Prognostic Chats Profile picture
Feb 28 18 tweets 3 min read Read on X
This "State of the Art Review" on the role of masks & respirators in preventing respiratory infection coming out in the BMJ is worth a deep dive. So I've done that for you.
Some important messages in the 🧵 feel free to share them. Image
1. Keep it on & it works 😷:
“continuous & targeted use of respirators found that respirators were considerably more effective than masks if worn continuously…Intermittent use of respirators or medical masks only when performing high risk procedures was not protective"
2. Respirators are more effective than medical masks:
“early data on Covid (2020); in a subanalysis, respirators were 96% effective compared with masks, which were 67% effective… The overall protection factor of N95 respirators was 8-12 times greater than that of surgical masks”
3. Respirators (FFP2/3, N95) are better than surgical masks, which are better than cloth masks, which are better than no masks:
“The most recent community RCT in Norway showed surgical masks were 29% protective against self-reported respiratory symptoms compared with no mask”
“Aerosol studies have reported that the blocking of exhaled aerosols improves with the number of layers of a mask, and is better with a surgical mask than a cloth mask”
4. Covid can be spread by asymptomatic people & by people before they develop symptoms, so you can’t rely on symptoms to know if someone can infect you: “Asymptomatic transmission of flu has long been recognized, but Covid has a much higher degree of asymptomatic transmission"
4. Covid can be spread by asymptomatic people & by people before they develop symptoms, so you can’t rely on symptoms to know if someone can infect you:
“ It is estimated that 30-50% of SARS-CoV-2 transmission is asymptomatic”
5. This means if you are out in public or sharing spaces, you have no idea how many around you are spreading covid into the air, masks are needed: “people who are sick or healthy cannot self-identify risk of exposure in a crowded public setting unless testing is done"
6. Asymptomatic & presymptomatic Covid spread with no one masking is allowing Covid to have constant waves of infection still: "This is one of the strongest justifications for mass masking during epidemic waves of SARS-CoV-2” (that is now)
7. ANY mask is better than no mask: “The evidence shows that respirators offer better protection than masks, but that any protection is better than none during a pandemic or serious emerging respiratory infection”
8. How your mask fits your face is key, a tight fit offers better protection: “A loosely fitted respirator could provide the same protection as a medical mask, while a tightly sealed medical mask or respirator will significantly improve the protection”
9. Hospitals and masking. I felt this line deep in my soul: “for a health worker, the hazard is the job itself; they must treat patients with deadly infectious diseases, and removal of these patients or substitution of them is clearly not an option”
10. Covid spread in hospitals is a huge ongoing issue: “Nosocomial covid is a major, ongoing problem, with a high mortality rate”
“Covid has substantial transmission in the asymptomatic or presymptomatic period, universal masking can have a major impact on flattening the curve”
11. Masking guidelines in hospital is based on money, not evidence: “The evidence from healthcare supports N95 use, but continuously rather than occasionally in self-identified situations of risk. Targeted N95 use might be a cost saving measure, rather than evidence based policy"
12. Changing won’t be easy: “This will require a major paradigm shift because guidelines to date recommend targeted use of respirators in very select situations...studies suggest using cheaper, less effective masks, might end up being costlier in the long run for hospitals”
13. Conclusion: “there is ample evidence on the effectiveness of masks & respirators in community & healthcare settings to inform consistent policy. Respirators are superior & should be the 1st choice in a serious emerging epidemic or pandemic in healthcare & aged care settings"
13. Conclusion: "Strong leadership is required to overcome politicization & polarization around masks”

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More from @PrognosticChats

Feb 28
The following statement from the JCVI has been copied & pasted into NHS communications this week to "reassure" all staff that we are post covid, that everyone is immune & that its "mild" & death rates & hospitalisations are all low.
I've attached evidence to show this is false.🧵 Image
"Over the last 4 years, population immunity to SARS-CoV-2 has been increasing due to a combination of naturally acquired immunity following recovery from infection and vaccine-derived immunity (this combination is termed ‘hybrid immunity’)"

here's our immune population 2024... Image
"COVID-19 is now a relatively mild disease for most people, though it can still be unpleasant, with rates of hospitalisation and death from COVID-19 having reduced significantly since SARS-CoV-2 first emerged"

deeply "unpleasant" for those dying ("mild"??) & getting long covid Image
Read 5 tweets
Feb 22
It’s only a matter of time until Covid is shown to cause cancer & more rapid cancer growth. Renal, pancreatic, ovarian, melanoma, lung, I’ve seen growth rates & first presentations the like of which I’ve never encountered before. Covid is proven to dampen a tumour suppressor gene
But, much like the news that Covid causes increased heart attack, stroke & sudden death risk for at least 3 years after an infection, most people will ignore any news about cancer risk & just keep on pretending like Covid doesn’t exist. Although that’s easier, Covid won’t care.
Here’s a little video showing what p53 tumour suppressor protein does for us all…
nature.com/articles/d4158…
Read 7 tweets
Feb 20
Covid can give you chronic illness known commonly as Long Covid or Post Acute Covid Syndrome(PACS) with any organ being damaged

It has no cure & no available or accepted treatment

Your chance of recovery is less than 2% over the first 3 years

Recovery isn’t even fully ‘ok’
🧵 Image
You can get Long Covid/ Post-Covid Syndrome after your 1st, 2nd, 3rd, 4th, 5th infections. Every time you are infected you run the risk of post Covid Syndrome with a variety of potential life changing complications, none of which have a cure
Long Covid risk in adults is often quoted around the 10% mark with any Covid infection, but depending on where you look it can be much higher (30%) or much lower (4%).
Knowing what it can do to you, any % should be enough to take infection seriously. Image
Read 9 tweets
Feb 2
The most terrible loneliness is not the kind that comes from being alone, but the kind that comes from being misunderstood.
It is the loneliness of standing in a crowded room surrounded by people who do not see you, do not hear you, who do not know the true essence of who you are Image
And in that loneliness, you feel as though you are fading, disappearing into the background, until you are nothing more than a ghost, a shadow of your former self.
George Orwell, 1984

Lone maskers, especially in healthcare settings, may relate to that sense of isolation. Yet…
You know you are following the scientific evidence, responding to what is actually happening all around you, trying to maintain your health if you’ve already been scarred or are wishing not to be. Feeling isolated as no one else seems to be doing the same, or even mentioning it.
Read 7 tweets
Dec 10, 2024
Dear anyone with cancer,
If you get Covid you might die.
You might die immediately with the acute infection.
You might die after the acute event with blood clots (increased risk already with cancer + Covid).
You might die because your chemo/immunotherapy has been delayed so much.
You might die after a prolonged admission with infection & other resultant organ damage.
You might die because your surgery gets postponed because of your Covid.
You might die because you never get back on treatment as you are so unwell post acute Covid.

Wear a mask. Keep safe.
Ask your family & friends to help you not die during your cancer treatments by masking to keep you safe.

Protect the other cancer patients around you at clinic by wearing a mask, then they may not die due to a Covid infection either.

Unbroken treatment gives you the best chance
Read 5 tweets
Dec 10, 2024
I was on a ward full of immunocompromised patients today with active Covid cases & I was the only one wearing a mask (that includes patients & visitors).

I have reached a point of quiet resignation. I’ve tried & tried to help the patients & the staff but they don’t want help
🧵
Numbers of Covid patients are climbing. Again. Entirely predictable as Christmas parties pick up pace & people gather more in packed crowds, with few vaccinated & absolutely no masks or adequate air filtration. But also predictable on the wards, with no masks or staff testing…
all of the staff, spare a solitary few who still recognise we are working & living in a pandemic, being out at all the aforementioned parties. Coming into work, not testing, not bothering to mask on a Covid ward. Living the delusion that it somehow stops at the patients door🙃
Read 6 tweets

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