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T. Ryan Gregory Profile picture
@TRyanGregory
Jan 18 • 4 tweets • 1 min read • Read on X
As you read more and more reports of uncommon pathogens infecting a lot of people, or common pathogens surging far more than usual and/or having unusually severe effects, please remember that this is what immunity theft predicts and what we've warned about for years.

1/
By contrast, "immunity debt" or "post-pandemic normalizing of levels" as an explanation makes less and less sense as more time goes by. In 2025, it is absurd to still be talking of new surges of illness being due to the lack of immunity from mitigations that ended years ago.

2/
Case in point, we wrote this more than 2 years ago.



3/calgaryherald.com/opinion/column…
And here we still are in 2025.



4/surreynowleader.com/opinion/analys…

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More from @TRyanGregory

T. Ryan Gregory Profile picture
Jan 15
Lots of things in biology correlate with "latitude" (biodiversity, population size, body size, etc.), but "latitude" itself isn't a thing in and of itself. What actually matters is photoperiod, temperature, precipitation, etc. That's how we should think of "seasonal" as well.

1/
Viral transmission may be strongly and predictably "seasonal", mostly occurring during certain times of the year (flu, RSV), but it's not either-or. Other viruses may be common year-round but also increase at certain times of the year.

2/
However, it's not "season" per se, it's things that vary throughout the year. Mostly this involves human behaviour (travel, congregating, being indoors more, school in or not, etc.). There may also be effects of environmental variables like UV, wind, temperature, humidity.

3/
Read 5 tweets
T. Ryan Gregory Profile picture
Jan 12
So, I'm not sure the American right has thought through the implications of annexing Canada yet.

A few things to consider...

1/
First of all, Canada has a slightly larger population than California, so presumably we'd get at least 54 electoral college votes in presidential elections. Polls here showed that about 61% of Canadians would have voted for Harris and 21% for Trump.



/2globalnews.ca/news/10830218/…
Now, it would be pretty weird and surely a big ego bruiser to have one state being physically larger than the entire rest of the country combined, especially if it's blue on the electoral map. So presumably Canada would represent several states, not one.

3/
Read 10 tweets
T. Ryan Gregory Profile picture
Dec 5, 2024
(Sarcasm alert) The way viral evolution works is that if you have a naïve idea of how it works and that helps with calm-mongering, that's how it works. Need some examples? 🧵
For example, if it helps with calm-mongering to think that viruses have to evolve to become mild or else they will drive their hosts and themselves extinct, that must be what happens. Don't let actual evolutionary biologists convince you otherwise! (Sarcasm)
Oh, oh -- how about this? If a virus can infiltrate the host's genome permanently and then not cause any harm, that would give it a huge advantage in long-term survival. Therefore, all viruses must evolve to become endogenous in the genome! This is fun! (Sarcasm)
Read 4 tweets
T. Ryan Gregory Profile picture
Nov 8, 2024
One side is consistently painted as violent and the other as being unsafe. Is that accurate? Well, all of these happened on video in Ontario, Canada. 🧵
Attacking with a nail gun while shouting "All Palestinians will die".

Threatening with a baseball bat.

Read 8 tweets
T. Ryan Gregory Profile picture
Nov 4, 2024
How sure are you that only certain people are susceptible to severe acute COVID, and that you're not one of them?

What is your level of certainty that only specific people are vulnerable to long COVID, and that you're not one of them?

1/
Are you certain that repeated SARS-CoV-2 infections won't have cumulative effects?

How confident are you that you don't, or won't ever, harbour a persistent SARS-CoV-2 infection?

Are you totally convinced that SARS-CoV-2 will necessarily become mild and seasonal?

2/
Do you truly believe beyond doubt that "immunity debt" explains the surge in other infectious diseases, years after most major mitigations were dropped and even among kids who weren't born yet during lockdowns?

3/
Read 4 tweets
T. Ryan Gregory Profile picture
Nov 4, 2024
Beyond "immunity debt".

In what ways could SARS-CoV-2 be involved in surges of other infectious diseases like RSV, tuberculosis, fungal infections, Mycoplasma, etc.?

Here is a list of additional hypotheses, all increasingly supported in the scientific literature.

🧵
H1. Temporary immune effects of recent SARS-CoV-2 infection increase susceptibility to other infections.
H2. SARS-CoV-2 infection causes reactivation of latent infections.
Read 17 tweets

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