Page 15/15. Finally all here. Next up we'll fix any broken links or errors people find and think about ways to make this even easier to access and use.
But we managed to save this from oblivion. Hope it helps.
Out today in @ForeignPolicy: I wrote about what will happen if there is an H5N1 pandemic with Robert F Kennedy, Jr. in charge of safeguarding the health of Americans.
If RFK Jr is leading HHS & H5N1 begins spreading human to human, the deaths will be counted in millions.🧵👇
RFK Jr already has a sizable body count (in every sense of the term, but here I'm talking about counting corpses and not sexual partners).
If he has control over HHS in a flu pandemic, deaths attributable to him will increase by orders of magnitude.
Independent of RFK, this is why we're dealing with H5N1. We've known about it since 1997, but in 2020 a new strain emerged that has spread among birds globally since 2021. For more than a year, it has been spreading unchecked in US dairy cows. As a virologist, I am very worried.
@annamerlan asked me to go over the science around some of the claims about raw milk that Mark McAfee, Raw Farm owner and unpasteurized milk evangelist, has made and this shit is wild.
Buckle up for H5N1 denialism, anti-vax, magical antiviral compounds,
McAfee calls H5N1 "a huge scam...by pharma to create fear & produce a new vaccine."
He doesn't think H5N1 is dangerous & says nobody has gotten sick from drinking raw milk or has anything to fear if they've got a "strong microbiome."
Except for all those dead cats, I guess.
What biosafety practices are being employed in his "on-farm pathogen lab"? They say virologists are reckless but this dude is doing DIY pathogen diagnostics for assessing food safety—risk to staff and the consumer with substandard biosafety practices in this setting.
This is bad news. It suggests reassortment of circulating H5N1 viruses with viruses containing N9 NA.
Although this indicates reassortment with avian viruses, it's still bad. Reassortment makes pandemics. The last 3/4 flu pandemics (and maybe 1918 too) were reassortant viruses.
Reassortment is what happens when 2 flu viruses infect the same host. Because influenza A viruses have segmented genomes divided into 8 pieces of RNA, these can be mixed up in new progeny viruses during replication in a co-infected host.
This leads to unpredictable new viruses.
Although the same clade as the H5N1 viruses currently spreading, this H5N9 virus is a different genotype (clade is determined by HA, genotype is the whole virus).
We need to do more surveillance to limit opportunities for different viruses to reassort.
Susceptibility: can the virus get in to cause an infection?
We already know ACE2 from different species have vastly different binding affinities for spike RBD. Sometimes this matters for function as an entry receptor, sometimes not. But to infect a host, a virus has to get in.
New year, new fave conspiracy theory: the global shadow government is spraying infectious fog across the entire northern hemisphere with those possibly alien drones everyone was seeing a couple weeks back. The mystery virus has symptoms exactly like seasonal respiratory viruses.
It doesn’t look like fog because it’s full of floating droplets of something that might be normal fog ingredients (aka water) or it might be carcinogens and/or viruses
I get some pretty wild emails and one of my favorite correspondents hypothesizes that VOGs (volcanic gas emissions) are causing COVID and SARS-CoV-2 was an elaborate false flag operation to hide the real threat.
Has a NIH Director ever appeared in cult-funded propaganda claiming that ivermectin, a drug that doesn't work to treat COVID, was the victim of a conspiracy to obtain FDA authorization for vaccines that do actually work?
There's a first time for everything, I guess.
Because in this Covid Collateral "documentary," Jay Bhattacharya implies that ivermectin was suppressed because it would prevent vaccines from getting regulatory approval.
And in case it's not clear, suggesting that federal drug regulators were conspiring against ivermectin, a drug that again does not work, to promote vaccines that do is an inherently anti-vaccine position. It's also an unscientific conspiracy theory that has no basis in evidence.