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Conor Browne Profile picture
@brownecfm
Oct 17, 2024 • 1 tweets • 1 min read • Read on X
From the text:

'COVID-19 can accelerate progression of dementia and induce BBB disruption and inflammatory blood clots causally linked with neuroinflammation and neuronal loss'.

BBB - Blood Brain Barrier.

Neurological sequelae of C-19 will be a huge challenge in the future.

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More from @brownecfm

Conor Browne Profile picture
Dec 28, 2025
1. Sometimes, the absurdity of the situation we're all in just hits me. Going forward, ongoing and continuous transmission of SARS-CoV-2 will lead to an ever-increasing percentage of the global population developing chronic illnesses due to sequelae of infection.
2. Simultaneously, the immune dysregulation effect of infection will continue to create opportunities for other pathogens to infect, disable, and kill. One of those pathogens might well start the next pandemic.
3. In many countries, politics and the institutionalisation of anti-vax and pro-infection ideologies are actually encouraging this outcome. This is, to the best of my knowledge, unprecedented in human history: Humanity being overtly on the side of the virus, basically.
Read 4 tweets
Conor Browne Profile picture
Dec 15, 2025
1. As a result of the current high prevalence of influenza and the accompanying media coverage of the spread of the disease, I've been asked about mitigations by a number of friends who take *no precautions against SARS-CoV-2*. A few observations regarding these conversations:
2. Very few people understand just how vastly more effective an FFP2 / KN95 respirator is versus a blue surgical mask. Interestingly, the fact that Boots (a UK pharmacy chain) actually sells own-brand FFP2s is a convincing point for some people: the power of a trusted brand.
3. The false binary nature of influenza vaccination is also obvious in these conversations. Some people seem to have difficulty with the fact that vaccination significantly reduces risk of infection and severe disease, but does not necessarily eliminate it.
Read 6 tweets
Conor Browne Profile picture
Nov 22, 2025
1. The growing prevalence of H3N2 subclade K influenza - the strain driving this year's flu season - combined with the increasing prevalence of H5N1 and now H5N5 (I doubt the WA fatality is the sole human case) is a dangerous recipe for reassortment.
2. Influenza surveillance at the federal level in the US has been drastically reduced as a result of the current administration's very unwise budget cuts; human cases of H5N1 and potentially H5N5 are very likely not being detected.
3. As such, the first warning the US could have should a new, severe influenza strain emerge as a result of a reassortment event could well be an emergency room suddenly full of patients in acute respiratory distress.
Read 4 tweets
Conor Browne Profile picture
Nov 20, 2025
1. I never think that the people at events I attend who aren't mitigating (which in Northern Ireland is essentially everyone) are clueless, careless, or useless. I actively like seeing people experiencing joy, although I am often concerned for them.
2. The broader point here is that I think it is deeply unhelpful to adopt a quasi-Manichean view of the world dividing people solely by whether they mitigate or not; life is infinitely more complex than that. The world is full of very good people who don't mask.
3. Likewise, there are people who mitigate purely out of self-interest and are not particularly good people in other aspects of life. Also, because so few people mask, feeling contempt for those people is very close to misanthropy. Masking is not the sole indicator of morality.
Read 4 tweets
Conor Browne Profile picture
Nov 2, 2025
1. My background is in CBRN defense. I was involved in the field long before the emergence of SARS-CoV-2.

I used to essentially discount comments on social media - especially this platform - as fringe, not representative of the real world. Sadly, this is no longer the case.
2. The current US administration communicates, and arguably governs, through social media. This means that comments on this platform from Americans can no longer be discounted as simply bots; they are representative of the views of a significant proportion of the US population.
3. With that in mind, let me be very, very clear.

The mainstreaming of anti-vax ideology and the disregard and vilification of non-pharmaceutical interventions, including masking, has rendered the US more vulnerable to biological attack than at any time in its history.
Read 4 tweets
Conor Browne Profile picture
Nov 1, 2025
1. Fundamentally, a significant part of what I do is the prediction of both the behaviour of pathogens in the future and our likely collective response to future pathogenic threats. I have an excellent track record in this regard for two main reasons:
2. First, while I recognise the enormous value of quantitative data - and it *is* incredibly valuable - qualitative data is often overlooked by other individuals and organisations in this space.
3. Small outbreaks of unknown diseases are often not picked up in surveillance data; sometimes they appear and disappear in one discrete location, seen as an anomaly by an individual healthcare professional.

*All outbreaks of novel diseases begin as anomalies*.
Read 9 tweets

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