Yes the virus emerged in Wuhan & the WIV is there & studies SARS-related CoVs, but that’s where the truth ends.
Shi Zhengli’s lab does great work on SARSr-CoVs, but they aren’t the only lab in the world doing so. They aren’t even the only lab in China doing this work.
In fact, people all over the world have been studying these viruses—including those isolated from bats—since SARS1 emerged in 2002. In the US, Australia, Hong Kong, Singapore, the UK, the Netherlands, Japan, France, Canada, and so on.
Fun fact: early in 2020 I joined a WHO Expert Group on experimentally modeling SARS-CoV-2. Multiple folks from China were there, none of whom were from WIV or Wuhan. SARS-CoV-1 emerged in China, so many labs there study these viruses. Wuhan isn’t special & WIV is one of many.
This is a little confusing, since the “defining feature” isn’t actually defined by the author. But she means the furin cleavage site.
She also neglects to mention this proposed work was not funded (thus likely didn’t occur) & all the FCS insertion work was to occur in the US.
And could this work have been done despite the multimillion dollar grant intended to support it? Sure. Is there evidence that this work was carried out anyway?
None whatsoever.
Most people don’t apply for DARPA grants they don’t need if they already have millions lying around
Yes the WIV did SARSr-CoV work at BSL-2 (consistent with the BMBL, the US’s standards for bat SARSr-CoVs).
No, this isn’t appropriate for SARS-CoV-2.
However, there is zero evidence that WIV had SARS-CoV-2 or a progenitor in their collection.
No SARS2 at WIV, no lab leak.
That’s pretty simple. It doesn’t matter what containment level the WIV was using for other SARSr-CoVs because those viruses are not SARS-CoV-2, nor could these viruses ever become SARS-CoV-2.
The viruses that WIV was known to have are more closely related to SARS-CoV-1.
Even the most closely related SARSr-CoV (RaTG13) in WIV’s collection is different by more than 1100 mutations across its entire genome. No amount of insertions, mutagenesis, or passaging in cells, transgenic mice, bats, or whatever else can make it SARS-CoV-2.
I’m closely related to my sibling and my parents. If I got cancer or HIV (which would cause mutations/insertions/recombination of my genome), it would not turn me into my brother or my parents.
Similarly, the WIV’s SARSr-CoVs can’t turn into SARS-CoV-2 at any containment level.
This is just plain incorrect. The hypothesis was published with enough supporting evidence to pass a rigorous peer review and be published in Science. The papers have not been retracted.
And just because a small but outspoken group of people—primarily those without any relevant professional or domain expertise, including the author of the NYT piece—claim these papers are disputed, debunked, or aren’t “strong” evidence doesn’t make those claims true.
If anyone can provide a legitimate analysis or plausible alternative explanation for these multiple threads of evidence, then they should submit it for peer review by experts and publish it in a scientific journal.
So far no such paper has been produced.
Here’s a summary of the Worobey et al 2022 paper.
Critics have had 2 years to challenge these results scientifically, providing additional evidence or a compelling alternative interpretation of these data. These papers & their findings have not been substantively challenged.
Finally, no shit “key evidence” is still missing. The role of the market in the pandemic’s emergence was covered up in ways that didn’t apply to SARS1 or MERS. The market was closed. Live animals were removed. Clearly evidence was suppressed, not collected, or not made accessible
However, that doesn’t mean the evidence we DO have doesn’t support market origin. Existing affirmative evidence isn’t invalidated by a lack of other types of evidence.
Again, I have yet to see an alternative explanation for the multiple threads of evidence supporting zoonosis.
“No infected animals at the market” (because samples weren’t taken to look for said infected animals) doesn’t disprove all the other evidence that very clearly points to the market.
Evidence isn’t a carton of milk. It doesn’t expire if you don’t find it. Intermediate hosts of SARS1 and MERS were not found in days as claimed and sometimes they are never found. It took years to find the reservoir for Marburg virus. Nobody debates that it is zoonotic.
Supposedly this was fact-checked by @nytimes—not well enough.
This matters. Watch this clip of Dr. Fauci talking about the sickening threats made against him & his family.
Factually incorrect claims like those in this piece encourage these threats. cnn.com/2024/06/03/pol…
It is grossly irresponsible to say that these 5 unsupported claims mean the pandemic “probably” started with a lab leak. They misrepresent the actual evidence and put people like Dr. Fauci at great risk.
The @nytopinion has shamed itself by printing untruths & outright lies.
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As the accursed ostrich situation continues to get simultaneously more stupid and gravely serious, I decided to write up a very long analysis of many of the key issues. Bottom line: so long as this flock lives, it is a threat to Canada's national security. 🧵
5 months ago I was scrolling & came across some tweets from @sisuvanhell that was my first exposure to the far-right extremist ostrich convoyers. They accused CFIA of sending "murder drones" to covertly cull their flock of ostriches after a H5N1 outbreak open.substack.com/pub/rasmussenr…
In Dec 2024, Universal Ostrich Farms had a confirmed H5N1 outbreak on their remote farm in BC. They did not report to CFIA as required by law. They lost 69 ostriches. CFIA found out anyway & tested 2 dead ostriches. They were positive. They issued a depopulation (cull) order.
This is interesting. The BC ostrich farmers have consistently misrepresented the “scientific research” they were conducting, but it seems they also may have not been entirely truthful about their ostrich meat, oil, & leather business, as well 👇🏻
The ostrich farm claims they are a scientific research facility to study ostrich antibodies. Birds have antibodies in their egg yolks & ostrich eggs are huge, so you can get a lot of antibodies from them. The farmers implied they were studying antibodies to COVID & flu.
But there’s nothing to show that’s true. They’ve never published a paper on the research or shared data/results. There’s a difference between doing research & producing antibodies to sell. According to court documents, they were producing eggs for the latter purpose.
I am always happy to talk to reporters like Nancy MacDonald @globeandmail covering the BC bird flu ostrich story with objectivity & a focus on the evidence.
I hope this clarifies why I think the cull of these birds should proceed whether they are tested or not. Short thread 🧵
The thing people need to realize is that, although the ostriches were infected 10 mo ago, they still pose a health risk & a HUGE economic risk. If CFIA spares them, Canada will violate trade agreements, jeopardizing the entire $2B poultry export market.
CFIA is responsible for ensuring the safety & health of Canadian people & animals by regulating agriculture & food. A big part of the agricultural mandate is to ensure compliance with trade partners' import requirements, to maintain trade. inspection.canada.ca/en/animal-heal…
I'm not uncomfortable with an interview. I don't wish to contribute to anti-government extremist propaganda that imposes the will of a few on Canada's health, food security, economy, & $2B poultry export market. I believe in upholding the law.
1. You can test these ostriches for antibodies. To do it reliably you need to do either a microneutralization or a hemagglutinin inhibition (HAI) assay. These require a high containment lab & trained personnel with HPTA security clearance because they use live virus.
Not many labs in Canada can do these tests. You can't do ELISAs due to cross-reactivity across other flu subtypes. Many overlapping subtypes circulate in birds (H5Nx; HxN1) & humans (H1N1). So you can't just measure antibody binding by ELISA, you must do HAI or microneuts.
I take Ozempic, a GLP-1 agonist, for weight loss. I lost 80 lbs. It has completely transformed my life and health, both physical & mental. But it is not without cost.
Microdosing without evidence is a bad idea. Here are a few reasons why👇🏻
I wrote about this about 6 months ago, when the MAHA Executive Order came out hinting that these drugs are bad. I’ll never stop Ozempic unless forced to. It has improved my life immeasurably.
But I knew the risks & benefits because it had been tested extensively for weight loss
Our methods for evaluating drugs rely on rigorous, well-controlled clinical trials. It allows patients & doctors to make informed decisions. GLP-1 agonists are great for diabetes & weight loss in many people. We know this because of a mountain of clinical trial data.