William Makis MD Profile picture
Aug 31, 2024 1 tweets 3 min read Read on X
NEW ARTICLE: IVERMECTIN should be given to ALL Advanced Breast Cancer patients - outperforms chemo Paclitaxel and kills Cancer Stem Cells!

A 2017 bombshell study by Mexican researchers should have changed how Breast Cancer is treated. Forever.

In the 2017 paper "Ivermectin as an inhibitor of Cancer Stem Cells", researchers from Mexico City take on a theory that Ivermectin could annihilate Breast Cancer Stem Cells.

How long has it been known that Ivermectin can be used to treat cancer? Since 1996!

What are Cancer Stem Cells?

"Although the largest cell burden of a tumor is formed by the so-called bulk tumor cells, a small subpopulation of cells within the tumor has recently been identified, which presents a stem cell phenotype, due to the similarities to these cells have been called “cancer stem-like cells” (CSCs)"

"This cell population generally has the characteristic of unlimited self-renew" and is responsible for metastasis and recurrence

In 2009, MIT and Harvard researchers discovered that an anti-parasitic, Salinomycin, could reduce Breast Cancer Stem Cells by more than 100 fold compared to chemotherapy paclitaxel (Taxol), and inhibit breast tumor growth.

The Mexican researchers in this study searched for the molecule most resembling Salinomycin and after searching 1623 compounds, they found it - it was IVERMECTIN!

“Ivermectin preferentially inhibits the viability of Cancer Stem Cell - enriched populations compared with the total cell population. The opposite pattern was observed with paclitaxel treatment.”

Ivermectin also decreased expression of three "stemness genes" reported to be highly expressed in Cancer Stem Cells.

CONCLUSION: “In conclusion, results from the present study demonstrated that ivermectin preferentially targeted the stem cell population in MDA-MB-231 human breast cancer cells.

Ivermectin has been demonstrated to be safe, following treatment of millions of patients with onchocerciasis and other parasitic diseases, which makes it a strong candidate for further studies investigating its potential use as a repurposed drug for cancer therapy.”

The implications are staggering.

1. Ivermectin outperforms chemotherapy (paclitaxel)

2. Ivermectin destroys Cancer Stem Cells which are responsible for Cancer Treatment failure, metastasis and breast cancer recurrence.

3. Ivermectin destroys Cancer Stem Cells at a rate of over 100 fold compared to chemotherapy

4. Ivermectin also downregulates expression of "stemness genes" which are highly expressed in Cancer Stem Cells.

Bottom line: Every Advanced Breast Cancer patient should get Ivermectin to eliminate Cancer Stem Cells and reduce the risks of treatment failure, metastases and recurrence.

So why don't they? I think we all know the answer.

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