Maria Van Kerkhove Profile picture
Nov 2 • 19 tweets • 5 min read • Read on X
As we head into the winter season in the northern hemisphere, I am worried about current #COVID19 vaccination levels.

A short thread 🧵about where we are and what we need to be doing…
Vaccination remains a critical tool for preventing the serious impacts of #COVID19, especially in those at high risk of severe disease - including older adults, individuals with chronic or immunocompromising conditions, pregnant women, and health and care workers. Image
A number of recent studies continue to demonstrate the impact #COVID19 vaccines have had in preventing death and disability from both acute COVID-19 and increasingly from Post COVID-19 Condition (PCC or #LongCOVID) & more research is needed. However...

thelancet.com/journals/lanre…
...current vaccination levels are very low globally. As of the latest data (to 30 June) only 0.81% of older adults are reported as having been vaccinated in 2024 (from 63 countries). In health & care workers, this is lower at 0.35% (from 42 countries).
technet-21.org/en/resources/r…
We see variations in vaccination levels across regions and income groups. Across all groups, uptake in the Americas and European regions and in high- and upper middle- income groups was greater than in other regions and income groups.
As an example, in older adults, uptake rates in the European (2.2%) and Americas (1.8%) regions were considerably higher than in other regions, all between 0.0-0.3% uptake. Also in older adults, HICs had an uptake rate of 2.1%, as compared with 0.37% in LICs.
Based on the latest epidemiological, effectiveness, and safety data, @WHO continues to recommend countries offer a simplified single-dose regimen for #COVID19 vaccines to individuals in high and medium risk groups who have never received a COVID vaccine.
who.int/publications/i…
For those who have been previously vaccinated, @WHO recommends that individuals at high risk of severe #COVID19 get re-vaccinated at an interval of every 6-12 months, depending on the person's risk group, to ensure sufficient protection against developing severe disease and dying
ALL #COVID19 vaccines with @WHO Prequalification (PQ) / Emergency Use Listing (EUL) continue to provide protection against severe disease and death – any of these vaccines can be used either for primary vaccination or for periodic revaccination.
Vaccination should not be delayed in anticipation of access to the latest vaccines. There is a great benefit in receiving ANY approved #COVID19 vaccine as compared to delayed vaccination and certainly compared to having no vaccine.
Importantly, #COVID19 & seasonal #influenza vaccines can be co-administered. As those at greater risk of severe flu are the same as for COVID-19, administering both at the same time (e.g., at the same appointment) may save time & money, while boosting uptake of both vaccines.
As of these next few winter months (in the Northern Hemisphere) typically result in higher respiratory virus burden, a couple of recommendations for individuals and for countries from @WHO:
For individuals – check with your doctor or local health authority to see if you are eligible for vaccination and if #COVID19 vaccines are available in your area. If yes, get vaccinated. It is an important act that can protect you and your loved ones.
For countries – work to accelerate #COVID19 vaccine uptake in risk groups. Use evidence-based strategies to increase confidence in and uptake of COVID-19 vaccines, identifying the root causes of low confidence and tailoring interventions accordingly.

who.int/publications/m…
For countries - integrate #COVID19 vaccination with routine health services & sustain system gains. This is an opportunity to advance the life course approach to vaccination for both new adult vaccines and preparedness for future epidemic/pandemics.

who.int/publications/i…
For countries - finally, continue to collect, analyze, and report #COVID19 vaccine programme data, including vaccine uptake in risk groups.

These data should be used to inform policy and programme decision-making at all levels of the health system, from local to global.
Stay safe, your life is precious.
Another important study (I could share many more, but just some examples as part of this thread).

thelancet.com/journals/lanep…
Another important study (I could share many more, but just some examples as part of this thread).

thelancet.com/journals/lanep…

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More from @mvankerkhove

Jun 24
Despite not being in the news, #COVID19 has not gone away. @WHO continues to work with all countries on surveillance, reporting & risk assessments of circulating variants (JN.1, KP.2, KP.3…) & their impact.

Our latest Epi Update (with variant update) ⬇️
who.int/emergencies/di…
Yes, the impact of COVID is far less than it was in a few years ago, but we can’t become complacent: Recent vaccination coverage in at risk groups is poor, there are ⬆️ trends in hospitalisations in a number of countries, the virus continues to evolve…

technet-21.org/en/resources/r…
… COVID does not circulate with predictable seasonality, our understanding of acute and long term effects (#LongCOVID) is still weak, there is little effort to prevent the spread. Prevention of infection remains impt even with the overall impact of #COVID19 lower than 20-22, etc
Read 4 tweets
May 23
Short 🧵 re #H5N1

An integral component of @WHO’s overall global strategy for #influenza pandemic preparedness activities is the development of candidate vaccine viruses (CVVs) representing influenza viruses of zoonotic and pandemic risk.
Selection and development of #influenza candidate vaccine viruses (CVVs) are the first steps towards timely vaccine production, when needed…
Due to the evolving nature of influenza viruses, the genetic and antigenic characteristics of contemporary zoonotic influenza A viruses and development of CVVs for pandemic preparedness are summarized and published twice a year ().who.int/teams/global-i…
Read 10 tweets
May 5
🧵Lots of interest in #H5N1 in 🇺🇸 so wanted to provide a little background on @WHO’s work in #flu (For latest in US see: @CDCgov @USDA @US_FDA)

And some info on the H5N1 flu vaccine pipeline in humans (note, we don’t need this yet, but I’m getting a lot of questions about this)
@WHO’s work in #flu spans >7 decades with the Global Influenza Surveillance and Response System (GISRS) who.int/initiatives/gl…
GISRS is currently composed of:
152 WHO National Influenza Centers in 130 Member States
7 WHO Collaborating Centers for Influenza and 
12 WHO H5 Reference Laboratories
who.int/images/default…
Read 18 tweets
Mar 29
For the last few years, @WHO and @CERN have been developing a risk assessment tool to estimate indoor airborne transmission of #SARSCoV2 to better advise on risk mitigation measures for #COVID19.🧵

home.cern/news/news/know…
Note: The risk assessment tool itself has been online for more than a year, helping our member states and partners reduce the risks of airborne transmission indoors. 

partnersplatform.who.int/aria
The model behind the tool and updated data from literature reviews were published this week.

We are grateful for the collaboration with @CERN and our ARIA Technical Advisory Group on this incredible work.

iris.who.int/handle/10665/3…
Read 4 tweets
Mar 11
Short 🧵

Many use today as a day to mark significance in the @COVID19 pandemic.

I welcome any way in which we can raise attention to COVID-19, to remember our loved ones lost-and still losing- but also to ensure that we continue to act to tackle the current threat of COVID-19.
It was the day, 4 years ago, the Director-General of @WHO @DrTedros characterized #COVID19 as a pandemic. I remember that day vividly...because it was significant in the lives of everyone on the planet and in mine personally…
But let's accurately mark history here: it's not the day @WHO "declared" a pandemic.

For me, what is heartbreaking is that this day-arguably-marks when the world woke up to the threat of #COVID19, when that awakening should have been at least 6 weeks earlier when DG declared…
Read 8 tweets
Jan 11
Sadly at the end of 2023, we passed the 7 million mark for the number of #COVID19 deaths reported to @WHO. 7,010,586 to be exact. The true death toll is higher, with estimates of at >3 times more deaths globally.

7 million… devastating.

data.who.int/dashboards/cov…
From Oct to Dec, #SARSCoV2 %+ from sentinel sites from @WHO expanded GISRS was 6-10% & from non-sentinel sites was 18% in Dec. Wastewater surveillance systems suggest actual cases are 2-19 times higher than what is reported to WHO.

data.who.int/dashboards/cov…
Worryingly, #COVID19 hospitalisations & ICU admissions are up 42% & 62%, respectively…though data is only available from 29 & 21 countries (out of 234 countries/territories), respectively. We expect these trends to continue following the holidays, but we have limited visibility
Read 7 tweets

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