt. Sinai, the sprawling hospital system, has joined NYU Langone in shuttering its pediatric gender clinic in the face of threats from the Trump administration of cutting off its Medicaid funding.
NYC Mayor Zohran Mamdani @ZohranKMamdani @NYCMayor pledged in his campaign to spend $65M in city funds on gender-transition treatment to evade pressures from the Trump administration to cut off such access. But since NYU announced it would no longer provide gender-transition drugs or surgeries to minors, the mayor has been mum on the potential for spending public funds on these interventions.
The blue-state pediatric gender clinic closures started with Children's Hospital Los Angeles last July and have continued steadily since then. benryan.substack.com/p/dr-johanna-o…
YouTube sleuths found: @TaylorLorenz apparently copied substantial portions of a TechDirt article about Joseph Gordon-Levitt @hitRECordJoe and Section 230.
Lorenz appeared to pass off the article's text as if it was her own script.🧵⬇️
Go to 4:22 in this video to see the part where the YouTube hosts assert that @TaylorLorenz has plagiarized her narration from a TechDirt article about Joseph Gordon-Levitt @hitRECordJoe and Section 230: youtube.com/live/JXI9uRwfG…
I can’t even begin to enumerate all the nasty things Parker Molloy has said about me in an effort to punish me for reporting about pediatric gender medicine and to scare off other reporters who might dare to enter this arena. My policy with responding to such behavior is I report what people such a Molloy say or do, and will often fact check errors. They then turn around and make vicious and demeaning claims about who I am.
The Federal Trade Commission has opened a consumer protection probe into the American Academy of Pediatrics and has demanded its records regarding pediatric gender medicine.
In 2018, the AAP published its foundational policy document on the gender-affirming care method. It was written by a single medical resident, Dr. Jason Rafferty, and edited by a small committee. It was subjected to a brutal fact check by Canadian sex researcher Dr. James Cantor the following year. The AAP never responded to the fact check. In 2023, the AAP reaffirmed the policy statement with no changes.
The statement asserts that even very young children know their gender identity as well as anyone and should be trusted to guide the way in their own pathway of transition.