🧵 #MedTwitter IMPORTANT
The case of this 🇨🇦 adolescent with #H5N1 #BirdFlu is terrifying. Her only medical history was mild asthma, & symptoms started w/ fever and conjunctivitis. On d5 from symptom onset, she was admitted in respiratory failure, kidney failure, in shock … /1
The case of this 🇨🇦 adolescent with #H5N1 #BirdFlu is terrifying. Her only medical history was mild asthma, & symptoms started w/ fever and conjunctivitis. On d5 from symptom onset, she was admitted in respiratory failure, kidney failure, in shock … /1
Despite 3 antivirals (oseltamivir, amantadine, & baloxavir) to which her virus appeared to be susceptible & plasma exchange (three times !!), she spent 2 wks on ECMO and almost 3 wks on a ventilator and was dialysis-dependent. She survived. Let her be a warning, #MedTwitter /2
In an H5N1 outbreak, if even a small % of people get so sick, hospitals are in trouble. If a #H5N1 virus gains ability to spread btwn humans & enters widespread circulation, humanity is in trouble. No amount of #publichealth effort or cost to prep for #BirdFlu is too great. /3
Evolution of #H5N1 virus in a way that makes it more dangerous to humans has already been detected in individual patients during illness. We must ensure such viruses do not enter the genl population, which could produce a #BirdFlu #HPAI #pandemic. /4
nejm.org/doi/full/10.10…
nejm.org/doi/full/10.10…
#MedTwitter #H5N1
We need:
👉Improved indoor air quality, esp in crowded &/or essential public spaces (schools a top priority)
👉Clear messaging about value of masks & handwashing, as well as avoiding personal/pet contact w/ sick/dead birds
👉Universal paid sick leave
AND
/5
We need:
👉Improved indoor air quality, esp in crowded &/or essential public spaces (schools a top priority)
👉Clear messaging about value of masks & handwashing, as well as avoiding personal/pet contact w/ sick/dead birds
👉Universal paid sick leave
AND
/5
👉Safe, effective, affordable, & readily accessible vaccines & drugs to prevent/treat #H5N1 #BirdFlu.
The time to do all of this is now, not when we are in a crisis that would have major implications for human health/survival as well as the economy on a global scale.
/6
The time to do all of this is now, not when we are in a crisis that would have major implications for human health/survival as well as the economy on a global scale.
/6
#MedTwitter
You can read more about the case of the Canadian adolescent here, & everyone who sees patients in any specialty should read it because we learned from #COVID19 that in a #pandemic, we WILL all be called upon to help in some way:
.
/7nejm.org/doi/full/10.10…
You can read more about the case of the Canadian adolescent here, & everyone who sees patients in any specialty should read it because we learned from #COVID19 that in a #pandemic, we WILL all be called upon to help in some way:
.
/7nejm.org/doi/full/10.10…
#MedTwitter
The risk of #H5N1 #BirdFlu to genl public (w/o contact with ill/dead birds etc) is low at this time per @WHO. What we must let the public know is that that could turn on a dime. We should have prepared so well that if it does, we can run that play in our sleep. /End
The risk of #H5N1 #BirdFlu to genl public (w/o contact with ill/dead birds etc) is low at this time per @WHO. What we must let the public know is that that could turn on a dime. We should have prepared so well that if it does, we can run that play in our sleep. /End
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