Arijit Chakravarty Profile picture
Nov 16 27 tweets 10 min read Read on X
(🧵It's the Сονіd, ѕtυріd!): Viewing the US election through the lens of the ongoing ЅАRЅ-Соν-2 раndеmіc.

(My hot take on what happened, and where things are headed. Prelude to the final 🧵in the "How does it end" series)

(1/)
The post-mortem season for the elections is in full swing, and commentators on the left & right have lots of theories about why the Dems lost.

US elections are part of a global trend- incumbent parties in developing countries have lost vote share in every election this year(2/) Image
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A common explanation for this is cost of living. Polls worldwide show dissatisfaction with the cost of living (the gap between the cost of goods & purchasing power), which by some measures is wider than ever before.

(Note that cost of living doesn’t map 1:1 with inflation.) (3/) Image
If inflation causes the price of your daily coffee to rise by 30% over two years, and then goes to 0, that coffee is still a lot more expensive than it used to be! Eventually, of course, wages should catch up- but it's not a guarantee.

Inflation surged worldwide in 2021-22. (4/) Image
More broadly, the idea that the Democratic defeat was due to two things- a surge in inflation and a surge in immigration- has gained a lot of traction in the post-mortem period, and it's easy to see that there might be some truth to this. (5/) Image
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"Since the pandemic", developed countries have been facing significant social & economical upheaval (👀👆).

Making things worse in the US, key measures that (partially) alleviated the cost of living crisis were also eliminated in '21, even as the pandemic continued to rage. (6/) Image
Absenteeism & loss of productivity with Сονіd are well documented.

Labor shortages & reduced growth are the logical consequence of removing people from the workforce - stagflation is the logical outcome if the workforce shrinks far enough. (7/)

(In fact, that's just the tip of the iceberg- pandemics have a broadly negative impact on economic growth & social stability (as described in my recent 🧵👇)).

So, the causal chain: Сονіd- disability- labor shortage - inflation is easy to justify. (8/)

The workforce has, indeed, been impacted by Long Сονіd. This point is not controversial- there are reports from numerous different countries that quantify it, eg:
minneapolisfed.org/research/insti…

brookings.edu/articles/new-d…
cidrap.umn.edu/covid-19/two-s…

(9/)
News media throughout the pandemic have reported on labor shortages: name any high-contact profession you can think of. These shortages have been across multiple sectors in the US, and widely observed in other countries. (10/)

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The media often talks about these labor shortages without bringing up Сονіd- some creatively ascribe shortages to the brief lockdowns in '20 (remember those?). In an ongoing pandemic of a disabling disease, "special pleading" about unique explanations only gets you so far. (11/)
The pandemic is not over, of course- far from it. By many measures, the number of people sick & disabled is not shrinking.

If you take no precautions, you can expect to get Сονіd 1-2x/yr, with a low (15%) but non-declining risk of LC from each infection. The math is ugly. (12/) Image
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(The number of individuals actively seeking disability can also decrease because people drop out of the workforce).

As expected, the US workforce contracted sharply at the beginning of the pandemic, and took several years to recover. (13/) Image
How did the workforce rebound? Was it because people with LC eventually recovered? The data showing long-term recovery for LC is not encouraging, and in fact a case can be made that LC gets progressively worse for many who have it. So that's not it.

(14/)cidrap.umn.edu/covid-19/9-10-…
As it so happens, the immigrant population in the US has grown in leaps and bounds during the (ongoing) pandemic.

There are ~7 m immigrants more in the US now than before the pandemic. Interestingly, it's not just illegal immigration- legal immigration is also up sharply. (15/) Image
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Newer immigrants, bucking a trend, are coming in with lower levels of education than the US born.

It's not hard to see that this wave of immigration is acting to blunt the labor shortages for those in high-contact professions (e.g. retail) and those disabled by LC. (16/) Image
Recent immigrants - legal or illegal- who come to the US to work, and become disabled by LC, have no recourse to our safety net. If they're disabled (legal or not), they go back home. No safety net until the green card, which takes years. This approach creates an underclass (17/)
Meanwhile, the Fed repeatedly put the squeeze on wage growth- the topic was mentioned explicitly in FOMC meetings& press releases by Powell.

So labor supply contraction (due to disability) caused upward wage pressure, which was combated using high interest rates. Great. /s (18/) Image
Meanwhile, immigration policy is weaponized to bring in an underclass of workers with no recourse & no claim on our safety net.

Taken together, the admin took a problem (pandemic -> labor shortage -> inflation) & "fixed" it in the most shortsighted & callous way possible. (19/)
The truth of the matter is- you can't fix a pandemic with PR. People taking no precautions will get infected continuously & some will become disabled. Millions newly disabled each year- an enormous human tragedy- will create a frictional drag that'll tow the economy under. (20/)
No country can expect sustained 3% growth, if 3% of its workforce drops out every year.

There is no path forward - for the US or any other country - without addressing this. Repeated covid infections are not a sustainable situation.

This problem won't go away on its own. (21/)
The incoming administration has clearly expressed a set of specific policy preferences: reduced access to vaccines, cutbacks on immigration, loosened monetary policy.

Each of these policy preferences, if enacted, will pour gasoline on this smoldering fire. (22/)
Leaving a long-running pandemic unaddressed is just incredibly bad Public Health policy. This administration's performance on Сονіd has been an unmitigated disaster, with millions dead & disabled, as PH spent its effort getting the public to courageously "accept infection" (23/)
There are many other things that can go wrong with Сονіd, but this alone will make this course of action unsustainable- you cannot contract your labor force continuously and hope for economic growth.

It's trillions of dollars in lost revenue and unneccessary expenses. (24/)
Сονіd remains a fixable problem.

For a fraction of that cost, efforts aimed at suppressing ЅАRЅ-Соν-2 could make the disease a lot less common & far from inevitable (more on this in the next 🧵).

Biden's failure on Сονіd doomed his legacy.

This virus is not red or blue. (25/)
@sophia_surfs When Harris asked what she would do differently from Biden on the View, she said “not one thing.” And then said “maybe I would’ve had a Republican on my cabinet”

The swing to the right was nationwide, and strongest in low income groups & minorities. (2/) Image
@sophia_surfs Show me where in the county breakdowns & exit polls you see sexism & racism. Accusing minorities & women of sexism & racism is not productive. Refusing to nominate women candidates is the wrong lesson to take away, imo.

Either way, this is off topic, the 🧵 is about Covid. (3/3) Image
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More from @arijitchakrav

Oct 24
(🧵, CAN WE TALK ABOUT IT?):Over the last 5yrs, we as a society have developed a set of norms about 𝐂𝑂𝑉𝐈𝐃. As someone who's been actively publishing on the subject, I notice it very strongly. People will ask "why are you still masking", then wince when they hear my reply(1/) Image
I find it almost amusing, because our friends & famly know I work on the subject, & they're usually the ones that bring it up first. But my reply is obviously not what they want to hear, so I often get the "that was too much" look from my wife & kids in these situations (2/)
This plays out in the public sphere as well. "Expert" opinion that's soothing or reassuring is platformed, even if it's repeatedly wrong. This is a form of propaganda ("Calm-mongering" @Tryangregory ), & distracts us from the reality : (3/) typingmonkeys.substack.com/p/calm-mongeri…Image
Read 28 tweets
Oct 19
(🧵NO ONE COULD HAVE PREDICTED THIS): To answer the question "What does the future hold for 𝑆𝐀𝑅𝑆-𝐂𝑂𝑉-𝟐?" it's worth examining how predictable its evolutionary trajectory has been so far. Evolution is stochastic, but stochastic processes can still yield predictions. (1/)
Paradoxically, while evolution is highly unpredictable at a molecular level, predicting its consequences and anticipating its risks is actually quite easy. We'll dive a lot deeper into this idea in a later TT, as it's a crucial one for understanding our current situation. (2/)
While "expert" prognostications from the early pandemic were wildly off-base, it was possible to reason deductively. We (my collaborators & I, h/t in particular @madistod & @debravanegeren) called out many of the risks within the first year, in the peer-reviewed literature. (3/)
Read 24 tweets
Oct 17
(🧵2/5, HISTORY): What does history teach us about pandemics?

This is a topic that's been covered by others, but much of what's been said is worth taking a closer look at, in context.

Let's look at some historical pandemics/epidemics & see what we can learn. (1/)
It's worth starting by defining what a pandemic is- and isn't. To quote Michael Osterholm (in '09): “(A) pandemic is basically a…novel agent emerging with worldwide transmission.”

It's an epidemiological, not a social, construct. Pandemics don't go away if you ignore them. (2/) Image
In the last 🧵, we looked at what biology tells us about emergent pathogens.

The key take-home: the evolution of their virulence is unpredictable- it often increases.

Host & pathogen are locked in a Red Queen's Race (3/). It's not a stable equilibrium.

Read 27 tweets
Oct 13
(🧵1/5, EMERGENCE): What happens to virulence after a new pathogen emerges? Popular thinking on the subject is that pathogens evolve become less virulent over time when they co-exist with their host species, based on the logic that virulent pathogens don't spread effectively.(1/)
This perception is occasionally echoed by experts as well, for example in this Science article: “𝑆𝐀𝑅𝑆-𝐂𝑂𝑉-𝟐 is going to become a common cold. At least that’s what we want.” (If wishes were horses, then zoonotic spillover would be nothing to worry about, I guess?) (2/) Image
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The idea dates back to the "Law of Declining Virulence", propounded by medical doctor Theobald Smith in the 19thC (far from the last MD to confidently hold forth on the topic of evolution). Unfortunately, it's not supported by experimental data (see screenshots for example). (3/) Image
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Read 26 tweets
Oct 12
(🧵 0/5, Foreword):

It's been ~5yrs since 𝑆𝐀𝑅𝑆-𝐂𝑂𝑉-𝟐, the virus that causes 𝐂𝑂𝑉𝐈𝐃, made its fateful jump into humans. Now seems as good a time as any to ask "is it over yet?" (For the 10th time, but who's counting?)

Let's talk about how this ends, shall we? (1/)
Every few months over the past 5 yrs, we've been reminded that the pandemic is over now, or perhaps it ended a long time ago, no one really knows.

The important thing is that it'll never go away, so we have to learn to live with it.

But not to worry, it's all very mild. (2/) Image
The dead moth buried in that word salad is the belief that newly emergent pathogens must eventually become endemic, that this process is about managing our own feelings about the situation.

A seven-stages-of-grief thing that we must all eventually accept. For our own good. (3/)
Read 26 tweets
Oct 2
Been doing some thinking about how the pandemic will end (@TRyanGregory & @madistod have been great sounding boards).

In particular, focusing on two questions relevant for sc2:

1. What does biology teach us about emergent pathogens?
2. What can past pandemics teach us?

(1/)
TL; DR is we’re all gonna die.

Just kidding. (Actually true if you wait long enough, but that thought is not an original one).

Some interesting titbits, details to follow): (2/)
1. There is a wealth of biology literature on pathogen emergence & what happens to virulence.

It’s a very well studied problem and the stuff you hear “experts” say on the topic is quite different from what the literature says on it. The “experts” are using 1980s textbooks. (3/)
Read 8 tweets

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