Gaurab Chakrabarti Profile picture
Apr 3 20 tweets 7 min read Read on X
In 1919, a silent killer swept through New York.

Scientists warned: one teaspoon causes blindness - one glass brings death.

But people continued to drink it.

Here's how the U.S. government created the most lethal poison epidemic in history (killing 10.000): Image
In January 1919, the 18th Amendment was ratified.

It prohibited alcohol production and sales across America.

But demand remained strong.

This created a massive black market for bootleg liquor...
With legal sources gone, bootleggers turned to industrial alcohols, like wood alcohol.

But wood alcohol (methanol) turns into formaldehyde and formic acid in the body.

These lead to blindness, organ failure and death.

Why were so many drinking this poison?
Industrial alcohol was still legal - used for manufacturing, cleaning, and other purposes.

Bootleggers bought this alcohol, redistilled it (to remove toxic additives) and then sold it.

In 1926 the U.S. Treasury made a fateful decision that would cost thousands of lives:
They deliberately increased the toxicity of industrial alcohols to discourage their consumption.

By adding toxic chemicals like benzene, kerosene and even formaldehyde.

Their goal wasn't just to sicken – but to kill...
A Treasury official coldly stated:

"The person who drinks this industrial alcohol...is a deliberate suicide."

But this did not stop bootleggers - in 1926, they diverted about 60 million gallons of alcohol.

The results were catastrophic: Image
In 1926 alone, poisoned alcohol sickened 1,200 New Yorkers and killed 400.

The following year, NYC deaths rose to 700.

Christmas 1926 was devastating, with 23 deaths in just two days.

Here's where the story turns even darker...
When confronted with the death toll, the government did not retract - it doubled down.

"Government isn't obligated to furnish drinkable alcohol when the Constitution prohibits it."

They saw these deaths as necessary deterrents... Image
Meanwhile, the chemical industry boomed:

• Industrial alcohol production jumped from 28M gallons in 1920 to 90M by 1925
• Companies profited selling to both industry and denaturing programs

The human stories are heartbreaking: Image
Jazz legend Bix Beiderbecke drank poisoned alcohol in 1928 and never recovered.

He survived initially, but his weakened body succumbed to pneumonia two years later.

Working class communities suffered most...
They were consuming cheaper bootleg liquor.

By 1933 Prohibition ended.

The government-endorsed poisoning had claimed over 10,000 American lives.

This tragedy led to stronger regulations:
The Federal Alcohol Administration Act of 1935 established strict standards for alcohol production.

The Food, Drug, and Cosmetic Act of 1938 gave FDA broader powers to ensure consumer safety.

While prohibition's poisonings represent a stunning failure of government policy...
They offer a powerful lesson.

When we ignore scientific expertise in favor of misguided policies - the consequences can be devastating.

This resonates deeply with me, as I work to transform one of the most important industries that exist today:
The $6T chemicals industry is the invisible backbone of modern civilization.

It's in every product you touch, every building you enter, and every vehicle you ride.

And we now have the technology to reinvent this critical sector...
At Solugen, we're revolutionizing how essential chemicals are made.

Our enzymatic reactions achieve 96% yields (vs. 60% industry average) while eliminating toxic byproducts.

It's the difference between 1919's wood alcohol and today's precision manufacturing...
But chemical manufacturing processes is just one challenge - next there's outdated logistics.

Huge factories far from customers.

We're solving this problem in the same way mini-mills revolutionized steel manufacturing:
Solugen's Bioforges - a network of smaller, cleaner chemical facilities that allows us to:

• slash costs
• increase efficiency, and
• speed up product delivery

This is how we're bringing critical manufacturing back to American soil...
Follow me @GaurabC for insights on:

• Building the Tesla of chemicals
• Industrial innovation opportunities
• Bringing manufacturing back to the U.S.

Let's strengthen America's backbone: the chemicals industry.
Learn how @solugen is reinventing the $6T chemicals industry.

I sat down with @BaillieGifford to discuss:

• Building carbon-negative cities
• The path to cleaner, safer materials
• The future of distributed manufacturing

Full episode:
Video credits (YouTube):

• Prohibition: America on the Rocks | Historical Documentary | Lucasfilm
• What happened when the United States banned alcohol - Rod Phillips
• U.S. Prohibition (1920-33)
• A Man Drank 2 Liters Moonshine In 2 Hours. This Is What Happened To His Eyes.

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More from @GaurabC

Mar 28
In 1927 Henry Ford built a secret city in the Amazon rain forest.

But only three years later, his employees fled Fordlandia for their lives.

Here's why the jungle swallowed Ford's $400M dream (it wasn't snakes or spiders): Image
Ford's plan was brilliant.

Acquire 2.5 million acres of Brazilian rainforest and build a factory town in the middle of nowhere.

Then grow rubber for his car tires and break free from the British and Dutch rubber cartels.

Ford's managers worked tirelessly for 6 full years:
They cleared 9,000 acres of dense jungle between 1928-1934.

Then, they built a perfect American town featuring:
• Movie theaters
• A modern hospital
• Power plant and water systems

It was Michigan transplanted to the jungle - but there was one major problem...
Read 19 tweets
Mar 1
A backwater boy created one of the world's largest chemical companies—but no one talks about him.

With a $43 BILLION valuation, titans like Bayer and BASF envy his genius.

Here's the forgotten story of how sleeping in a barn led to a $43B chemical empire: Image
Herbert Henry Dow wasn't born into wealth.

His father, a brilliant inventor, struggled financially despite his talents.

When the family moved to Cleveland, Herbert faced true hardship—sleeping in a barn while at Case School.

This forged something extraordinary in him...
Relentless persistence.

At 12, Herbert built an egg incubator after seeing magazine illustrations.

It took failed 40 attempts before success.

When someone copied his design, he simply moved to the next challenge.

During his senior year his destiny found him:
Read 25 tweets
Feb 22
In 1872, one man created an empire 4x the size of Apple.

But Rockefeller never drilled a single well.

He controlled something far more valuable.

The $400 Billion strategy that made a small-town bookkeeper the richest man in the world: Image
Born in 1839 to a traveling salesman, John D. Rockefeller learned early about the power of hustle.

By age 16, he was working as a bookkeeper at a produce broker in Cleveland, earning just $0.50 per day.

But young John had a gift - he could see opportunities others missed.

And in 1859, he spotted something...
Just 100 miles east of Cleveland, the first American oil well had been discovered.

Within a year, 4,500 barrels of oil were being produced.

Everyone rushed to drill for black gold.

But Rockefeller saw an opportunity nobody else did...
Read 19 tweets
Feb 14
Germany unleashed their deadliest weapon in December 1915.

3,000 cylinders of a gas 6x more lethal than chlorine (said to smell like "musty hay").

One breath was enough to turn your lungs into acid.

The story of WW1's silent killer: (and how it shaped the world we live in) Image
In 1812, Cornish chemist John Davy exposed carbon monoxide and chlorine gas to sunlight.

UV radiation from the sunlight kicked off a reaction, forming a new gaseous compound.

He named it "phosgene" - Greek for "born from light."

But this innocent discovery would change warfare forever...
Fast forward to December 1915.

The Germans set up 3,000 cylinders of compressed phosgene gas on the front line.

A light breeze carried a deadly white cloud toward enemy trenches.

What happened next would haunt survivors for decades:
Read 18 tweets

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