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Conor Browne Profile picture
@brownecfm
Oct 17, 2024 • 1 tweets • 1 min read • Read on X
From the text:

'COVID-19 can accelerate progression of dementia and induce BBB disruption and inflammatory blood clots causally linked with neuroinflammation and neuronal loss'.

BBB - Blood Brain Barrier.

Neurological sequelae of C-19 will be a huge challenge in the future.

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More from @brownecfm

Conor Browne Profile picture
Apr 15
1. The responses to this illustrate a point I've been making for years: namely, that people tend to view the causation behind what is asserted here as binary. It was *either* the societal non-pharmaceutical interventions (notably, the lockdowns) *or*...
2. ... the direct effects of the SARS-CoV-2 virus that significantly altered many societies globally (some much more so than others).

As I first explained on a client call with a major international energy company in 2020, pandemics are social phenomena.
3. That is to say, societies are changed by both the direct effects of the pathogen responsible for the pandemic (in this case, SARS-CoV-2) - mass death, disease, and disability - and by governments' responses to the situation. In other words, *causation is multi-factorial*.
Read 7 tweets
Conor Browne Profile picture
Apr 3
1. As I have stated before on this platform, political decisions are often inextricably linked with biological risk - governmental policies can both mitigate or increase (or even create) biological risks. In that sense, one cannot assess biological risk in isolation of politics.
2. The domestic policies of the current US administration - severe cuts to federal public health programs, reduced disease surveillance, and sowing doubt regarding the effectiveness of vaccines (to name but a few) are clearly risks to the health of the US population.
3. The foreign policies of the US administration - cuts to USAID is a pertinent example - and the current war in the Gulf, which will adversely affect global medication and medical supply chains, and also increase global food insecurity, are clearly threats to global health.
Read 4 tweets
Conor Browne Profile picture
Feb 23
1. Yes it did, and it continues to do so. SARS-CoV-2 is a virus that, amongst many other symptoms, can cause profound fatigue and cognitive dysfunction. Long Covid - much more common than people realise - can extend these symptoms for months, years.
2. Remembering that the virus can infect and re-infect on a very regular basis, a significant percentage of the global population are experiencing these symptoms at any given moment. This is one component of the break in society you are correctly observing.
3. Now layer on top of that the taboo around discussing Covid-19, the politicisation of both the disease and any efforts to mitigate it, and an environment of mass denial is created. This denial is a weight the vast majority of people don't realise they're carrying, but they are.
Read 4 tweets
Conor Browne Profile picture
Dec 28, 2025
1. Sometimes, the absurdity of the situation we're all in just hits me. Going forward, ongoing and continuous transmission of SARS-CoV-2 will lead to an ever-increasing percentage of the global population developing chronic illnesses due to sequelae of infection.
2. Simultaneously, the immune dysregulation effect of infection will continue to create opportunities for other pathogens to infect, disable, and kill. One of those pathogens might well start the next pandemic.
3. In many countries, politics and the institutionalisation of anti-vax and pro-infection ideologies are actually encouraging this outcome. This is, to the best of my knowledge, unprecedented in human history: Humanity being overtly on the side of the virus, basically.
Read 4 tweets
Conor Browne Profile picture
Dec 15, 2025
1. As a result of the current high prevalence of influenza and the accompanying media coverage of the spread of the disease, I've been asked about mitigations by a number of friends who take *no precautions against SARS-CoV-2*. A few observations regarding these conversations:
2. Very few people understand just how vastly more effective an FFP2 / KN95 respirator is versus a blue surgical mask. Interestingly, the fact that Boots (a UK pharmacy chain) actually sells own-brand FFP2s is a convincing point for some people: the power of a trusted brand.
3. The false binary nature of influenza vaccination is also obvious in these conversations. Some people seem to have difficulty with the fact that vaccination significantly reduces risk of infection and severe disease, but does not necessarily eliminate it.
Read 6 tweets
Conor Browne Profile picture
Nov 22, 2025
1. The growing prevalence of H3N2 subclade K influenza - the strain driving this year's flu season - combined with the increasing prevalence of H5N1 and now H5N5 (I doubt the WA fatality is the sole human case) is a dangerous recipe for reassortment.
2. Influenza surveillance at the federal level in the US has been drastically reduced as a result of the current administration's very unwise budget cuts; human cases of H5N1 and potentially H5N5 are very likely not being detected.
3. As such, the first warning the US could have should a new, severe influenza strain emerge as a result of a reassortment event could well be an emergency room suddenly full of patients in acute respiratory distress.
Read 4 tweets

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